EXPERIMENT_TITLE: GSM4198751: BLaER cell line, 96h_HiC_rep1; Homo sapiens; Hi-C
EXPERIMENT_DESIGN_LIBRARY_DESCRIPTOR_LIBRARY_CONSTRUCTION_PROTOC: Cells were collected by centrifugation. Crosslinked nuclei were digested with MboI followed by fill-in with bio-dATP, in-situ ligation and DNA extraction. DNA was sonicated and libraries were constructed using the the NEBNext DNA Library Prep Kit (New England Biolabs).
STUDY_DESCRIPTOR_STUDY_ABSTRACT: Studies of genome topology, chromatin state and gene expression dynamic during human B cell to macrophage transdifferentiation with and without CTCF Overall design: Genome topology profiling during  human B cell to macrophage transdifferentiation with and without CTCF using insitu HiC
SAMPLE_TITLE: BLaER cell line, 96h_HiC_rep1
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "source_name", "VALUE": "Leukemia cell line"}, {"TAG": "cell line", "VALUE": "BLaER"}, {"TAG": "treatment", "VALUE": "CEBPA"}, {"TAG": "time", "VALUE": "96h"}]
Pool_Member_@attributes_sample_title: BLaER cell line, 96h_HiC_rep1
RUN_SET_RUN_Pool_Member_@attributes_sample_title: BLaER cell line, 96h_HiC_rep1
RUN_SET_RUN_SRAFiles_SRAFile: [{"Alternatives": null, "@attributes": {"cluster": "public", "filename": "e0197e442_eb5e1b9ac_read1.fastq.gz", "size": "17566571618", "date": "2019-12-01 09:32:18", "md5": "ca4cb90e2e0d5daf7815f49b427ddcac", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "e0197e442_eb5e1b9ac_read2.fastq.gz", "size": "18134630610", "date": "2019-12-01 09:47:09", "md5": "101305973e99011d58cad0b5af9c892b", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "SRR10566613", "url": "https://sra-pub-run-odp.s3.amazonaws.com/sra/SRR10566613/SRR10566613", "size": "22630934544", "date": "2019-12-01 10:05:19", "md5": "d8ac87493c03af80dd968886674d4c15", "version": "1", "semantic_name": "SRA Normalized", "supertype": "Primary ETL", "sratoolkit": "1"}}, {"Alternatives": [null, null, null], "@attributes": {"cluster": "public", "filename": "SRR10566613.sralite", "url": "https://sra-downloadb.be-md.ncbi.nlm.nih.gov/sos5/sra-pub-zq-11/SRR010/566/SRR10566613/SRR10566613.sralite.1", "size": "12360722384", "date": "2020-06-22 14:00:41", "md5": "65d9716fe8bb9495d5006a5a6edce6c6", "version": "1", "semantic_name": "SRA Lite", "supertype": "Primary ETL", "sratoolkit": "1"}}]