OpportunityTitle: Cardiac Translational Research Implementation Program (C-TRIP) (P20)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Description: -Purpose. The National Heart, Lung, and Blood Institute (NHLBI) solicits Stage 1 exploratory planning (P20) applications to the Cardiac Translational Research Implementation Program (C-TRIP).The overall objective of the entire two-staged C-TRIP is to accelerate translation of promising new therapeutic interventions derived from fundamental research discoveries for the treatment and prevention of heart failure or arrhythmias through the planning and execution of well-designed clinical trials to demonstrate safety and efficacy.Stage 1 exploratory planning (P20) applications will support the planning and development of Stage 2 specialized center (P50) applications that support the conduct of the safety and efficacy trials recommended for support following a second phase of peer review. Subsequent Stage 2 (P50) applications for the conduct of the clinical trials planned and developed during Stage 1 will be solicited at a later time.The to-be-released solicitation for Stage 2 specialized center (P50) applications will be limited to successful Stage 1 applicants. Stage 2 (P50) applications will be anticipated 18 months following the initial award of Stage 1 applications.Support during Stage 2 of C-TRIP is expected to provide up to $1,515,000 direct costs per year for up to five years.Only two-year, Stage 1 (P20) applications are being solicited at this time. -Budget and Project Period. The total project period for the Stage 1 exploratory planning (P20) applications submitted in response to the present C-TRIP announcement is two years.During this period, applicants may request no more than $500,000 per year in direct costs for a maximum of $1,000,000 direct costs. -Mechanism of Support.This FOA for Stage 1 C-TRIP applications will utilize the Exploratory Grants Mechanism (P20).
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