OpportunityTitle: NICHD Genomic Clinical Variant Expert Curation Panels (U24)
AdditionalInformationOnEligibility: Other Eligible Applicants include the following:  Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are  not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are  not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are  allowed.
Description: The objective of this FOA is to establish expert panels that will select genes and genomic variants associated with diseases or conditions of high priority to NICHD and systematically determine their clinical significance and utility for diagnosis and treatment of these diseases or conditions. The Genomic Clinical Variant Expert Curation Panels funded through this FOA are expected to utilize the NHGRI Clinical Genomics Resource (ClinGen) and the NCBI ClinVar tools and informatics infrastructure to determine the strength of evidence supporting the clinical significance or actionability of the selected genes and variants that will support development of clinical practice guidelines.
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GrantorContactText: NIH OER Webmaster&lt;br/&gt;FBOWebmaster@OD.NIH.GOV&lt;br/&gt;