OpportunityTitle: Limited Competition for the Pediatric HIV/AIDS Cohort Study (U01)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following: This is a limited solicitation made available to the grantees funded under the first PHACS FOA (RFA-HD-05-018) as a recompetition for an additional award of up to five years. Any individual with the skills, knowledge, and resources necessary to carry out the proposed research as the PD/PI is invited to work with his/her institution to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support.
Description: Purpose. This Funding Opportunity Announcement (FOA), issued by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and the NIDA, NIAID, NIMH, NINDS, NIDCD, NHLBI, and NIAAA solicits competing renewal applications to provide support for the Pediatric HIV/AIDS Cohort Study (PHACS) to continue the observational cohorts developed during the first competitive funding cycle. These cohorts address two critical issues in HIV research:the long-term safety of in utero exposure to multiple antiretroviral drugs in HIV-exposed but uninfected children, and the interactive effects of HIV and its treatments on perinatally infected children and adolescents. Mechanism of Support. This FOA will utilize the NIH Cooperative Research Project Grant (U01) grant mechanism. Funds Available and Anticipated Number of Awards. The NICHD intends to commit approximately $5,400,000, NIDA intends to commit approximately $3,400,000, NIAID intends to commit approximately $2,000,000, NIMH intends to commit approximately $1,200,000, NINDS intends to commit approximately $750,000, NIDCD intends to commit approximately $650,000, NHLBI intends to commit approximately $600,000, and NIAAA intends to commit approximately $250,000 in total costs [Direct plus Facilities and Administrative (F &amp; A) costs] in FY 2010 to support 2 competing grants in response to this FOA, one as the PHACS Coordinating Center (CC) and the other as the PHACS Data and Operations Center (DOC). Budget and Project Period.An applicant for the PHACS CC may request a project period of up to 5 years and an expected first-year budget for direct costs of up to $760,000 per year. An applicant for the PHACS DOC may request a project period of up to 5 years and an expected first-year budget for direct costs of up to $12,400,000 per year (note: clinical site consortium indirect costs are included in direct cost line under subcontracts in DOC budget). Additional funds may become available from current co-sponsors or other NIH institutes. Eligible Institutions/Organizations. This is a limited solicitation made available to the grantees funded under the first PHACS RFA (HD-05-018) as a recompetition for an additional award of up to five years. Eligible Project Directors/Principal Investigators (PDs/PIs). Individuals with the skills, knowledge, and resources necessary to carry out the proposed research are invited to work with their institution/organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support.
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