EXPERIMENT_TITLE: Illumina HiSeq 4000 paired end sequencing; 4C-seq at iHUB regions in L3.6pl
EXPERIMENT_DESIGN_LIBRARY_DESCRIPTOR_LIBRARY_CONSTRUCTION_PROTOC: 8 million cells were treated for 4 hours with vehicle or VIP152 (CDK9i). Then cells were trypsinized and crosslinked using 2% Formaldehyde for 10 minutes. Phenol/Chloroform DNA extraction Libraries were performed as described in Krijger et al
STUDY_DESCRIPTOR_STUDY_ABSTRACT: Evaluation of interaction frequency in parental L3.6pl cells, paclitaxel-resistant cells and resistant cells treated with a CDK9 inhibitor
SAMPLE_TITLE: GPX4 iHUB PacR CDK9i
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "ENA-FIRST-PUBLIC", "VALUE": "2023-01-01"}, {"TAG": "ENA-LAST-UPDATE", "VALUE": "2023-01-01"}, {"TAG": "External Id", "VALUE": "SAMEA14382062"}, {"TAG": "INSDC center alias", "VALUE": "Mayo Clinic"}, {"TAG": "INSDC center name", "VALUE": "Mayo Clinic"}, {"TAG": "INSDC first public", "VALUE": "2023-01-01T00:28:00Z"}, {"TAG": "INSDC last update", "VALUE": "2023-01-01T00:28:00Z"}, {"TAG": "INSDC status", "VALUE": "public"}, {"TAG": "Submitter Id", "VALUE": "E-MTAB-11731:GPX4 iHUB PacR CDK9i"}, {"TAG": "broker name", "VALUE": "ArrayExpress"}, {"TAG": "cell_line", "VALUE": "L3.6pl"}, {"TAG": "common name", "VALUE": "human"}, {"TAG": "developmental stage", "VALUE": "adult"}, {"TAG": "disease", "VALUE": "pancreatic adenosquamous carcinoma"}, {"TAG": "genotype", "VALUE": "wild type genotype"}, {"TAG": "isolate", "VALUE": "not applicable"}, {"TAG": "organism part", "VALUE": "pancreatic duct"}, {"TAG": "phenotype", "VALUE": "paclitaxel resistant"}, {"TAG": "sample name", "VALUE": "E-MTAB-11731:GPX4 iHUB PacR CDK9i"}, {"TAG": "sampling site", "VALUE": "cceliac lymph node"}]
Pool_Member_@attributes_sample_title: GPX4 iHUB PacR CDK9i
RUN_SET_RUN_Pool_Member_@attributes_sample_title: GPX4 iHUB PacR CDK9i
RUN_SET_RUN_SRAFiles_SRAFile: [{"Alternatives": null, "@attributes": {"cluster": "public", "filename": "PacR_BAY_GPX4_iHUB.FCHLLKMBBXY_L4_R1_IATTCCT.fastq.gz", "size": "310169992", "date": "2023-01-10 04:00:57", "md5": "ba1cf60d6bf1274c7c38907833ee6130", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "PacR_BAY_GPX4_iHUB.FCHLLKMBBXY_L4_R2_IATTCCT.fastq.gz", "size": "125773102", "date": "2023-01-10 04:01:00", "md5": "ad56c32bd17fc86d9a667ff114e3890a", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "ERR9723976", "url": "https://sra-pub-run-odp.s3.amazonaws.com/sra/ERR9723976/ERR9723976", "size": "445235270", "date": "2023-01-10 04:01:12", "md5": "eb447950f7e8ba21efcbdef6d6a3e18d", "version": "1", "semantic_name": "SRA Normalized", "supertype": "Primary ETL", "sratoolkit": "1"}}, {"Alternatives": [null, null, null], "@attributes": {"cluster": "public", "filename": "ERR9723976.lite", "url": "https://sra-downloadb.be-md.ncbi.nlm.nih.gov/sos2/sra-pub-zq-20/ERR009/9723/ERR9723976/ERR9723976.lite.1", "size": "245379506", "date": "2023-01-10 04:28:41", "md5": "5262ada016f439d641ba8e4d3c76fd76", "version": "1", "semantic_name": "SRA Lite", "supertype": "Primary ETL", "sratoolkit": "1"}}]