EXPERIMENT_TITLE: GSM4198764: BLaER cell line, 168h_HiC_rep2; Homo sapiens; Hi-C
EXPERIMENT_DESIGN_LIBRARY_DESCRIPTOR_LIBRARY_CONSTRUCTION_PROTOC: Cells were collected by centrifugation. Crosslinked nuclei were digested with MboI followed by fill-in with bio-dATP, in-situ ligation and DNA extraction. DNA was sonicated and libraries were constructed using the the NEBNext DNA Library Prep Kit (New England Biolabs).
STUDY_DESCRIPTOR_STUDY_ABSTRACT: Studies of genome topology, chromatin state and gene expression dynamic during human B cell to macrophage transdifferentiation with and without CTCF Overall design: Genome topology profiling during  human B cell to macrophage transdifferentiation with and without CTCF using insitu HiC
SAMPLE_TITLE: BLaER cell line, 168h_HiC_rep2
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "source_name", "VALUE": "Leukemia cell line"}, {"TAG": "cell line", "VALUE": "BLaER"}, {"TAG": "treatment", "VALUE": "CEBPA"}, {"TAG": "time", "VALUE": "168h"}]
Pool_Member_@attributes_sample_title: BLaER cell line, 168h_HiC_rep2
RUN_SET_RUN_Pool_Member_@attributes_sample_title: BLaER cell line, 168h_HiC_rep2
RUN_SET_RUN_SRAFiles_SRAFile: [{"Alternatives": [null, null, null], "@attributes": {"cluster": "public", "filename": "SRR10566626.sralite", "url": "https://sra-downloadb.be-md.ncbi.nlm.nih.gov/sos5/sra-pub-zq-11/SRR010/566/SRR10566626/SRR10566626.sralite.1", "size": "9538059118", "date": "2020-06-19 20:45:13", "md5": "a39a77bb91a8ba7a2bf46816cafcaa77", "version": "1", "semantic_name": "SRA Lite", "supertype": "Primary ETL", "sratoolkit": "1"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "SRR10566626", "url": "https://sra-pub-run-odp.s3.amazonaws.com/sra/SRR10566626/SRR10566626", "size": "13255452610", "date": "2019-12-01 11:01:37", "md5": "b5a8c640974d04e64ddb6c472cfd20c7", "version": "1", "semantic_name": "SRA Normalized", "supertype": "Primary ETL", "sratoolkit": "1"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "a22b78cba_28b772509_read2.fastq.gz", "size": "10016799290", "date": "2019-12-01 10:56:56", "md5": "2f136b7dfcc7952693704c98db9a9406", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "a22b78cba_28b772509_read1.fastq.gz", "size": "9702916203", "date": "2019-12-01 10:53:59", "md5": "1b0e149da1b938606c3bf4f0b91230dc", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}]