OpportunityTitle: Limited Competition - Multicenter AIDS Cohort Study: Center for the Coordination, Analysis, and Management of the MACS (CAMACS)(UM1)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following: 1. Eligible Applicants   Eligible Organizations Only one application from the current CAMACS awardee may be submitted in response to this limited competition:    Johns Hopkins University (Baltimore, MD) &#191; Center for the Coordination, Analysis, and Management of MACS (CAMACS)     Foreign Institutions Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.  Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.  Required Registrations Applicant organizations must complete the following registrations as described in the PHS 398 Application Guide to be eligible to apply for or receive an award. Applicants must have a valid Dun and Bradstreet Universal Numbering System (DUNS) number in order to begin each of the following registrations.  System for Award Management (SAM)&#191; must maintain an active entity registration (formerly CCR registration), to be renewed at least annually. Use the Sam.gov &#191;Manage Entity&#191; function to manage your entity registrations.  See the Grants Registration User Guide at SAM.gov for additional information.  eRA Commons  All Program Directors/Principal Investigators (PD(s)/PI(s)) must also work with their institutional officials to register with the eRA Commons or ensure their existing eRA Commons account is affiliated with the eRA Commons account of the applicant organization.   All registrations must be completed by the application due date. Applicant organizations are strongly encouraged to start the registration process at least 6 weeks prior to the application due date.  Eligible Individuals (Program Director/Principal Investigator) Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) is invited to work with his/her organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support.  For institutions/organizations proposing multiple PDs/PIs, visit the Multiple Program Director/Principal Investigator Policy and submission details in the Senior/Key Person Profile (Expanded) Component of the PHS 398 Application Guide.
Description: The purpose of this FOA is to renew the Center for the Coordination, Analysis, and Management of the Multicenter AIDS Cohort Study (CAMACS), and continue support for clinical, epidemiologic and basic research on a cohort of men who report sex with men (MSM). The MACS will continue to characterize the long-term, natural and treated history of HIV infection in MSM, provide insight into the clinical epidemiology of HIV, and further our understanding of predictors of disease among HIV positive MSM. The MACS will also transition to a rolling cohort design to replace existing cohort members who die or otherwise are permanently lost to follow-up. Due to the demonstrated capacity to recruit and retain this unique population, the depth of data and specimens collected over decades, and the need for continued follow-up, this competition will be limited to the current awardee institution for the CAMACS.
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