OpportunityTitle: Approaches to Eliminate HIV and Opportunistic Pathogens from Oral Reservoirs (R01)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Foreign Institutions Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Description: The goal of this Funding Opportunity Announcement (FOA) is to support novel basic and translational research projects that focus on the biology of residual oral reservoirs for HIV and opportunistic oral pathogens.These studies will advance our understanding of the immunologic, pathogenic, molecular and cellular mechanisms important for eliminating latently persistent, reactivation competent HIV and other opportunistic pathogens from residual oral reservoirs.Specifically, this FOA encourages studies on: 1) purging and abolishing these pathogens after using Highly Active Anti-Retroviral Therapy (HAART) to induce cytopathic killing and immunoclearance; or 2) developing alternative strategies that directly eliminate latently infected cells in which HAART resistant HIV and opportunistic pathogens persist in oral reservoirs.
GrantorContactEmailDescription: If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster
GrantorContactText: NIH OER Webmaster&lt;br/&gt;FBOWebmaster@OD.NIH.GOV&lt;br/&gt;