OpportunityTitle: Center of Excellence for Natural Product Drug Interaction Research (U54)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Foreign Institutions  Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Description: The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications for a Center of Excellence for Natural Product Drug Interaction Research to provide leadership in the study of natural product drug interactions. The ultimate goal of this program is to develop a definitive approach to determining the clinical relevance of pharmacokinetic interactions between natural products and medications.The Center will 1) identify, prioritize and source four to six natural products with potential to exhibit clinically significant interactions with commonly used medications; 2) work collaboratively with the NIH to develop and execute a statement of work for each of the selected natural products which will address existing gaps in the scientific literature and result in a definitive assessment regarding the clinical relevance of any pharmacokinetic interaction; 3) establish a set of best practices to address the unique challenges related to the study of natural product interactions with drugs; and 4) develop and maintain a database and public access portal for the data and methodology resources generated; thereby facilitating better design of future research and ultimately better decisions regarding the concomitant use of medications and natural products.
GrantorContactEmailDescription: If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster
GrantorContactText: NIH OER Webmaster&lt;br/&gt;FBOWebmaster@OD.NIH.GOV&lt;br/&gt;