EXPERIMENT_TITLE: GSM4198748: BLaER cell line, 24h_HiC_rep1; Homo sapiens; Hi-C
EXPERIMENT_DESIGN_LIBRARY_DESCRIPTOR_LIBRARY_CONSTRUCTION_PROTOC: Cells were collected by centrifugation. Crosslinked nuclei were digested with MboI followed by fill-in with bio-dATP, in-situ ligation and DNA extraction. DNA was sonicated and libraries were constructed using the the NEBNext DNA Library Prep Kit (New England Biolabs).
STUDY_DESCRIPTOR_STUDY_ABSTRACT: Studies of genome topology, chromatin state and gene expression dynamic during human B cell to macrophage transdifferentiation with and without CTCF Overall design: Genome topology profiling during  human B cell to macrophage transdifferentiation with and without CTCF using insitu HiC
SAMPLE_TITLE: BLaER cell line, 24h_HiC_rep1
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "source_name", "VALUE": "Leukemia cell line"}, {"TAG": "cell line", "VALUE": "BLaER"}, {"TAG": "treatment", "VALUE": "CEBPA"}, {"TAG": "time", "VALUE": "24h"}]
Pool_Member_@attributes_sample_title: BLaER cell line, 24h_HiC_rep1
RUN_SET_RUN_Pool_Member_@attributes_sample_title: BLaER cell line, 24h_HiC_rep1
RUN_SET_RUN_SRAFiles_SRAFile: [{"Alternatives": null, "@attributes": {"cluster": "public", "filename": "dea3f4c39_eb5e1b9ac_read1.fastq.gz", "size": "15745245037", "date": "2019-12-01 09:37:30", "md5": "34b3f6fcd4e0bdc0e8fd43fc89d37076", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "dea3f4c39_eb5e1b9ac_read2.fastq.gz", "size": "16133580794", "date": "2019-12-01 09:42:55", "md5": "e02e52bd6bc7ff5a10611328c78eb0ac", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "SRR10566610", "url": "https://sra-pub-run-odp.s3.amazonaws.com/sra/SRR10566610/SRR10566610", "size": "20022185482", "date": "2019-12-01 09:55:33", "md5": "53e3fb50bb48bf04b86067b94cc8b16a", "version": "1", "semantic_name": "SRA Normalized", "supertype": "Primary ETL", "sratoolkit": "1"}}, {"Alternatives": [null, null, null], "@attributes": {"cluster": "public", "filename": "SRR10566610.lite", "url": "https://sra-downloadb.be-md.ncbi.nlm.nih.gov/sos5/sra-pub-zq-16/SRR010/10566/SRR10566610/SRR10566610.lite.1", "size": "11377684226", "date": "2022-06-24 03:33:43", "md5": "f67057be1f0a0d05fba5d463943954c8", "version": "1", "semantic_name": "SRA Lite", "supertype": "Primary ETL", "sratoolkit": "1"}}]