EXPERIMENT_TITLE: GSM4198752: BLaER cell line, 120h_HiC_rep1; Homo sapiens; Hi-C
EXPERIMENT_DESIGN_LIBRARY_DESCRIPTOR_LIBRARY_CONSTRUCTION_PROTOC: Cells were collected by centrifugation. Crosslinked nuclei were digested with MboI followed by fill-in with bio-dATP, in-situ ligation and DNA extraction. DNA was sonicated and libraries were constructed using the the NEBNext DNA Library Prep Kit (New England Biolabs).
STUDY_DESCRIPTOR_STUDY_ABSTRACT: Studies of genome topology, chromatin state and gene expression dynamic during human B cell to macrophage transdifferentiation with and without CTCF Overall design: Genome topology profiling during  human B cell to macrophage transdifferentiation with and without CTCF using insitu HiC
SAMPLE_TITLE: BLaER cell line, 120h_HiC_rep1
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "source_name", "VALUE": "Leukemia cell line"}, {"TAG": "cell line", "VALUE": "BLaER"}, {"TAG": "treatment", "VALUE": "CEBPA"}, {"TAG": "time", "VALUE": "120h"}]
Pool_Member_@attributes_sample_title: BLaER cell line, 120h_HiC_rep1
RUN_SET_RUN_Pool_Member_@attributes_sample_title: BLaER cell line, 120h_HiC_rep1
RUN_SET_RUN_SRAFiles_SRAFile: [{"Alternatives": null, "@attributes": {"cluster": "public", "filename": "c414d617a_eb5e1b9ac_read1.fastq.gz", "size": "15672773168", "date": "2019-12-01 09:45:50", "md5": "b27dbab91c53d279484ba899f187e783", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "c414d617a_eb5e1b9ac_read2.fastq.gz", "size": "16071936020", "date": "2019-12-01 09:51:15", "md5": "9869fa7bfcd267e6167078516d67fd91", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "SRR10566614", "url": "https://sra-pub-run-odp.s3.amazonaws.com/sra/SRR10566614/SRR10566614", "size": "19932187914", "date": "2019-12-01 10:04:36", "md5": "52a02b16bafe5e87ebf2e21ac9863819", "version": "1", "semantic_name": "SRA Normalized", "supertype": "Primary ETL", "sratoolkit": "1"}}, {"Alternatives": [null, null, null], "@attributes": {"cluster": "public", "filename": "SRR10566614.sralite", "url": "https://sra-downloadb.be-md.ncbi.nlm.nih.gov/sos3/sra-pub-zq-22/SRR010/566/SRR10566614.sralite.1", "size": "11347022726", "date": "2020-06-22 19:57:31", "md5": "f9aa6efc29ac01356ad50e07d8d4b70c", "version": "1", "semantic_name": "SRA Lite", "supertype": "Primary ETL", "sratoolkit": "1"}}]