EXPERIMENT_TITLE: GSM4198759: BLaER cell line, 48h_HiC_rep2; Homo sapiens; Hi-C
EXPERIMENT_DESIGN_LIBRARY_DESCRIPTOR_LIBRARY_CONSTRUCTION_PROTOC: Cells were collected by centrifugation. Crosslinked nuclei were digested with MboI followed by fill-in with bio-dATP, in-situ ligation and DNA extraction. DNA was sonicated and libraries were constructed using the the NEBNext DNA Library Prep Kit (New England Biolabs).
STUDY_DESCRIPTOR_STUDY_ABSTRACT: Studies of genome topology, chromatin state and gene expression dynamic during human B cell to macrophage transdifferentiation with and without CTCF Overall design: Genome topology profiling during  human B cell to macrophage transdifferentiation with and without CTCF using insitu HiC
SAMPLE_TITLE: BLaER cell line, 48h_HiC_rep2
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "source_name", "VALUE": "Leukemia cell line"}, {"TAG": "cell line", "VALUE": "BLaER"}, {"TAG": "treatment", "VALUE": "CEBPA"}, {"TAG": "time", "VALUE": "48h"}]
Pool_Member_@attributes_sample_title: BLaER cell line, 48h_HiC_rep2
RUN_SET_RUN_Pool_Member_@attributes_sample_title: BLaER cell line, 48h_HiC_rep2
RUN_SET_RUN_SRAFiles_SRAFile: [{"Alternatives": null, "@attributes": {"cluster": "public", "filename": "141ef71ac_28b772509_read1.fastq.gz", "size": "11058225941", "date": "2019-12-01 10:41:35", "md5": "f879f4a7cccfcd1796ab844065e23602", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "141ef71ac_28b772509_read2.fastq.gz", "size": "11485367710", "date": "2019-12-01 10:36:04", "md5": "2a9f9975a853ab8ab32ce5a712afe77f", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "SRR10566621", "url": "https://sra-pub-run-odp.s3.amazonaws.com/sra/SRR10566621/SRR10566621", "size": "15281507449", "date": "2019-12-01 10:48:26", "md5": "6d60fc0e8a90e01876af888c8666f6e9", "version": "1", "semantic_name": "SRA Normalized", "supertype": "Primary ETL", "sratoolkit": "1"}}, {"Alternatives": [null, null, null], "@attributes": {"cluster": "public", "filename": "SRR10566621.sralite", "url": "https://sra-downloadb.be-md.ncbi.nlm.nih.gov/sos5/sra-pub-zq-16/SRR010/566/SRR10566621.sralite.1", "size": "10294114029", "date": "2020-06-20 21:22:18", "md5": "28a61dcb3c83a5c6e5f22551bae1aafa", "version": "1", "semantic_name": "SRA Lite", "supertype": "Primary ETL", "sratoolkit": "1"}}]