OpportunityTitle: Tissue Mapping Centers for the Human BioMolecular Atlas Program (U54 Clinical Trial Not Allowed)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.  Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.  Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Description: This FOA seeks to support state-of-the-art Tissue Mapping Centers (TMCs) that will serve as the core data generators for the HuBMAP Consortium by generating a high-resolution, multi-parameter, 3D atlas of a non-diseased human organ. Successful centers will build, benchmark, and standardize pipelines for generating, validating and analyzing data from multiplexed, high-throughput imaging and omics technologies. Centers will be expected to integrate and optimize all parts of the data generation pipeline, from tissue collection and preservation through to data integration, analysis and interpretation in order to build high-resolution maps. Centers will use these maps to provide new insights into intra-, inter- and extra- cellular organizational features that influence tissue function, vary across individuals or that change across the lifespan. By the end of four years of funding, a successful center will have created a significant number of high-resolution, multi-scale, multi-dimensional molecular, cellular and morphological maps from multiple donors that are integrated into a published reference atlas for that organ.
GrantorContactEmailDescription: See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
GrantorContactText: NIH OER Webmaster&lt;br/&gt;OERWebmaster03@od.nih.gov