EXPERIMENT_TITLE: GSM4198753: BLaER cell line, 144h_HiC_rep1; Homo sapiens; Hi-C
EXPERIMENT_DESIGN_LIBRARY_DESCRIPTOR_LIBRARY_CONSTRUCTION_PROTOC: Cells were collected by centrifugation. Crosslinked nuclei were digested with MboI followed by fill-in with bio-dATP, in-situ ligation and DNA extraction. DNA was sonicated and libraries were constructed using the the NEBNext DNA Library Prep Kit (New England Biolabs).
STUDY_DESCRIPTOR_STUDY_ABSTRACT: Studies of genome topology, chromatin state and gene expression dynamic during human B cell to macrophage transdifferentiation with and without CTCF Overall design: Genome topology profiling during  human B cell to macrophage transdifferentiation with and without CTCF using insitu HiC
SAMPLE_TITLE: BLaER cell line, 144h_HiC_rep1
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "source_name", "VALUE": "Leukemia cell line"}, {"TAG": "cell line", "VALUE": "BLaER"}, {"TAG": "treatment", "VALUE": "CEBPA"}, {"TAG": "time", "VALUE": "144h"}]
Pool_Member_@attributes_sample_title: BLaER cell line, 144h_HiC_rep1
RUN_SET_RUN_Pool_Member_@attributes_sample_title: BLaER cell line, 144h_HiC_rep1
RUN_SET_RUN_SRAFiles_SRAFile: [{"Alternatives": null, "@attributes": {"cluster": "public", "filename": "1c0ccd992_eb5e1b9ac_read1.fastq.gz", "size": "17319460583", "date": "2019-12-01 09:45:49", "md5": "caf09e707e55b647d5c3d5d412deb6a4", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "1c0ccd992_eb5e1b9ac_read2.fastq.gz", "size": "18038990019", "date": "2019-12-01 09:38:25", "md5": "e07e1978501d00be08daa19c35c49cbb", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "SRR10566615", "url": "https://sra-pub-run-odp.s3.amazonaws.com/sra/SRR10566615/SRR10566615", "size": "22453013607", "date": "2019-12-01 09:56:11", "md5": "08aba6c43547dca4ed1adb824914250b", "version": "1", "semantic_name": "SRA Normalized", "supertype": "Primary ETL", "sratoolkit": "1"}}, {"Alternatives": [null, null, null], "@attributes": {"cluster": "public", "filename": "SRR10566615.sralite", "url": "https://sra-downloadb.be-md.ncbi.nlm.nih.gov/sos5/sra-pub-zq-16/SRR010/566/SRR10566615.sralite.1", "size": "12144977407", "date": "2020-06-21 14:49:56", "md5": "3eab62fa35161c019339483768caa926", "version": "1", "semantic_name": "SRA Lite", "supertype": "Primary ETL", "sratoolkit": "1"}}]