EXPERIMENT_TITLE: HiC of hTERT-HMEC: CQ-35-L-40a_HiC_read1
STUDY_DESCRIPTOR_STUDY_ABSTRACT: To understand the functional impact of aneuploidy in phenotypically normal cells, we induced aneuploidization by inhibiting spindle assembly checkpoint in hTERT-immortalized human mammary epithelial and renal tubular epithelial cells. After single-cell isolation, clones were cultured for a long-term to study their karyotypic evolution and their impact on growth properties. A number of clones were sequenced for their genomic DNA and mRNA to understand the impact of aneuploidy in mutagenesis and transcriptional profile.
SAMPLE_TITLE: CQ_35_L_40a_HiC_read1.fastq
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "isolate", "VALUE": "not applicable"}, {"TAG": "age", "VALUE": "not applicable"}, {"TAG": "biomaterial_provider", "VALUE": "Stephen J. Elledge, Brigham and Women's Hospital, NRB160 77 Avenue Louis Pasteur, Boston, MA 02115"}, {"TAG": "collection_date", "VALUE": "2019-09-05"}, {"TAG": "geo_loc_name", "VALUE": "not applicable"}, {"TAG": "sex", "VALUE": "female"}, {"TAG": "tissue", "VALUE": "mammary epithelial cells"}, {"TAG": "cell_line", "VALUE": "hTERT-HMEC"}, {"TAG": "cell_type", "VALUE": "mammary epithelial cells"}, {"TAG": "dev_stage", "VALUE": "adult"}, {"TAG": "disease", "VALUE": "normal"}, {"TAG": "background ploidy", "VALUE": "4"}, {"TAG": "class", "VALUE": "4N-aneuploid"}, {"TAG": "Figure", "VALUE": "Fig_3g-h_and_S8"}, {"TAG": "type", "VALUE": "HiC"}, {"TAG": "id", "VALUE": "SAMEVW000896"}, {"TAG": "num", "VALUE": "896"}, {"TAG": "BioSampleModel", "VALUE": "Human"}]
Pool_Member_@attributes_sample_title: CQ_35_L_40a_HiC_read1.fastq
RUN_SET_RUN_Pool_Member_@attributes_sample_title: CQ_35_L_40a_HiC_read1.fastq
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