OpportunityTitle: Limited Competition: Clinical Research Sites (CRS) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trial Not Allowed)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following: See NOFO for further eligibility criteria.  Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.  Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.  Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Description: The purpose of this Notice of Funding Opportunity (NOFO) is to renew the MACS/WIHS Combined Cohort Study of HIV in United States Adults (MWCCS) for a 6-year project period (2026-2032). Continuation of this epidemiological cohort study of middle-aged and older people living with HIV (PLWH), along with comparable people living without HIV (PLWOH) will enable the continued follow-up of a deeply phenotyped cohort of more than 5,600 participants from across the United States. This initiative will utilize a populomics approach, i.e., examination of health determinants across multiple scales of influence (e.g. molecular, cellular, physiological, lifestyle/behavioral, household, neighborhood, environmental, cultural, and sociopolitical) using multi-disciplinary methods to investigate the web of influences impacting the health, quality of life, and survival of adults living with HIV. This NOFO is limited to institutions who were funded under RFA-HL-19-008 and will fund up to 13 Clinical Research Sites (CRS) for the MWCCS. This NOFO runs in parallel with two companion U01 NOFOs: RFA-HL-26-010 (Limited Competition: Data Analysis and Sharing Center (DASC) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trials Not Allowed)) and RFA-HL-26-011 (Leadership and Coordination Center (LACC) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trials Not Allowed)).
GrantorContactEmailDescription: See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
GrantorContactText: NIH Grants Information&lt;br/&gt;grantsinfo@nih.gov