OpportunityTitle: Closed Loop Technologies: Pilot and Exploratory Clinical and Behavioral Approaches to Improve Type 1 Diabetes Outcomes (R21)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Description: -Purpose . The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) of the National Institutes of Health solicit Research Project Grant (R01) applications for human studies to develop a highly reliable, easy to operate system linking continuous glucose monitoring to insulin delivery in a closed loop system.The goal is to address barriers that limit progress toward a closed loop system and specifically to 1) address behavioral factors that limit use of these systems and 2) use the technologies as tools to advance understanding of the pathophysiology of glucose regulation in patients with type 1 diabetes. Research goals include improved metabolic control with decreased glycemic excursions, increased lifestyle flexibility and improved quality of life in patients with diabetes. Only human studies will be considered responsive to this FOA. -Mechanism of Support. This FOA will utilize the R21 grant mechanism and runs in parallel with FOA, RFA-DK-08-012, that solicits applications under the R01 mechanism.
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GrantorContactText: NIH OER Webmaster&lt;br/&gt;FBOWebmaster@OD.NIH.GOV&lt;br/&gt;