EXPERIMENT_TITLE: High-throughput chromosome conformation capture (simplified Hi-C) of K562 cell line
STUDY_DESCRIPTOR_STUDY_ABSTRACT: We developed HiCNAtra tool to identify high-resolution CNVs (copy number variations) from 3C-seq/Hi-C data of cancer cell lines with abnormal karyotype and to correct the chromatin contact matrices from all systematic biases including CNV-induced bias. In this study, we have generated genome-wide chromatin interaction maps of K562 (chronic myelogenous leukemia) and H69AR (small cell lung carcinoma) cell lines using high-throughput chromosome conformation capture- sequencing (3C-seq) technique.
SAMPLE_TITLE: High-throughput chromosome conformation capture-sequencing (3C-seq) of K562 cell line
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "isolate", "VALUE": "Not Applicable"}, {"TAG": "age", "VALUE": "53 years"}, {"TAG": "biomaterial_provider", "VALUE": "Not Applicable"}, {"TAG": "sex", "VALUE": "female"}, {"TAG": "tissue", "VALUE": "Bone marrow"}, {"TAG": "cell_line", "VALUE": "K562"}, {"TAG": "BioSampleModel", "VALUE": "Human"}]
Pool_Member_@attributes_sample_title: High-throughput chromosome conformation capture-sequencing (3C-seq) of K562 cell line
RUN_SET_RUN_Pool_Member_@attributes_sample_title: High-throughput chromosome conformation capture-sequencing (3C-seq) of K562 cell line
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