EXPERIMENT_TITLE: GSM4198766: BLaER subclone, 24h_CTCF_AID_DMSO_HiC_rep1; Homo sapiens; Hi-C
EXPERIMENT_DESIGN_LIBRARY_DESCRIPTOR_LIBRARY_CONSTRUCTION_PROTOC: Cells were collected by centrifugation. Crosslinked nuclei were digested with MboI followed by fill-in with bio-dATP, in-situ ligation and DNA extraction. DNA was sonicated and libraries were constructed using the the NEBNext DNA Library Prep Kit (New England Biolabs).
STUDY_DESCRIPTOR_STUDY_ABSTRACT: Studies of genome topology, chromatin state and gene expression dynamic during human B cell to macrophage transdifferentiation with and without CTCF Overall design: Genome topology profiling during  human B cell to macrophage transdifferentiation with and without CTCF using insitu HiC
SAMPLE_TITLE: BLaER subclone, 24h_CTCF_AID_DMSO_HiC_rep1
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "source_name", "VALUE": "Leukemia cell line"}, {"TAG": "subclone", "VALUE": "BLaER subclone CTCF-AID (Auxin Inducible Degron)"}, {"TAG": "treatment", "VALUE": "CEBPA+DMSO"}, {"TAG": "time", "VALUE": "24h"}]
Pool_Member_@attributes_sample_title: BLaER subclone, 24h_CTCF_AID_DMSO_HiC_rep1
RUN_SET_RUN_Pool_Member_@attributes_sample_title: BLaER subclone, 24h_CTCF_AID_DMSO_HiC_rep1
RUN_SET_RUN_SRAFiles_SRAFile: [{"Alternatives": null, "@attributes": {"cluster": "public", "filename": "1bce36e87_d1119898d_read1.fastq.gz", "size": "16241949296", "date": "2019-12-01 09:58:23", "md5": "5a2fcea5121128f455e7cb1b2e5413b9", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "1bce36e87_d1119898d_read2.fastq.gz", "size": "16708717932", "date": "2019-12-01 09:38:57", "md5": "183ec221df489b84f5668636ac3dc56a", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "SRR10566628", "url": "https://sra-pub-run-odp.s3.amazonaws.com/sra/SRR10566628/SRR10566628", "size": "21315457686", "date": "2019-12-01 10:24:03", "md5": "77acd3102cfbb5ac43a2e2e3f878b065", "version": "1", "semantic_name": "SRA Normalized", "supertype": "Primary ETL", "sratoolkit": "1"}}, {"Alternatives": [null, null, null], "@attributes": {"cluster": "public", "filename": "SRR10566628.sralite", "url": "https://sra-downloadb.be-md.ncbi.nlm.nih.gov/sos5/sra-pub-zq-16/SRR010/566/SRR10566628.sralite.1", "size": "10467004057", "date": "2020-06-22 19:31:40", "md5": "44f03e3d2da0fe0281b7e83042a01996", "version": "1", "semantic_name": "SRA Lite", "supertype": "Primary ETL", "sratoolkit": "1"}}]