OpportunityTitle: Short-term Measurements of Physical Resilience as a Predictor of Healthspan in Mice (R01)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Description: This Funding Opportunity Announcement (FOA) invites applications to develop short-term tests that provide a comprehensive measure of resilience in animal models used in aging studies. Resilience is defined here as the ability of an organism to respond to physical challenges or stresses and return to homeostasis. Increased resilience is believed to correlate with longevity and a longer health-span, but appropriate methodology to test this comprehensibly in animal models is currently lacking. The purpose of this FOA is to develop appropriate tests to measure resilience to physical, molecular and cellular stresses, as a prelude to being able to predict, using a panel of standardized short-term tests in young or middle-aged animals, whether interventions might lead to improved future health outcomes and longevity.
GrantorContactEmailDescription: If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster
GrantorContactText: NIH OER Webmaster&lt;br/&gt;FBOWebmaster@OD.NIH.GOV&lt;br/&gt;