EXPERIMENT_TITLE: GSM4198757: BLaER cell line, 18h_HiC_rep2; Homo sapiens; Hi-C
EXPERIMENT_DESIGN_LIBRARY_DESCRIPTOR_LIBRARY_CONSTRUCTION_PROTOC: Cells were collected by centrifugation. Crosslinked nuclei were digested with MboI followed by fill-in with bio-dATP, in-situ ligation and DNA extraction. DNA was sonicated and libraries were constructed using the the NEBNext DNA Library Prep Kit (New England Biolabs).
STUDY_DESCRIPTOR_STUDY_ABSTRACT: Studies of genome topology, chromatin state and gene expression dynamic during human B cell to macrophage transdifferentiation with and without CTCF Overall design: Genome topology profiling during  human B cell to macrophage transdifferentiation with and without CTCF using insitu HiC
SAMPLE_TITLE: BLaER cell line, 18h_HiC_rep2
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "source_name", "VALUE": "Leukemia cell line"}, {"TAG": "cell line", "VALUE": "BLaER"}, {"TAG": "treatment", "VALUE": "CEBPA"}, {"TAG": "time", "VALUE": "18h"}]
Pool_Member_@attributes_sample_title: BLaER cell line, 18h_HiC_rep2
RUN_SET_RUN_Pool_Member_@attributes_sample_title: BLaER cell line, 18h_HiC_rep2
RUN_SET_RUN_SRAFiles_SRAFile: [{"Alternatives": null, "@attributes": {"cluster": "public", "filename": "c05ab57b8_28b772509_read1.fastq.gz", "size": "8299675392", "date": "2019-12-01 10:10:29", "md5": "cdec7b48579d7d24abf839521103bb05", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "c05ab57b8_28b772509_read2.fastq.gz", "size": "8521376915", "date": "2019-12-01 10:18:45", "md5": "ed0a016e47388162f0ddcc2ea6b0fab0", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "SRR10566619", "url": "https://sra-pub-run-odp.s3.amazonaws.com/sra/SRR10566619/SRR10566619", "size": "11304576569", "date": "2019-12-01 10:27:24", "md5": "affc7920134d1d3b979d7fa413c61b02", "version": "1", "semantic_name": "SRA Normalized", "supertype": "Primary ETL", "sratoolkit": "1"}}, {"Alternatives": [null, null, null], "@attributes": {"cluster": "public", "filename": "SRR10566619.sralite", "url": "https://sra-downloadb.be-md.ncbi.nlm.nih.gov/sos5/sra-pub-zq-16/SRR010/566/SRR10566619.sralite.1", "size": "8426537053", "date": "2020-06-22 12:58:37", "md5": "afede1093b4afb183f8874b72849ccbd", "version": "1", "semantic_name": "SRA Lite", "supertype": "Primary ETL", "sratoolkit": "1"}}]