OpportunityTitle: BD2K-LINCS-Perturbation Data Coordination and Integration Center (DCIC) (U54)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.  Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are  allowed.
Description: This FOA seeks applications to develop a data coordination and integration center (DCIC) that will address the opportunities and challenges provided by two major NIH efforts: Big Data to Knowledge (BD2K) and the Library of Integrated Network-Based Cellular Signatures (LINCS). The NIH expects that this BD2K-LINCS DCIC will focus on perturbagen-response data and signatures while ensuring that the resulting resources are effectively utilized by the community by addressing challenges related to biomedical Big Data. A successful DCIC will ensure consistent annotation of data and tools generated within the LINCS program; incorporate (without replicating databases) relevant non-LINCS perturbation data into the LINCS resource; support integration of relevant data, signatures, and tools to allow for seamless exploration of the (LINCS) programs output by a broad range of biomedical researchers; support linkages to outside knowledge bases, data portals, and resources; support training in perturbation-data science skills; build innovative access and query tools to disparate databases hosting multiple data types; and disseminate the resulting tools and resources to the broad range of biomedical researchers. Related FOAs of relevance to the DCIC include RFA-RM-13-013 soliciting applications for LINCS data and signature generation and RFA-HG-13-009 soliciting applications for BD2K Centers of Excellence.
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GrantorContactText: NIH OER Webmaster&lt;br/&gt;FBOWebmaster@OD.NIH.GOV&lt;br/&gt;