EXPERIMENT_TITLE: GSM2827786: CD4+ T cells 1; Homo sapiens; Hi-C
EXPERIMENT_DESIGN_LIBRARY_DESCRIPTOR_LIBRARY_CONSTRUCTION_PROTOC: As outlined in Rao et al, Cell, 2014 In situ HiC was performed as previously published (Rao et al, Cell, 2014). Libraries were generated in biological duplicate.
STUDY_DESCRIPTOR_STUDY_ABSTRACT: Over recent decades, it has been proposed that DNA interactions between mammalian chromosomes play an important role in the regulation of gene expression and cell fate determination. To study how DNA interactions change between cell types, high throughput chromosome confirmation capture (Hi-C) profiles were collected from CD4+ T cells, CD8+ T cells and B cells from human subjects. Overall design: In situ HiC was performed separately on three cell types (CD4+ T cells, CD8+ T cells and B cells) from two male human subjects.
SAMPLE_TITLE: CD4+ T cells 1
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "source_name", "VALUE": "Na\u00efve CD4+ T cells"}, {"TAG": "subject", "VALUE": "1"}, {"TAG": "tissue", "VALUE": "Peripheral blood"}, {"TAG": "cell type", "VALUE": "T lymphocytes"}]
Pool_Member_@attributes_sample_title: CD4+ T cells 1
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