OpportunityTitle: Novel Interventions for Neurodevelopmental Disorders (R21/R33)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Description: Purpose. This funding opportunity announcement (FOA) solicits Exploratory/Developmental Phased Innovation (R21/R33) grant applications that propose to develop novel interventions that will improve functioning in domains commonly affected by neurodevelopmental disorders. This FOA provides support for a first phase (R21) for initial technical development and proof-of-principle and a second phase (R33) for further development, application, and evaluation of clinical utility. It is intended that the results will support the development of larger efficacy studies of the proposed novel intervention. This FOA is intended to encourage a broad scope of new treatment approaches with potential for widespread, cost-effective application across a variety of neurodevelopmental disorders based on the targeted domain(s) of impairment. The treatment approaches may include psychopharmacologic, other physiological, cognitive, psychosocial, psychoeducational, and behavioral approaches or novel combinations of any of these approaches. Also of interest are particularly innovative and theoretically-based intervention approaches currently in clinical use that have not been adequately evaluated for safety and tolerability. Mechanism of Support. This FOA will utilize the NIH Exploratory/Developmental Phased Innovation (R21/R33) award mechanism and runs in parallel with an FOA of identical scientific scope, RFA-MH-09-160, which solicits applications under the R34 award mechanism. The R34 mechanism may be more appropriate when early conceptual work has been completed and proof-of-principle has been demonstrated.
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GrantorContactText: NIH OER Webmaster&lt;br/&gt;FBOWebmaster@OD.NIH.GOV&lt;br/&gt;