EXPERIMENT_TITLE: unknown
STUDY_DESCRIPTOR_STUDY_ABSTRACT: We analyzed the de novo rare variants in new COS cases by Whole exome sequencing (WES) and try to find out the probable COS candidate genes. We measured the rate of de novo variants (DNVs) and used WGCNA to construct a network of coexpressed genes, we also checed differential DNA methylation between COS Disease groups, COS Dangerous groups, and Normal groups.
SAMPLE_TITLE: unknown
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "isolate", "VALUE": "GSZ043"}, {"TAG": "age", "VALUE": "14"}, {"TAG": "biomaterial_provider", "VALUE": "Yuhang Cheng, Beijing Anding Hospital"}, {"TAG": "sex", "VALUE": "not collected"}, {"TAG": "tissue", "VALUE": "blood"}, {"TAG": "BioSampleModel", "VALUE": "Human"}]
Pool_Member_@attributes_sample_title: unknown
RUN_SET_RUN_Pool_Member_@attributes_sample_title: unknown
RUN_SET_RUN_SRAFiles_SRAFile: [{"Alternatives": null, "@attributes": {"cluster": "public", "filename": "GSZ043_R1.fastq.gz", "size": "4328308597", "date": "2022-04-20 03:46:14", "md5": "e6885e45a1d0a0ec216864fac7b4899a", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "GSZ043_R2.fastq.gz", "size": "4564824916", "date": "2022-04-20 03:46:28", "md5": "a150ebcf9ddb2dbd83a29fe3b9580bb4", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "SRR18828042", "url": "https://sra-pub-run-odp.s3.amazonaws.com/sra/SRR18828042/SRR18828042", "size": "6108222364", "date": "2022-04-20 03:47:41", "md5": "60381e3c8e738f4e1993782572162a83", "version": "1", "semantic_name": "SRA Normalized", "supertype": "Primary ETL", "sratoolkit": "1"}}, {"Alternatives": [null, null, null], "@attributes": {"cluster": "public", "filename": "SRR18828042.lite", "url": "https://sra-downloadb.be-md.ncbi.nlm.nih.gov/sos2/sra-pub-zq-18/SRR018/18828/SRR18828042/SRR18828042.lite.1", "size": "3927288972", "date": "2022-10-24 23:21:00", "md5": "5753bffb09b12a624195d37273713be2", "version": "1", "semantic_name": "SRA Lite", "supertype": "Primary ETL", "sratoolkit": "1"}}]