OpportunityTitle: Targeting Co-dependent Molecular Pathways in Oral Cancer (U01)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are  eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are  eligible to apply.  Foreign components, as defined in the NIH Grants Policy Statement, are  allowed.
Description: The purpose of this Funding Opportunity Announcement (FOA) is to support multi-disciplinary projects aimed at the development of new targeted and effective therapies through systematic use and leveraging of recently identified genomic abnormalities and attendant changes in gene and/or protein expression profiles in human oral cancer samples. The goal of the FOA is the identification of co-dependent survival and proliferation pathways in oral cancer cells and the elucidation of potential signaling pathways that can be targeted with combination therapy approaches. This initiative requires collaboration of multi-disciplinary research teams that include cancer biologists, computational biologists, model system specialists and/or screening assay specialists. The emphasis will be on the conceptual phase of target identification and exploration including proof-of-concept phase.
GrantorContactEmailDescription: If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster
GrantorContactText: NIH OER Webmaster&lt;br/&gt;FBOWebmaster@OD.NIH.GOV&lt;br/&gt;