EXPERIMENT_TITLE: GSM4198763: BLaER cell line, 144h_HiC_rep2; Homo sapiens; Hi-C
EXPERIMENT_DESIGN_LIBRARY_DESCRIPTOR_LIBRARY_CONSTRUCTION_PROTOC: Cells were collected by centrifugation. Crosslinked nuclei were digested with MboI followed by fill-in with bio-dATP, in-situ ligation and DNA extraction. DNA was sonicated and libraries were constructed using the the NEBNext DNA Library Prep Kit (New England Biolabs).
STUDY_DESCRIPTOR_STUDY_ABSTRACT: Studies of genome topology, chromatin state and gene expression dynamic during human B cell to macrophage transdifferentiation with and without CTCF Overall design: Genome topology profiling during  human B cell to macrophage transdifferentiation with and without CTCF using insitu HiC
SAMPLE_TITLE: BLaER cell line, 144h_HiC_rep2
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "source_name", "VALUE": "Leukemia cell line"}, {"TAG": "cell line", "VALUE": "BLaER"}, {"TAG": "treatment", "VALUE": "CEBPA"}, {"TAG": "time", "VALUE": "144h"}]
Pool_Member_@attributes_sample_title: BLaER cell line, 144h_HiC_rep2
RUN_SET_RUN_Pool_Member_@attributes_sample_title: BLaER cell line, 144h_HiC_rep2
RUN_SET_RUN_SRAFiles_SRAFile: [{"Alternatives": [null, null, null], "@attributes": {"cluster": "public", "filename": "SRR10566625.sralite", "url": "https://sra-downloadb.be-md.ncbi.nlm.nih.gov/sos3/sra-pub-zq-22/SRR010/566/SRR10566625.sralite.1", "size": "10299689030", "date": "2020-06-24 01:59:39", "md5": "aa43bcaf6b58fe087f0803abd087a7e8", "version": "1", "semantic_name": "SRA Lite", "supertype": "Primary ETL", "sratoolkit": "1"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "SRR10566625", "url": "https://sra-pub-run-odp.s3.amazonaws.com/sra/SRR10566625/SRR10566625", "size": "14351200014", "date": "2019-12-01 10:39:31", "md5": "bad16606d57426920e51035d16d2e1cd", "version": "1", "semantic_name": "SRA Normalized", "supertype": "Primary ETL", "sratoolkit": "1"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "1c0ccd992_28b772509_read2.fastq.gz", "size": "10811227755", "date": "2019-12-01 10:32:30", "md5": "0220533339a5713aad1d2b497fbcd3b4", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "1c0ccd992_28b772509_read1.fastq.gz", "size": "10426700110", "date": "2019-12-01 10:28:05", "md5": "9363aadf393c02cb81395f74c2b57f8c", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}]