EXPERIMENT_TITLE: GSM7825116: Hi-C of subject 1, term not in labor; Homo sapiens; Hi-C
EXPERIMENT_DESIGN_LIBRARY_DESCRIPTOR_LIBRARY_CONSTRUCTION_PROTOC: by Arima Genomics and Active Motif
STUDY_DESCRIPTOR_STUDY_ABSTRACT: Timely control of parturition is crucial for maternal and fetal health. Failures on this biological process often result in pregnancy complications including preterm birth, labor dystocia, and health disorders on newborn babies. The myometrium is the muscular structure of the uterus maintaining uterine structural integrity and providing contractile force for parturition. The myometrial structure changes in adaptation to the pregnancy via stage-specific transcriptomic profiles. Data from the mouse model indicate that changes of myometrial epigenomic landscape precedes the adoption of stage-specific gene expression pattern at term. The present study documents the chromatin interaction profiles in the term pregnant not in labor human myometrial tissues at a genome-wide scale. Overall design: Term pregnant not in labor (TNL) human myometrial specimens from two healthy individuals were subject to the Hi-C assay to profile the genome-wide chromatin interactions.
SAMPLE_TITLE: Hi-C of subject 1, term not in labor
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "source_name", "VALUE": "Myometrium"}, {"TAG": "Stage", "VALUE": "Term not in labor"}, {"TAG": "tissue", "VALUE": "Myometrium"}, {"TAG": "geo_loc_name", "VALUE": "missing"}, {"TAG": "collection_date", "VALUE": "missing"}]
Pool_Member_@attributes_sample_title: Hi-C of subject 1, term not in labor
RUN_SET_RUN_Pool_Member_@attributes_sample_title: Hi-C of subject 1, term not in labor
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