OpportunityTitle: Model Systems for Fragile X Pre-Mutation and Primary Ovarian Insufficiency (FX-POI) (R21)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Foreign (non-U.S.) components of U.S. Organizations are allowed.
Description: The purpose of this funding opportunity announcement (FOA) is to stimulate the development of new model systems and/or the thorough characterization of the ovarian phenotype of existing models of fragile X associated premature ovarian insufficiency (FX-POI). New and well-characterized models of FX-POI will help us to answer fundamental questions about the role of the FMR1 repeat expansion in ovarian function and reproductive aging, and allow the field to advance into evidence based clinical research on fragile X pre-mutation carriers who are at risk for POI.
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GrantorContactText: NIH OER Webmaster&lt;br/&gt;FBOWebmaster@OD.NIH.GOV&lt;br/&gt;