EXPERIMENT_TITLE: GSM4198769: BLaER subclone, 168h_CTCF_AID_AUX_HiC_rep1; Homo sapiens; Hi-C
EXPERIMENT_DESIGN_LIBRARY_DESCRIPTOR_LIBRARY_CONSTRUCTION_PROTOC: Cells were collected by centrifugation. Crosslinked nuclei were digested with MboI followed by fill-in with bio-dATP, in-situ ligation and DNA extraction. DNA was sonicated and libraries were constructed using the the NEBNext DNA Library Prep Kit (New England Biolabs).
STUDY_DESCRIPTOR_STUDY_ABSTRACT: Studies of genome topology, chromatin state and gene expression dynamic during human B cell to macrophage transdifferentiation with and without CTCF Overall design: Genome topology profiling during  human B cell to macrophage transdifferentiation with and without CTCF using insitu HiC
SAMPLE_TITLE: BLaER subclone, 168h_CTCF_AID_AUX_HiC_rep1
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "source_name", "VALUE": "Leukemia cell line"}, {"TAG": "subclone", "VALUE": "BLaER subclone CTCF-AID (Auxin Inducible Degron)"}, {"TAG": "treatment", "VALUE": "CEBPA+auxin"}, {"TAG": "time", "VALUE": "24h"}]
Pool_Member_@attributes_sample_title: BLaER subclone, 168h_CTCF_AID_AUX_HiC_rep1
RUN_SET_RUN_Pool_Member_@attributes_sample_title: BLaER subclone, 168h_CTCF_AID_AUX_HiC_rep1
RUN_SET_RUN_SRAFiles_SRAFile: [{"Alternatives": null, "@attributes": {"cluster": "public", "filename": "462beb444_d1119898d_read1.fastq.gz", "size": "15279292817", "date": "2019-12-01 09:25:55", "md5": "37f725b55ecb642e7b082766b47c43fb", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "462beb444_d1119898d_read2.fastq.gz", "size": "15586280394", "date": "2019-12-01 09:27:31", "md5": "370d2c601f7d33696ff3f30fb77aa72e", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "SRR10566631", "url": "https://sra-pub-run-odp.s3.amazonaws.com/sra/SRR10566631/SRR10566631", "size": "19967659436", "date": "2019-12-01 09:33:04", "md5": "8add01f781a5f2031a9b883804875002", "version": "1", "semantic_name": "SRA Normalized", "supertype": "Primary ETL", "sratoolkit": "1"}}, {"Alternatives": [null, null, null], "@attributes": {"cluster": "public", "filename": "SRR10566631.lite", "url": "https://sra-downloadb.be-md.ncbi.nlm.nih.gov/sos5/sra-pub-zq-16/SRR010/10566/SRR10566631/SRR10566631.lite.1", "size": "9811510733", "date": "2022-06-24 04:18:56", "md5": "ef6eac41368986552d440128eafa19fe", "version": "1", "semantic_name": "SRA Lite", "supertype": "Primary ETL", "sratoolkit": "1"}}]