EXPERIMENT_TITLE: GSM4198770: BLaER subclone, 24h_CTCF_AID_DMSO_HiC_rep2; Homo sapiens; Hi-C
EXPERIMENT_DESIGN_LIBRARY_DESCRIPTOR_LIBRARY_CONSTRUCTION_PROTOC: Cells were collected by centrifugation. Crosslinked nuclei were digested with MboI followed by fill-in with bio-dATP, in-situ ligation and DNA extraction. DNA was sonicated and libraries were constructed using the the NEBNext DNA Library Prep Kit (New England Biolabs).
STUDY_DESCRIPTOR_STUDY_ABSTRACT: Studies of genome topology, chromatin state and gene expression dynamic during human B cell to macrophage transdifferentiation with and without CTCF Overall design: Genome topology profiling during  human B cell to macrophage transdifferentiation with and without CTCF using insitu HiC
SAMPLE_TITLE: BLaER subclone, 24h_CTCF_AID_DMSO_HiC_rep2
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "source_name", "VALUE": "Leukemia cell line"}, {"TAG": "subclone", "VALUE": "BLaER subclone CTCF-AID (Auxin Inducible Degron)"}, {"TAG": "treatment", "VALUE": "CEBPA+DMSO"}, {"TAG": "time", "VALUE": "168h"}]
Pool_Member_@attributes_sample_title: BLaER subclone, 24h_CTCF_AID_DMSO_HiC_rep2
RUN_SET_RUN_Pool_Member_@attributes_sample_title: BLaER subclone, 24h_CTCF_AID_DMSO_HiC_rep2
RUN_SET_RUN_SRAFiles_SRAFile: [{"Alternatives": null, "@attributes": {"cluster": "public", "filename": "1bce36e87_8b15391e7_read1.fastq.gz", "size": "15156087906", "date": "2019-12-01 09:24:21", "md5": "c9d1ec08e16cd47a750986cb6e85cad5", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "1bce36e87_8b15391e7_read2.fastq.gz", "size": "15699463827", "date": "2019-12-01 09:25:39", "md5": "964ef42103f43e086009decb67e96cf8", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "SRR10566632", "url": "https://sra-pub-run-odp.s3.amazonaws.com/sra/SRR10566632/SRR10566632", "size": "19951126448", "date": "2019-12-01 09:31:32", "md5": "ba4708f01839f5527dcff999921800a7", "version": "1", "semantic_name": "SRA Normalized", "supertype": "Primary ETL", "sratoolkit": "1"}}, {"Alternatives": [null, null, null], "@attributes": {"cluster": "public", "filename": "SRR10566632.sralite", "url": "https://sra-downloadb.be-md.ncbi.nlm.nih.gov/sos3/sra-pub-zq-22/SRR010/566/SRR10566632.sralite.1", "size": "9813199089", "date": "2020-06-24 02:23:01", "md5": "b6657ecb8cf744a38e466687e41eee04", "version": "1", "semantic_name": "SRA Lite", "supertype": "Primary ETL", "sratoolkit": "1"}}]