OpportunityTitle: Mechanistic Research on CAM Natural Products (R01)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following:   Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Description: Purpose. This FOA issued by the National Center for Complementary and Alternative Medicine (NCCAM) in collaboration with the Office of Dietary Supplements (ODS), at the National Institutes of Health, invites Research Project Grant (R01) applications to study the potential mechanisms of action of promising CAM natural products (NPs). Natural products are widely used by Americans for health purposes. Knowledge about the active components, their molecular and cellular targets, as well as markers of potential beneficial or harmful biological effects are critical pieces of preliminary information needed to insure maximally informative clinical efficacy studies on these products. Research on the development of improved methodology for the isolation and characterization of constituents of natural products and on their determination in the natural matrix will also be supported under this initiative. Mechanism of Support. This FOA will utilize the R01 award mechanism. Funds Available and Anticipated Number of Awards. NIH participants are contributing $8.1 million in total to this FOA. The total amount to be awarded in the first year is approximately $1.625 million (total costs). Approximately 2-4 awards are anticipated. The total amount to be awarded in the second and third year is approximately $3.25 million (total costs). Approximately 5-7 awards are anticipated per year. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications.
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GrantorContactText: NIH OER Webmaster &lt;br/&gt;FBOWebmaster@OD.NIH.GOV &lt;br/&gt;