OpportunityTitle: Long-term Effectiveness of COVID-19 Vaccines Against Symptomatic and Asymptomatic Infection in the General Population and in Populations at Increased Risk for COVID-19
AdditionalInformationOnEligibility: &amp;#8226;   The following types of Higher Education Institutions are always encouraged to apply for CDC support as Non-profit Public or Private Institutions of Higher Education:              Hispanic-serving Institutions     Historically Black Colleges and Universities (HBCUs)     Tribally Controlled Colleges and Universities (TCCUs)     Alaska Native and Native Hawaiian Serving Institutions        &amp;#8226;   Nonprofits (Other than Institutions of Higher Education)    &amp;#8226;   Eligible Agencies of the Federal Government    &amp;#8226;   Faith-based or Community-based Organizations    &amp;#8226;   U.S. Territory or Possession    &amp;#8226;   Regional Organizations    &amp;#8226;   Bona Fide Agents: A Bona Fide Agent is an agency/organization identified by the state as eligible to submit an application under the state eligibility in lieu of a state application. If applying as a bona fide agent of a state or local government, a legal, binding agreement from the state or local government as documentation of the status is required. Attach with &amp;#34;Other Attachment Forms&amp;#34; when submitting via https://www.grants.gov    &amp;#8226;   Federally Funded Research and Development Centers (FFRDCs): FFRDCs are operated, managed, and/or administered by a university or consortium of universities, other not-for-profit or nonprofit organization, or an industrial firm, as an autonomous organization or as an identifiable separate operating unit of a parent organization. A FFRDC meets some special long-term research or development need which cannot be met as effectively by an agency&amp;#8217;s existing in-house or contractor resources. FFRDC&amp;#8217;s enable agencies to use private sector resources to accomplish tasks that are integral to the mission and operation of the sponsoring agency. For more information on FFRDCs, go to https://gov.ecfr.io/cgi-bin/searchECFR              For this announcement, applicants may include collaborators or consultants from foreign institutions.
Description: The purpose of this notice of funding opportunity (NOFO) is to support research to evaluate the long-term effectiveness of COVID-19 vaccines against symptomatic and asymptomatic infections through long-term follow-up of vaccinated individuals (adults and children) and to assess immune response metrics, symptoms, and the development of asymptomatic infection/viral shedding. Studies should be adequately powered to generate product- and variant-specific vaccine effectiveness estimates and to assess risk factors for vaccine breakthrough, including demographic, immunologic, and virologic risk factors, where possible.
GrantorContactEmailDescription: hft6@cdc.gov