OpportunityTitle: Extracellular RNA Biogenesis, Biodistribution, Uptake, and Effector Function (U19)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.  Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Description: The NIH invites applications for projects to determine the principles that guide the selection of regulatory RNA molecules for extracellular transport and to determine the function of these extracellular RNAs (exRNAs). The main scientific areas of interest include (1) exRNA biogenesis, (2) exRNA biodistribution, (3) uptake of exRNA by target cells, and (4) the physiological impact of delivered exRNA in target cells and tissues. Enabling tools, technologies, bioreagents, and innovative analytical approaches will likely be required to achieve the research goals. Therefore, awards funded under this FOA are anticipated to involve research conducted by multidisciplinary teams of investigators and focus on the role of exRNA communication in health and disease.
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GrantorContactText: NIH OER Webmaster&lt;br/&gt;FBOWebmaster@OD.NIH.GOV&lt;br/&gt;