EXPERIMENT_TITLE: GSM4198771: BLaER subclone, 24h_CTCF_AID_AUX_HiC_rep2; Homo sapiens; Hi-C
EXPERIMENT_DESIGN_LIBRARY_DESCRIPTOR_LIBRARY_CONSTRUCTION_PROTOC: Cells were collected by centrifugation. Crosslinked nuclei were digested with MboI followed by fill-in with bio-dATP, in-situ ligation and DNA extraction. DNA was sonicated and libraries were constructed using the the NEBNext DNA Library Prep Kit (New England Biolabs).
STUDY_DESCRIPTOR_STUDY_ABSTRACT: Studies of genome topology, chromatin state and gene expression dynamic during human B cell to macrophage transdifferentiation with and without CTCF Overall design: Genome topology profiling during  human B cell to macrophage transdifferentiation with and without CTCF using insitu HiC
SAMPLE_TITLE: BLaER subclone, 24h_CTCF_AID_AUX_HiC_rep2
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "source_name", "VALUE": "Leukemia cell line"}, {"TAG": "subclone", "VALUE": "BLaER subclone CTCF-AID (Auxin Inducible Degron)"}, {"TAG": "treatment", "VALUE": "CEBPA+DMSO"}, {"TAG": "time", "VALUE": "168h"}]
Pool_Member_@attributes_sample_title: BLaER subclone, 24h_CTCF_AID_AUX_HiC_rep2
RUN_SET_RUN_Pool_Member_@attributes_sample_title: BLaER subclone, 24h_CTCF_AID_AUX_HiC_rep2
RUN_SET_RUN_SRAFiles_SRAFile: [{"Alternatives": null, "@attributes": {"cluster": "public", "filename": "47def1baf_8b15391e7_read1.fastq.gz", "size": "15089646817", "date": "2019-12-01 09:33:25", "md5": "be35ac76e636873439f1d30cf4230331", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "47def1baf_8b15391e7_read2.fastq.gz", "size": "15410279375", "date": "2019-12-01 09:37:48", "md5": "82c8b764aad94096f694e750bc9c1daf", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "SRR10566633", "url": "https://sra-pub-run-odp.s3.amazonaws.com/sra/SRR10566633/SRR10566633", "size": "19747348784", "date": "2019-12-01 09:47:15", "md5": "6ab6c1ee045a07d80306d1b289238623", "version": "1", "semantic_name": "SRA Normalized", "supertype": "Primary ETL", "sratoolkit": "1"}}, {"Alternatives": [null, null, null], "@attributes": {"cluster": "public", "filename": "SRR10566633.sralite", "url": "https://sra-downloadb.be-md.ncbi.nlm.nih.gov/sos3/sra-pub-zq-22/SRR010/566/SRR10566633.sralite.1", "size": "9657814763", "date": "2020-06-19 21:22:58", "md5": "2909945879f60423b86e95b73109f2f7", "version": "1", "semantic_name": "SRA Lite", "supertype": "Primary ETL", "sratoolkit": "1"}}]