OpportunityTitle: Atopic Dermatitis Research Network (ADRN) (U19)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.  Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Description: This Funding Opportunity Announcement (FOA) solicits applications from institutions to administer a multi-project, multi-institution program to conduct clinical research and provide the leadership and administrative responsibilities for the Atopic Dermatitis Research Network (ADRN). The ADRN conducts clinical research studies to better understand host defense mechanisms in the skin, by comparing responses to infections and vaccines, and underlying mechanisms, in healthy, non-atopic individuals vs. those with atopic dermatitis (AD). Such effects include skin barrier and adaptive and innate immune system responses to viral and bacterial infections, and genetic and epigenetic studies. The scope of research supported under this FOA will include the role of the microbiome in regulating host defense, and the development of clinical interventions to enhance host defense. The FOA will also support the conduct of longitudinal studies aiming at the identification of AD phenotypes pertaining to clinical presentation, skin and peripheral blood immunologic responses and patterns of cutaneous host defense.
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GrantorContactText: NIH OER Webmaster&lt;br/&gt;FBOWebmaster@OD.NIH.GOV&lt;br/&gt;