EXPERIMENT_TITLE: GSM8323376: Veh; Homo sapiens; Hi-C
EXPERIMENT_DESIGN_LIBRARY_DESCRIPTOR_LIBRARY_CONSTRUCTION_PROTOC: DNA were extracted using Arima Genomics HiC kit Hi-C-library preparation
STUDY_DESCRIPTOR_STUDY_ABSTRACT: This study investigates the role of noncoding RNAs in resistance to the anti-androgen drug daro-lutamide in prostate cancer. RNA sequencing identified LOC730101 as a significantly elevated lncRNA in darolutamide-resistant cells. Silencing LOC730101 reduced cell proliferation, indicating its role in drug resistance. Overall design: To investigate the lncRNA function in DaroR resistant cells
SAMPLE_TITLE: Veh
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "source_name", "VALUE": "Prostate cancer"}, {"TAG": "tissue", "VALUE": "Prostate cancer"}, {"TAG": "cell line", "VALUE": "LNCaP"}, {"TAG": "cell type", "VALUE": "hormone sensitive prostate cancer"}, {"TAG": "genotype", "VALUE": "WT"}, {"TAG": "treatment", "VALUE": "DMSO"}, {"TAG": "geo_loc_name", "VALUE": "missing"}, {"TAG": "collection_date", "VALUE": "missing"}]
Pool_Member_@attributes_sample_title: Veh
RUN_SET_RUN_Pool_Member_@attributes_sample_title: Veh
RUN_SET_RUN_SRAFiles_SRAFile: [{"Alternatives": null, "@attributes": {"cluster": "public", "filename": "veh_1.fq.gz", "size": "51568053342", "date": "2024-06-12 11:13:40", "md5": "5794925412526a603aee882a47fe7609", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "veh_2.fq.gz", "size": "53886447832", "date": "2024-06-12 11:15:50", "md5": "1f61667b846c7b9a685836037d10c775", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "SRR29369903", "url": "https://sra-pub-run-odp.s3.amazonaws.com/sra/SRR29369903/SRR29369903", "size": "67456218259", "date": "2024-06-12 11:31:33", "md5": "2d07f35c7b78b04fe56b2f79b93643f6", "version": "1", "semantic_name": "SRA Normalized", "supertype": "Primary ETL", "sratoolkit": "1"}}, {"Alternatives": [null, null, null], "@attributes": {"cluster": "public", "filename": "SRR29369903.lite", "url": "https://sra-downloadb.be-md.ncbi.nlm.nih.gov/sos6/sra-pub-zq-40/SRR029/29369/SRR29369903/SRR29369903.lite.1", "size": "54495317871", "date": "2024-06-12 13:06:39", "md5": "703507e3af120e399c283bceb545a697", "version": "1", "semantic_name": "SRA Lite", "supertype": "Primary ETL", "sratoolkit": "1"}}]