OpportunityTitle: The Development of Frontal Cortex and Limbic System and their roles in Drug Abuse or Mental Health (R21)
AdditionalInformationOnEligibility: Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith-based or community-based organizations can apply. Any individual with the skills, knowledge, and resources necessary to carry out the proposed research as the Project Director/Principal Investigator (PD/PI) is invited to work with his/her organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support.     Applicants may submit more than one application, provided each application is scientifically distinct.
Description: -This funding opportunity announcement (FOA) solicits exploratory/developmental (R21) grant applications to study the development of the frontal and prefrontal cortices, together with the subcortical areas of the limbic system, that play significant roles in mediating emotional and motivated behavior. This initiative is designed to support basic neuroscience research into the fundamental mechanisms of development of the frontal and prefrontal cortices, as well as the midbrain and basal forebrain structures that mediate a number of functions related to drug abuse and psychiatric disorders including: the euphoric properties of drugs, actions of psychotherapeutic agents, and cognitive and emotional function. A major goal of this initiative is to understand how exposure to drugs of abuse affects the cellular and molecular mechanisms underlying nervous system development of circuits involved in drug abuse and addiction. An additional goal is to understand how alterations in the normal developmental trajectory might underlie the pathophysiology of psychiatric disorders with putative developmental etiologies. -This funding opportunity will utilize the NIH exploratory/developmental (R21) grant mechanism and runs in parallel with a FOA of identical scientific scope (PA-06-444) that utilizes the NIH investigator-initiated research project (R01) award mechanism. -Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the mechanism numbers, quality, duration, and costs of the applications received.
GrantorContactEmailDescription: If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster
GrantorContactText: NIH OER Webmaster &lt;br/&gt;FBOWebmaster@OD.NIH.GOV &lt;br/&gt;
CloseDateExplanation: Multiple Receipt Dates - See Link to Full Announcement for details.