OpportunityTitle: Collaborative Networks to Advance Delirium Research (R24)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Description: Delirium, defined as an acute impairment of cognition and attention, is a common complication of severe illness and surgery in older adults. It is associated with multiple adverse outcomes including increased morbidity, mortality, functional and cognitive decline, and institutionalization. Delirium remains markedly underdiagnosed.Moreover, the underlying mechanisms, and thereby potential treatment or prevention targets, are inadequately understood, as is prognosis. Addressing important research gaps may improve approaches for appropriate prevention and management, especially as studies of multicomponent interventions suggest that delirium may be at least 30-40% preventable.This FOA is intended to support a collaborative network to advance scientific research on the causes, mechanisms, outcomes, diagnosis, prevention, and treatment of delirium in older adults.
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