OpportunityTitle: Intestinal Stem Cell Consortium (U01)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Description: Purpose. This FOA invites new applications to participate in the Intestinal Stem Cell Consortium (ISCC).The goals of this initiative are 1) to establish a network of synergistic research teams and a Coordinating Center focused on research on stem cells of the small intestine in order to 2) isolate, culture, characterize, functionally validate, and compare stem cell populations from the small intestine epithelium in vivo and in vitro, and 3) share data, biomaterials, models, reagents, resources and methods between projects in the ISCC and 4) make these publicly available through a web site to be developed by the Coordinating Center.The objective of support for this consortium is to accelerate research on stem cells of the intestinal epithelium in order to facilitate understanding of the biology and function of the intestine and aid development of therapies for intestinal diseases and conditions where damage and replacement of this epithelium are important components. Mechanism of Support. This FOA will utilize the U01 cooperative agreement grant mechanism. Funds Available and Anticipated Number of Awards. The total amount of funding that is expected to be awarded through this announcement is $3.0 Million total costs for the first year to support 5-7research projects and one Coordinating Center.
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