OpportunityTitle: Studies of Cytosolic DNAs in the Interactions of Aging Hallmarks (R01 Clinical Trial Not Allowed)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Description: This Funding Opportunity Announcement (FOA) invites applications on novel studies of the cytosolic DNA sensing mechanisms in the interactions of the aging hallmarks. The goal of this FOA is to support applications that will lead to an in-depth understanding of the molecular mechanisms that determine the effects of cytosolic DNAs on aging hallmarks in the context of aging and longevity. Research supported by this FOA should lead to new insights to address some critical mechanistic questions relevant to the role of aging hallmarks in aging and aging-related diseases. This FOA encourages innovative, mechanistic approaches to identify and characterize interactions of aging hallmarks mediated by cytosolic DNAs that ultimately modulate the regulation of healthspan and/or longevity.
GrantorContactEmailDescription: See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
GrantorContactText: NIH OER Webmaster&lt;br/&gt;OERWebmaster03@od.nih.gov