OpportunityTitle: Development of a model selection method for population pharmacokinetics analysis by deep-learning based reinforcement learning (U01) Clinical Trials Not Allowed
AdditionalInformationOnEligibility: Eligible Organizations  Higher Education Institutions    &#8226;   Public/State Controlled Institutions of Higher Education     &#8226;   Private Institutions of Higher Education     The following types of Higher Education Institutions are always encouraged to apply for FDA support as Public or Private Institutions of Higher Education:     o    Hispanic-serving Institutions    o    Historically Black Colleges and Universities (HBCUs)    o    Tribally Controlled Colleges and Universities (TCCUs)     o    Alaska Native and Native Hawaiian Serving Institutions    o    Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)    Nonprofits Other Than Institutions of Higher Education    &#8226;   Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)     &#8226;   Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)     For-Profit Organizations    &#8226;   Small Businesses    &#8226;   For-Profit Organizations (Other than Small Businesses)    Governments    &#8226;   State Governments     &#8226;   County Governments    &#8226;   City or Township Governments    &#8226;   Special District Governments    &#8226;   Indian/Native American Tribal Governments (Federally Recognized)     &#8226;   Indian/Native American Tribal Governments (Other than Federally Recognized)    &#8226;   U.S. Territory or Possession    Other    &#8226;   Independent School Districts    &#8226;   Public Housing Authorities/Indian Housing Authorities    &#8226;   Native American Tribal Organizations (other than Federally recognized tribal governments)    &#8226;   Faith-based or Community-based Organizations    &#8226;   Regional Organizations    &#8226;   Non-domestic (non-U.S.) Entities (Foreign Institutions)
Description: The purpose of this project is to develop a model selection method for the population pharmacokinetics (popPK) analysis using a deep-learning based reinforcement learning (RL) algorithm. The development of the method encompasses method validation and performance verification by simulations as well as real pharmacokinetics (PK) data sets.
GrantorContactEmailDescription: shashi.malhotra@fda.hhs.gov
GrantorContactText: Shashi Malhotra &lt;br/&gt;Grants Management Specialist &lt;br/&gt;Phone 2404027592