OpportunityTitle: Epidemiology of Lupus:  Longitudinal Studies in Population-Based Cohorts
AdditionalInformationOnEligibility: Eligibility applicants must meet the following criteria:Component A: (Longitudinal Studies of Lupus in Population-based cohorts of Adults with Lupus: 3 Year Followup):Criteria 1. Applicant must have an existing U.S. population-based cohort with &amp;gt; 400 adults ages 18 and greater at baseline, with SLE and/or skin lupus.  Criteria 2. Applicant must have at least 4 years of followup at time of application for the four content areas listed in the Approach section above (natural history, treatment, health care access, and disparities).Component B: (A Pediatric Lupus Registry with Longitudinal Followup):Criteria 1. Applicant must have access to an existing cohort with 200+ diagnosed U.S. lupus patients ages 0-17 years at baseline in an area that is geographically population-based.If your application is incomplete or non-responsive to the special eligibility requirements listed in this section, it will not enter into the review process.
Description: This NOFO is intended to support research on lupus through a 2-component cooperative agreement:Component A (Longitudinal Studies in Population-based Cohorts of Adults with Lupus: 3 Year Followup):This is a longitudinal followup study designed to support an established, US-based, population-based cohort of adults age 18 and older with diagnosed lupus (systemic lupus erythematosus {SLE} and skin lupus) that includes followup data collected at least once since 2015. The intent of this study is to conduct data collection, building upon the cohort and initial followup activities. This data collection should include four content areas:The natural history (e.g., severity, morbidity, mortality, disability, comorbidity, work interference, etc.) of cohort members, andTreatment (e.g., medications, therapy, self-management, etc.) of lupus including the treatment of chronic pain and opioid use, andHealth care access and gaps that adults with lupus experience, andDisparities (e.g., age, race/ethnicity, sex) and other factors associated with lupus outcomes.Component B: (A Pediatric Lupus Registry with Longitudinal Follow up):This is a project that will support an existing US-based registry of children age 0-17 years with diagnosed lupus (SLE and skin lupus). The intent of this study is to gather baseline data for children age 0-17 years and follow up data for this cohort for three additional years. The baseline and follow up data should include these 4 content areas:The natural history (e.g., severity, morbidity, mortality, disability, comorbidity, work interference, etc.) of cohort members, andTreatment (e.g., medications, therapy, self-management, etc.) of lupus including the treatment of chronic pain and opioid use, andHealth care access and gaps that children with lupus experience, andDisparities (e.g., age, race/ethnicity, sex) and other factors associated with lupus outcomes.
GrantorContactEmailDescription: Grants Policy
GrantorContactText: Jessie Hood&lt;br/&gt;jvr4@cdc.gov
CloseDateExplanation: Electronically submitted applications must be submitted no later than 5:00 p.m., ET, on the listed application due date.