OpportunityTitle: Innovative Assays to Quantify the Latent HIV Reservoir (R01)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Description: The purpose of this Funding Opportunity Announcement (FOA) is to support research on new or improved methods for quantifying latently infected cells in HIV-positive individuals on effective antiretroviral therapy. Quantifying latent HIV reservoirs is critical to evaluating strategies to cure HIV infection in vivo. The current gold-standard method involves a limiting dilution viral outgrowth assay that is slow, resource-intensive, and relatively imprecise. A molecular assay to accurately detect replication-competent provirus, or a viral outgrowth assay with improved efficiency, would facilitate proof-of-concept studies for curing HIV infection.
GrantorContactEmailDescription: If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster
GrantorContactText: NIH OER Webmaster&lt;br/&gt;FBOWebmaster@OD.NIH.GOV&lt;br/&gt;