OpportunityTitle: Phased Innovation Awards in AIDS Vaccine Research (R21/R33)
AdditionalInformationOnEligibility: Foreign institutions are not eligible to apply. Eligible agencies of the Federal Government can apply. Faith-based or community-based organizations can apply. Applicants may submit more than one application, provided each application is scientifically distinct.    Clinical trials or  first-time-in human  studies will not be supported under this FOA. (See . http://grants.nih.gov/grants/guide/notice-files/NOT-AI-05-021.html). Clinical research, including research that uses clinical specimens, is within the scope of this announcement.
Description: -Purpose. This program will support prophylactic vaccine research projects that are innovative, novel, may be high risk/high impact, and that exhibit the potential to advance AIDS prophylactic vaccine design or evaluation. All areas of investigation contributing to the development of an efficacious HIV/AIDS vaccine are welcome. Clinical trials will not be supported under this initiative. -Mechanism of Support. This FOA will utilize the NIH Phased Innovation (combined R21 [Phase I, Exploratory]/R33 [Phase II, Developmental]) grant mechanism. Awards will support milestone-driven exploratory/feasibility proof of concept studies (2 year R21 phase), with possible rapid transition to expanded development (2-3 year R33 phase). Initially funded R21 studies will be tested over two years via milestone completion, and eligible R21s will be further assessed for the R33 award. -Funds Available. Funding will be based on scientific and technical merit, program priorities, and availability of funds. The R21 award will be limited to $275,000 directs over the two year award period, and the R33 award will be limited to $300,000 in direct costs per annum. NIH anticipates that a maximum of fifty percent (50%) of the funded R21 phase awards will progress to the R33 award.
GrantorContactEmailDescription: If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster
GrantorContactText: NIH OER Webmaster&lt;br/&gt;FBOWebmaster@OD.NIH.GOV&lt;br/&gt;
CloseDateExplanation: Multiple Receipt Dates - See Link to Full Announcement for details.