EXPERIMENT_TITLE: GSM4198755: BLaER cell line, B_HiC_rep2; Homo sapiens; Hi-C
EXPERIMENT_DESIGN_LIBRARY_DESCRIPTOR_LIBRARY_CONSTRUCTION_PROTOC: Cells were collected by centrifugation. Crosslinked nuclei were digested with MboI followed by fill-in with bio-dATP, in-situ ligation and DNA extraction. DNA was sonicated and libraries were constructed using the the NEBNext DNA Library Prep Kit (New England Biolabs).
STUDY_DESCRIPTOR_STUDY_ABSTRACT: Studies of genome topology, chromatin state and gene expression dynamic during human B cell to macrophage transdifferentiation with and without CTCF Overall design: Genome topology profiling during  human B cell to macrophage transdifferentiation with and without CTCF using insitu HiC
SAMPLE_TITLE: BLaER cell line, B_HiC_rep2
SAMPLE_SAMPLE_ATTRIBUTES_SAMPLE_ATTRIBUTE: [{"TAG": "source_name", "VALUE": "Leukemia cell line"}, {"TAG": "cell line", "VALUE": "BLaER"}, {"TAG": "treatment", "VALUE": "Non-treated"}, {"TAG": "time", "VALUE": "0h"}]
Pool_Member_@attributes_sample_title: BLaER cell line, B_HiC_rep2
RUN_SET_RUN_Pool_Member_@attributes_sample_title: BLaER cell line, B_HiC_rep2
RUN_SET_RUN_SRAFiles_SRAFile: [{"Alternatives": null, "@attributes": {"cluster": "public", "filename": "b029df3ec_28b772509_read2.fastq.gz", "size": "13440471669", "date": "2019-12-01 10:50:42", "md5": "0cc47c08589a41c0f75a0b0c5b593960", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "SRR10566617", "url": "https://sra-pub-run-odp.s3.amazonaws.com/sra/SRR10566617/SRR10566617", "size": "18118437758", "date": "2019-12-01 11:08:21", "md5": "db5666a4d79fa2300c6197706337320b", "version": "1", "semantic_name": "SRA Normalized", "supertype": "Primary ETL", "sratoolkit": "1"}}, {"Alternatives": [null, null, null], "@attributes": {"cluster": "public", "filename": "SRR10566617.sralite", "url": "https://sra-downloadb.be-md.ncbi.nlm.nih.gov/sos5/sra-pub-zq-16/SRR010/566/SRR10566617.sralite.1", "size": "11953230070", "date": "2020-06-22 13:03:34", "md5": "a3d384898440a7907ffd9987b31a1a10", "version": "1", "semantic_name": "SRA Lite", "supertype": "Primary ETL", "sratoolkit": "1"}}, {"Alternatives": null, "@attributes": {"cluster": "public", "filename": "b029df3ec_28b772509_read1.fastq.gz", "size": "12999436054", "date": "2019-12-01 10:56:06", "md5": "0b608640b377b16de893113c4b8181e3", "version": "1", "semantic_name": "fastq", "supertype": "Original", "sratoolkit": "0"}}]