EXPERIMENT_TITLE: Capture Hi-C (HiCap) experiments performed on LUHMES cell line differentiated in three (D3) and six days (D6). We fragmented the genome using DpnII. HiCap experiments at each time point (D1, D3 and D6) are performed in two replicates
EXPERIMENT_DESIGN_LIBRARY_DESCRIPTOR_LIBRARY_CONSTRUCTION_PROTOC: Cell line LUHMES Capture Hi-C method, please see https://doi.org/10.1007/978-1-0716-2497-5_5 for detailed protocol Capture Hi-C method, please see https://doi.org/10.1007/978-1-0716-2497-5_5 for detailed protocol
STUDY_DESCRIPTOR_STUDY_ABSTRACT: LUHMES cells are non-tumorigenic model of human dopaminergic neurons. Their physiology and phenotypic changes upon differentiation can provide clues into the pathology of neurological diseases such as dyslexia, autism, schizophrenia.
SAMPLE_TITLE: HiCap_D1_rep1
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "ENA first public", "VALUE": "2024-01-14"}, {"TAG": "INSDC center name", "VALUE": "Royal Institute of Technology"}, {"TAG": "INSDC status", "VALUE": "public"}, {"TAG": "Submitter Id", "VALUE": "E-MTAB-13665:HiCap_D1_rep1"}, {"TAG": "broker name", "VALUE": "ArrayExpress"}, {"TAG": "cell_line", "VALUE": "LUHMES"}, {"TAG": "cell_type", "VALUE": "neuron"}, {"TAG": "collection date", "VALUE": "not collected"}, {"TAG": "common name", "VALUE": "human"}, {"TAG": "developmental stage", "VALUE": "8 weeks gestation"}, {"TAG": "geographic location (country and/or sea)", "VALUE": "not collected"}, {"TAG": "isolate", "VALUE": "not applicable"}, {"TAG": "organism part", "VALUE": "brain"}, {"TAG": "sample name", "VALUE": "E-MTAB-13665:HiCap_D1_rep1"}, {"TAG": "scientific_name", "VALUE": "Homo sapiens"}, {"TAG": "stimulus", "VALUE": "Day 1 differentiation"}]
Pool_Member_@attributes_sample_title: HiCap_D1_rep1
RUN_SET_RUN_Pool_Member_@attributes_sample_title: HiCap_D1_rep1
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