EXPERIMENT_TITLE: GSM8323377: R1881; Homo sapiens; Hi-C
EXPERIMENT_DESIGN_LIBRARY_DESCRIPTOR_LIBRARY_CONSTRUCTION_PROTOC: DNA were extracted using Arima Genomics HiC kit Hi-C-library preparation
STUDY_DESCRIPTOR_STUDY_ABSTRACT: This study investigates the role of noncoding RNAs in resistance to the anti-androgen drug daro-lutamide in prostate cancer. RNA sequencing identified LOC730101 as a significantly elevated lncRNA in darolutamide-resistant cells. Silencing LOC730101 reduced cell proliferation, indicating its role in drug resistance. Overall design: To investigate the lncRNA function in DaroR resistant cells
SAMPLE_TITLE: R1881
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "source_name", "VALUE": "Prostate cancer"}, {"TAG": "tissue", "VALUE": "Prostate cancer"}, {"TAG": "cell line", "VALUE": "LNCaP"}, {"TAG": "cell type", "VALUE": "hormone sensitive prostate cancer"}, {"TAG": "genotype", "VALUE": "Drug treated"}, {"TAG": "treatment", "VALUE": "1nM R1881"}, {"TAG": "geo_loc_name", "VALUE": "missing"}, {"TAG": "collection_date", "VALUE": "missing"}]
Pool_Member_@attributes_sample_title: R1881
RUN_SET_RUN_Pool_Member_@attributes_sample_title: R1881
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