OpportunityTitle: Prematurity-Related Ventilatory Control (Pre-Vent):  Role in Respiratory Outcomes Clinical Research Centers (CRC) (U01)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Description: NHLBI invites applications from institutions willing to participate as a Clinical Research Center (CRC) for the Prematurity-Related Ventilatory Control (Pre-Vent) observational program under a cooperative agreement.The objective of the program is to investigate mechanisms of ventilatory control (e.g. chemoreceptor, mechanoreceptor, developmental, etc.) that contribute to instability of oxygenation and risk of morbidity and mortality in premature infants during and after the Neonatal Intensive Care Unit (NICU) using a prospective observational cohort. The ultimate goal is to gain greater insight into the pathogenesis of chronic respiratory disease of the premature, and discover targets for new prevention and treatment strategies to improve outcomes for very vulnerable children at the beginning of life.
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