EXPERIMENT_TITLE: PTC  HiC
STUDY_DESCRIPTOR_STUDY_ABSTRACT: Spatial chromatin structure is intricately linked with somatic aberrations, and somatic mutations of various cancer-related genes, termed co-mutations (CoMuts), occur in certain patterns during cancer initiation and progression. The functional mechanisms underlying these genetic events remain largely unclear in thyroid cancer (TC). With discrepant differentiation, papillary thyroid cancer (PTC) and anaplastic thyroid cancer (ATC) differ greatly in characteristics and prognosis. We aimed to reveal the spatial gene alterations and regulations between the two TC subtypes.
SAMPLE_TITLE: Human human thyroid tumor cell line  for PTC (BCPAP )
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "isolate", "VALUE": "cell line"}, {"TAG": "age", "VALUE": "76"}, {"TAG": "biomaterial_provider", "VALUE": "Zhong Qiao Xin Zhou Biotechnology Co., Ltd. (Shanghai, China; http://fmgbio.bioon.com.cn)"}, {"TAG": "sex", "VALUE": "female"}, {"TAG": "tissue", "VALUE": "thyroid"}, {"TAG": "cell_line", "VALUE": "BCPAP"}, {"TAG": "cell_type", "VALUE": "human thyroid cell"}, {"TAG": "disease", "VALUE": "thyroid tumor"}, {"TAG": "BioSampleModel", "VALUE": "Human"}]
RUN_SET_RUN_SRAFiles_SRAFile: [{"Alternatives": [null, null], "@attributes": {"cluster": "public", "filename": "PTC-BCPAP_R2_b3.fq.gz", "url": "https://sra-pub-src-2.s3.amazonaws.com/SRR24153637/PTC-BCPAP_R2_b3.fq.gz.1", "size": "37176950878", "date": "2023-04-13 11:06:27", "md5": "ad9c90b68d84ea056c9892a55dd444af", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": [null, null], "@attributes": {"cluster": "public", "filename": "PTC-BCPAP_R2_b2.fq.gz", "url": "https://sra-pub-src-2.s3.amazonaws.com/SRR24153637/PTC-BCPAP_R2_b2.fq.gz.1", "size": "31662921906", "date": "2023-04-13 11:00:19", "md5": "b8c35b3489f382a8a780588d23a52050", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": [null, null], "@attributes": {"cluster": "public", "filename": "PTC-BCPAP_R2_b1.fq.gz", "url": "https://sra-pub-src-2.s3.amazonaws.com/SRR24153637/PTC-BCPAP_R2_b1.fq.gz.1", "size": "1429379207", "date": "2023-04-13 10:44:24", "md5": "6af141940996501cf4e9a765bb31706c", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": [null, null], "@attributes": {"cluster": "public", "filename": "PTC-BCPAP_R1_b3.fq.gz", "url": "https://sra-pub-src-2.s3.amazonaws.com/SRR24153637/PTC-BCPAP_R1_b3.fq.gz.1", "size": "34733239486", "date": "2023-04-13 11:12:06", "md5": "a44f6c2644487298428311eb31c798e5", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": [null, null], "@attributes": {"cluster": "public", "filename": "PTC-BCPAP_R1_b2.fq.gz", "url": "https://sra-pub-src-2.s3.amazonaws.com/SRR24153637/PTC-BCPAP_R1_b2.fq.gz.1", "size": "29575004927", "date": "2023-04-13 10:54:43", "md5": "b1476d3748e56894ddb38e50e89190d5", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": [null, null], "@attributes": {"cluster": "public", "filename": "PTC-BCPAP_R1_b1.fq.gz", "url": "https://sra-pub-src-2.s3.amazonaws.com/SRR24153637/PTC-BCPAP_R1_b1.fq.gz.1", "size": "1356311449", "date": "2023-04-13 10:44:05", "md5": "163cd7f53bc8b9115a70507b4cfae823", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}]