EXPERIMENT_TITLE: GSM4198750: BLaER cell line, 72h_HiC_rep1; Homo sapiens; Hi-C
EXPERIMENT_DESIGN_LIBRARY_DESCRIPTOR_LIBRARY_CONSTRUCTION_PROTOC: Cells were collected by centrifugation. Crosslinked nuclei were digested with MboI followed by fill-in with bio-dATP, in-situ ligation and DNA extraction. DNA was sonicated and libraries were constructed using the the NEBNext DNA Library Prep Kit (New England Biolabs).
STUDY_DESCRIPTOR_STUDY_ABSTRACT: Studies of genome topology, chromatin state and gene expression dynamic during human B cell to macrophage transdifferentiation with and without CTCF Overall design: Genome topology profiling during  human B cell to macrophage transdifferentiation with and without CTCF using insitu HiC
SAMPLE_TITLE: BLaER cell line, 72h_HiC_rep1
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "source_name", "VALUE": "Leukemia cell line"}, {"TAG": "cell line", "VALUE": "BLaER"}, {"TAG": "treatment", "VALUE": "CEBPA"}, {"TAG": "time", "VALUE": "72h"}]
Pool_Member_@attributes_sample_title: BLaER cell line, 72h_HiC_rep1
RUN_SET_RUN_Pool_Member_@attributes_sample_title: BLaER cell line, 72h_HiC_rep1
RUN_SET_RUN_SRAFiles_SRAFile: [{"Alternatives": null, "@attributes": {"cluster": "public", "filename": "909108526_eb5e1b9ac_read1.fastq.gz", "size": "15941423503", "date": "2019-12-01 09:37:07", "md5": "a0ebfe4cd65419422c09cdee63a49538", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "909108526_eb5e1b9ac_read2.fastq.gz", "size": "16411229614", "date": "2019-12-01 09:41:49", "md5": "84ae2d3444441d499021c755f4b56b7a", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "SRR10566612", "url": "https://sra-pub-run-odp.s3.amazonaws.com/sra/SRR10566612/SRR10566612", "size": "20298956952", "date": "2019-12-01 09:52:04", "md5": "2a5a5c4b019f95d1fad2cce4e008ced6", "version": "1", "semantic_name": "SRA Normalized", "supertype": "Primary ETL", "sratoolkit": "1"}}, {"Alternatives": [null, null, null], "@attributes": {"cluster": "public", "filename": "SRR10566612.sralite", "url": "https://sra-downloadb.be-md.ncbi.nlm.nih.gov/sos3/sra-pub-zq-22/SRR010/566/SRR10566612.sralite.1", "size": "11568352844", "date": "2020-06-19 21:42:02", "md5": "130ea67a16ec6e25ef0c30eeac7db0d0", "version": "1", "semantic_name": "SRA Lite", "supertype": "Primary ETL", "sratoolkit": "1"}}]