EXPERIMENT_TITLE: GSM4198773: BLaER subclone, 168h_CTCF_AID_AUX_HiC_rep2; Homo sapiens; Hi-C
EXPERIMENT_DESIGN_LIBRARY_DESCRIPTOR_LIBRARY_CONSTRUCTION_PROTOC: Cells were collected by centrifugation. Crosslinked nuclei were digested with MboI followed by fill-in with bio-dATP, in-situ ligation and DNA extraction. DNA was sonicated and libraries were constructed using the the NEBNext DNA Library Prep Kit (New England Biolabs).
STUDY_DESCRIPTOR_STUDY_ABSTRACT: Studies of genome topology, chromatin state and gene expression dynamic during human B cell to macrophage transdifferentiation with and without CTCF Overall design: Genome topology profiling during  human B cell to macrophage transdifferentiation with and without CTCF using insitu HiC
SAMPLE_TITLE: BLaER subclone, 168h_CTCF_AID_AUX_HiC_rep2
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "source_name", "VALUE": "Leukemia cell line"}, {"TAG": "subclone", "VALUE": "BLaER subclone CTCF-AID (Auxin Inducible Degron)"}, {"TAG": "treatment", "VALUE": "CEBPA+auxin"}, {"TAG": "time", "VALUE": "168h"}]
Pool_Member_@attributes_sample_title: BLaER subclone, 168h_CTCF_AID_AUX_HiC_rep2
RUN_SET_RUN_Pool_Member_@attributes_sample_title: BLaER subclone, 168h_CTCF_AID_AUX_HiC_rep2
RUN_SET_RUN_SRAFiles_SRAFile: [{"Alternatives": [null, null, null], "@attributes": {"cluster": "public", "filename": "SRR10566635.sralite", "url": "https://sra-downloadb.be-md.ncbi.nlm.nih.gov/sos3/sra-pub-zq-22/SRR010/566/SRR10566635.sralite.1", "size": "9823802912", "date": "2020-06-21 14:35:32", "md5": "ec31c30ba4cf43be855ef4256d469bdc", "version": "1", "semantic_name": "SRA Lite", "supertype": "Primary ETL", "sratoolkit": "1"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "SRR10566635", "url": "https://sra-pub-run-odp.s3.amazonaws.com/sra/SRR10566635/SRR10566635", "size": "19867092328", "date": "2019-12-01 09:55:23", "md5": "b2f0193cc3bc08332cf6ba8d976388d2", "version": "1", "semantic_name": "SRA Normalized", "supertype": "Primary ETL", "sratoolkit": "1"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "462beb444_8b15391e7_read2.fastq.gz", "size": "15636888308", "date": "2019-12-01 09:41:57", "md5": "e740ba5d701f7a6252786096e63ce570", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "462beb444_8b15391e7_read1.fastq.gz", "size": "15117831501", "date": "2019-12-01 09:33:11", "md5": "7ca8b07df4b35591b3db98c5c2339ec1", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}]