EXPERIMENT_TITLE: GSM4198765: BLaER subclone, B_CTCF_AID_HiC; Homo sapiens; Hi-C
EXPERIMENT_DESIGN_LIBRARY_DESCRIPTOR_LIBRARY_CONSTRUCTION_PROTOC: Cells were collected by centrifugation. Crosslinked nuclei were digested with MboI followed by fill-in with bio-dATP, in-situ ligation and DNA extraction. DNA was sonicated and libraries were constructed using the the NEBNext DNA Library Prep Kit (New England Biolabs).
STUDY_DESCRIPTOR_STUDY_ABSTRACT: Studies of genome topology, chromatin state and gene expression dynamic during human B cell to macrophage transdifferentiation with and without CTCF Overall design: Genome topology profiling during  human B cell to macrophage transdifferentiation with and without CTCF using insitu HiC
SAMPLE_TITLE: BLaER subclone, B_CTCF_AID_HiC
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "source_name", "VALUE": "Leukemia cell line"}, {"TAG": "subclone", "VALUE": "BLaER subclone CTCF-AID (Auxin Inducible Degron)"}, {"TAG": "treatment", "VALUE": "Non-treated"}, {"TAG": "time", "VALUE": "0h"}]
Pool_Member_@attributes_sample_title: BLaER subclone, B_CTCF_AID_HiC
RUN_SET_RUN_Pool_Member_@attributes_sample_title: BLaER subclone, B_CTCF_AID_HiC
RUN_SET_RUN_SRAFiles_SRAFile: [{"Alternatives": null, "@attributes": {"cluster": "public", "filename": "b029df3ec_d1119898d_read1.fastq.gz", "size": "15219904926", "date": "2019-12-01 09:42:37", "md5": "82554d71151899bf4291a9a1ff339bc7", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "b029df3ec_d1119898d_read2.fastq.gz", "size": "15392546306", "date": "2019-12-01 09:35:59", "md5": "03bb18a418dd537f07afcb24606a0b54", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "SRR10566627", "url": "https://sra-pub-run-odp.s3.amazonaws.com/sra/SRR10566627/SRR10566627", "size": "19712563857", "date": "2019-12-01 10:03:30", "md5": "d1a94db40b7f30026f5f36c978d7d655", "version": "1", "semantic_name": "SRA Normalized", "supertype": "Primary ETL", "sratoolkit": "1"}}, {"Alternatives": [null, null, null], "@attributes": {"cluster": "public", "filename": "SRR10566627.sralite", "url": "https://sra-downloadb.be-md.ncbi.nlm.nih.gov/sos3/sra-pub-zq-22/SRR010/566/SRR10566627.sralite.1", "size": "9847263924", "date": "2020-06-21 14:40:54", "md5": "f0e0ed6f3528e47548f3cdf7bf4be844", "version": "1", "semantic_name": "SRA Lite", "supertype": "Primary ETL", "sratoolkit": "1"}}]