OpportunityTitle: Caenorhabditis Intervention Testing Program (CITP)  U01
AdditionalInformationOnEligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.  Foreign components, as defined in the NIH Grants Policy Statement, are not allowed
Description: The National Institute on Aging (NIA) invites applications for cooperative agreements (U01s) from investigators or groups of investigators (e.g., multiple PD(s)/PI(s) capable of, and interested in, participating in a Caenorhabditis Intervention Testing Program (CITP). The goal is to identify pharmacological interventions that increase lifespan and/or healthspan in a robust manner when tested using multiple species of the simple invertebrate Caenorhabditis and/or multiple strains of Caenorhabditis elegans. Human populations are genetically heterogeneous and thus, in order to work in humans, any intervention that extends lifespan/healthspan needs to do so within a variety of genetic backgrounds. Testing of promising compounds in a variety of genetic backgrounds within a species with a short, well-studied lifespan and healthspan, should accelerate the current rate of discovery.
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GrantorContactText: NIH OER Webmaster&lt;br/&gt;FBOWebmaster@OD.NIH.GOV&lt;br/&gt;