EXPERIMENT_TITLE: Hi-C of homo sapiens (human) liver cells (PHH) of patient 342, Non infected (BC180), replicate 1
STUDY_DESCRIPTOR_STUDY_ABSTRACT: Whether non-integrated viral DNAs distribute randomly or target specific positions within the higher-order architecture of mammalian genomes remains largely unknown. We used Hi-C and viral DNA capture (CHi-C) in primary human hepatocytes infected by either hepatitis B virus (HBV) or adenovirus type 5 (Ad5) virus to show that they adopt different strategies in their respective positioning at active chromatin.
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "isolate", "VALUE": "PHH_342"}, {"TAG": "age", "VALUE": "2 years"}, {"TAG": "biomaterial_provider", "VALUE": "Corning (reference 454541, lot #342)"}, {"TAG": "sex", "VALUE": "female"}, {"TAG": "tissue", "VALUE": "liver"}, {"TAG": "cell_type", "VALUE": "PHH"}, {"TAG": "disease", "VALUE": "Non infected with HBV"}, {"TAG": "ethnicity", "VALUE": "caucasian"}, {"TAG": "treatment", "VALUE": "Hi-C without Capture"}, {"TAG": "replicate", "VALUE": "biological replicate 1"}, {"TAG": "BioSampleModel", "VALUE": "Human"}]
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