OpportunityTitle: Harnessing Inflammation for Reconstruction of Oral and Craniofacial Tissues (R21)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following:   Alaska Native and Native Hawaiian Serving Institutions; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Description: # Purpose. This FOA issued by the National Institute of Dental and Craniofacial Research solicits exploratory/developmental Research Grant (R21) applications from institutions/organizations that will elucidate the molecular mechanisms of resolution of acute and chronic inflammation, and will initiate development of novel multidisciplinary approaches for predictable control and patterning of tissue inflammatory microenvironments. This FOA will support early stages of high risk-high impact research that will lead to breaking new ground or extend previous discoveries toward significant advances in our understanding of the mechanisms of inflammation resolution and tissue regeneration, and will lead to development of clinically-relevant approaches for promoting inflammation resolution, for overcoming tissue fibrosis and scarring, and for regenerating and reconstructing diseased and injured oral and craniofacial tissues. Toward these goals, this FOA encourages exploratory and developmental research that utilizes interdisciplinary and multidisciplinary approaches that integrate advances in disciplines such as, cell and developmental biology, stem cell biology, and immunology, with advances in chemistry, pharmacology, and bioengineering. Use of the multiple PI application format is strongly encouraged for this FOA. Long-term projects, or projects designed to increase knowledge in the ongoing area of investigation will not be considered under this FOA.
GrantorContactEmailDescription: OER Webmaster
GrantorContactText: GrantsInfo &lt;br/&gt;Telephone: (301) 435-0714 &lt;br/&gt;Email:  GrantsInfo@nih.gov &lt;br/&gt;Telecommunication for hearing impaired:  &lt;br/&gt; TTY 301-451-0088