OpportunityTitle: Limited Competition: Renewal of the Caenorhabditis Intervention Testing Program (U01)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Description: The purpose of the Caenorhabditis Interventions Testing Program (CITP) is to test, under standardized conditions at a consortium of three sites, potential intervention strategies which may decelerate the rate of aging in genetically diverse species and strains of Caenorhabditis. All three laboratories in the CITP use identical standard operating procedures to test the same compounds (interventions) at the same concentrations and under the same conditions. The CITP will continue to use life span as its primary outcome for an intervention on a currently defined set of Caenorhabditis species and strains. This FOA calls for renewal and expansion of the scientific scope of the CITP with the following goals: 1. Continue to test compounds for effects on lifespan; 2. Increase the number of strains examined in lifespan studies as described in RFA AG-13-010. 3. Incorporate a limited set of studies for health span on selected compounds; 4. Incorporate studies to establish optimal effective doses when an initial test indicates the compound may be robust for its effect on lifespan across numerous strains of Caenorhabditis.
GrantorContactEmailDescription: If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster
GrantorContactText: NIH OER Webmaster&lt;br/&gt;FBOWebmaster@OD.NIH.GOV&lt;br/&gt;