OpportunityTitle: Systems Biology of Aging (R01)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Description: This Funding Opportunity Announcement (FOA) encourages research projects with the potential to develop networks of aging using lifespan as the observable phenotype. In addition to constructing aging networks, two further important goals of this FOA are: 1. Determining what properties of an aging network change across the lifespan; 2. Using aging networks to generate and test hypotheses about fundamental questions in the biology of aging that are more likely to be answered using systems biology than by single-gene approaches. Research proposed in applications responding to this FOA will utilize either the single-cell organism Saccharomyces cerevisiae or the multicellular organism Caenorhabditis elegans, both of which have been used extensively for genetic and molecular studies on aging.Applications must include a contact PD/PI who is an expert in systems biology and other PD/PI(s) should have expertise in the biology of aging and/or necessary high-throughput technologies using the laboratory organism for study (S. cerevisiae or C. elegans, only).
GrantorContactEmailDescription: If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster
GrantorContactText: NIH OER Webmaster&lt;br/&gt;FBOWebmaster@OD.NIH.GOV&lt;br/&gt;