EXPERIMENT_TITLE: Hi-C of Sample 3 - I
STUDY_DESCRIPTOR_STUDY_ABSTRACT: The overarching goal of the study was to better understand the evolution of melanoma. To do this, we collected archival tissue of melanomas adjacent to their intact, remnant precursor lesions. We also collected archival tissue of primary melanomas and their matching metastases. From the formalin-fixed paraffin-embedded (FFPE) blocks, we microdissected non-neoplastic (normal), precursor, and descendent portions of tissue. Both RNA and DNA were extracted from the microdissected tissues and subjected to next generation sequencing. In summary, we performed matched DNA/RNA sequencing of melanoma/precursor/normal trios, allowing us to trace the genetic and transcriptomic evolution of melanoma.
SAMPLE_TITLE: Melanoma tumor DNA sample from unknown of a human female participant in the dbGaP study "The Genetic and Transcriptomic Evolution of Melanoma"
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "gap_accession", "VALUE": "phs001550"}, {"TAG": "submitter handle", "VALUE": "NCI_MelanocyticNeoplasms"}, {"TAG": "biospecimen repository", "VALUE": "NCI_MelanocyticNeoplasms"}, {"TAG": "study name", "VALUE": "The Genetic and Transcriptomic Evolution of Melanoma"}, {"TAG": "study design", "VALUE": "Tumor vs. Matched-Normal"}, {"TAG": "biospecimen repository sample id", "VALUE": "58_CT432_Hi-C"}, {"TAG": "submitted sample id", "VALUE": "58_CT432_Hi-C"}, {"TAG": "submitted subject id", "VALUE": "58"}, {"TAG": "gap_sample_id", "VALUE": "5051420"}, {"TAG": "gap_subject_id", "VALUE": "2446863"}, {"TAG": "sex", "VALUE": "female"}, {"TAG": "study disease", "VALUE": "Melanoma"}, {"TAG": "body site", "VALUE": "unknown"}, {"TAG": "histological type", "VALUE": "Melanoma"}, {"TAG": "analyte type", "VALUE": "DNA"}, {"TAG": "is tumor", "VALUE": "Yes"}, {"TAG": "subject is affected", "VALUE": "Yes"}, {"TAG": "gap_consent_code", "VALUE": "1"}, {"TAG": "gap_consent_short_name", "VALUE": "DS-M-NPU"}]
Pool_Member_@attributes_sample_title: Melanoma tumor DNA sample from unknown of a human female participant in the dbGaP study "The Genetic and Transcriptomic Evolution of Melanoma"
RUN_SET_RUN_Pool_Member_@attributes_sample_title: Melanoma tumor DNA sample from unknown of a human female participant in the dbGaP study "The Genetic and Transcriptomic Evolution of Melanoma"