OpportunityTitle: Expanding the Encyclopedia of DNA Elements (ENCODE) in the Human and Mouse (UM1)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Description: The Encyclopedia of DNA Elements (ENCODE) Project has cataloged a significant number of candidate functional elements in the human and mouse (Mus musculus) genomes.These catalogs are being used by the research community to expand on basic biological knowledge, to develop research tools and to interpret the results of disease-mapping studies. Although much progress has been made over the past decade, these catalogs are incomplete. The purpose of this FOA is to solicit applications for research projects to apply state-of-the-art, high-throughput and cost-effective data generation pipelines to develop an expanded catalog of candidate functional elements in the human and mouse genomes.As part of this effort, applicants may map candidate elements in biological samples relevant to specific diseases to help expand the catalog while at the same time informing on how to direct disease studies in the long run. The funded projects will participate in the ENCODE Consortium.
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