EXPERIMENT_TITLE: HCT_TOP1_IAA_HiC
STUDY_DESCRIPTOR_STUDY_ABSTRACT: We study DNA topology in the context of chromatin organization and gene expression in human cells, utilizing our strength of developing novel genomic technologies and single-cell assays. We seek to understand how the topological tension of the double helix interact with other chromatin features, contribute to the chromatin environment for gene regulation, as well as the involvement, regulation, and function of DNA supercoiling dynamics and topoisomerase activities upon various biological processes.
SAMPLE_TITLE: HCT116_Top1_IAA_HiC
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "strain", "VALUE": "not applicable"}, {"TAG": "age", "VALUE": "not applicable"}, {"TAG": "collection_date", "VALUE": "2024-02-23"}, {"TAG": "geo_loc_name", "VALUE": "not applicable"}, {"TAG": "sex", "VALUE": "male"}, {"TAG": "tissue", "VALUE": "Colon"}, {"TAG": "cell_line", "VALUE": "HCT116-Top1-mAID"}, {"TAG": "treatment", "VALUE": "living cell treated with IAA for 2h, then follow with Hi-C"}, {"TAG": "biomaterial_provider", "VALUE": "missing"}, {"TAG": "isolate", "VALUE": "missing"}, {"TAG": "BioSampleModel", "VALUE": "Human"}]
Pool_Member_@attributes_sample_title: HCT116_Top1_IAA_HiC
RUN_SET_RUN_Pool_Member_@attributes_sample_title: HCT116_Top1_IAA_HiC
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