OpportunityTitle: Harvesting the Neuroimaging Cornucopia for Pancreatic Islet Imaging Reagents for Diabetes Research (DP3)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.  Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Description: This Funding Opportunity Announcement (FOA) encourage DP3 applications from institutions/organizations to allow researchers with access to major clinical nuclear molecular imaging facilities to screen their libraries of existing positron emission tomography (PET) or single photon emission computed tomography (SPECT) neuroimaging agents that are already approved for use in human subjects research in order to find tools to enhance in vivo study of the beta cells of the human pancreatic islet. Diabetes ensues with the loss or dysfunction of beta cells and the inability to monitor their mass is an enormous barrier to understanding the natural history of human diabetes or the course of disease in an individual patient. Because human pancreatic islet beta cells are distinct from those of rodent models of diabetes and yet have many of the neurotransmitter systems found in the human brain, screening of existing human neuroimaging agents directly in human subjects and human tissues may be a cost-efficient way to identify promising beta cell imaging agents.
GrantorContactEmailDescription: If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster
GrantorContactText: NIH OER Webmaster&lt;br/&gt;FBOWebmaster@OD.NIH.GOV&lt;br/&gt;