2024-04-13 12:07:01,679::INFO::main: Starting joint PCA 2024-04-13 12:07:08,117::INFO::__init__: JointPCADecomposer :: configuration: ==================== Joint PCA Configuration ==================== mcools : - day00_ESC_pool.hg38.mapq_30.100.mcool - day02_mesoderm_pool.hg38.mapq_30.100.mcool - day05_cardiacMesoderm_pool.hg38.mapq_30.100.mcool - day07_cardiacProgenitor_pool.hg38.mapq_30.100.mcool - day15_primativeCardiomyocyte_pool.hg38.mapq_30.100.mcool - day80_ventricularCardiomyocyte_pool.hg38.mapq_30.100.mcool - DE-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool - DE_pool.hg38.mapq_30.100.mcool - ENCFF004YZQ.mcool - ENCFF009ONH.mcool - ENCFF019YVI.mcool - ENCFF029UAL.mcool - ENCFF035BLF.mcool - ENCFF044TCQ.mcool - ENCFF059WMS.mcool - ENCFF076LWH.mcool - ENCFF081PMO.mcool - ENCFF094KKX.mcool - ENCFF136XCV.mcool - ENCFF140ROU.mcool - ENCFF149IHN.mcool - ENCFF176LIZ.mcool - ENCFF185AYZ.mcool - ENCFF193CQL.mcool - ENCFF197OWW.mcool - ENCFF224HKR.mcool - ENCFF235LCO.mcool - ENCFF251VFA.mcool - ENCFF252ANV.mcool - ENCFF273XBU.mcool - ENCFF284OEA.mcool - ENCFF309UNV.mcool - ENCFF333WCK.mcool - ENCFF355NFJ.mcool - ENCFF355VJW.mcool - ENCFF395INO.mcool - ENCFF417GBZ.mcool - ENCFF442IGJ.mcool - ENCFF458VBB.mcool - ENCFF493SFI.mcool - ENCFF493YNC.mcool - ENCFF496GEU.mcool - ENCFF499BVX.mcool - ENCFF515ZBF.mcool - ENCFF520GFL.mcool - ENCFF545GBW.mcool - ENCFF556RLR.mcool - ENCFF558DYU.mcool - ENCFF571GTF.mcool - ENCFF579CAR.mcool - ENCFF586MQY.mcool - ENCFF591MHA.mcool - ENCFF605CEN.mcool - ENCFF614IPZ.mcool - ENCFF625VNK.mcool - ENCFF628LQQ.mcool - ENCFF653HCO.mcool - ENCFF654YIQ.mcool - ENCFF660JWA.mcool - ENCFF663FRL.mcool - ENCFF684YCT.mcool - ENCFF687ATD.mcool - ENCFF700CYI.mcool - ENCFF705YZH.mcool - ENCFF711XSR.mcool - ENCFF736ITL.mcool - ENCFF782WVZ.mcool - ENCFF783KQI.mcool - ENCFF791UZC.mcool - ENCFF839VMS.mcool - ENCFF842DUO.mcool - ENCFF883XXW.mcool - ENCFF897KRI.mcool - ENCFF911AHQ.mcool - ENCFF925QIF.mcool - ENCFF943JRY.mcool - ENCFF952JZV.mcool - ENCFF958DWQ.mcool - ENCFF962EDB.mcool - ENCFF965BPU.mcool - ENCFF980NXK.mcool - ESC-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool - HB-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool - hESC_pool.hg38.mapq_30.100.mcool - iHEP-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool - mHEP-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool - PGT_pool.hg38.mapq_30.100.mcool - PH_pool.hg38.mapq_30.100.mcool - PP_pool.hg38.mapq_30.100.mcool - SC_Beta_pool.hg38.mapq_30.100.mcool resolution : 50000 assembly : hg38 output : output_2024_04_13_12_07 components : 32 chrom_limit : 22 method : PCA exclusion_list : None percentile_top : 99.5 percentile_bottom : 1.0 batch_size : 10000 log_level : DEBUG =================================================================== 2024-04-13 12:07:08,136::INFO::get_chromosome_sizes: Loaded chromosome sizes for specified assembly: hg38 2024-04-13 12:07:08,136::INFO::get_chromosome_sizes: Chromosome sizes: name chr1 248956422 chr2 242193529 chr3 198295559 chr4 190214555 chr5 181538259 chr6 170805979 chr7 159345973 chr8 145138636 chr9 138394717 chr10 133797422 chr11 135086622 chr12 133275309 chr13 114364328 chr14 107043718 chr15 101991189 chr16 90338345 chr17 83257441 chr18 80373285 chr19 58617616 chr20 64444167 chr21 46709983 chr22 50818468 Name: length, dtype: int64 2024-04-13 12:07:08,136::INFO::set_union_bad_bins: Beginning to compute union set of NaN bins.. 2024-04-13 12:07:08,182::DEBUG::partition: Loading partitions for cooler: day00_ESC_pool.hg38.mapq_30.100.mcool::/resolutions/50000 2024-04-13 12:07:08,243::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:08,244::DEBUG::partition: Loading partitions for cooler: day02_mesoderm_pool.hg38.mapq_30.100.mcool::/resolutions/50000 2024-04-13 12:07:08,320::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:08,320::DEBUG::partition: Loading partitions for cooler: day05_cardiacMesoderm_pool.hg38.mapq_30.100.mcool::/resolutions/50000 2024-04-13 12:07:08,410::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:08,410::DEBUG::partition: Loading partitions for cooler: day07_cardiacProgenitor_pool.hg38.mapq_30.100.mcool::/resolutions/50000 2024-04-13 12:07:08,486::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:08,486::DEBUG::partition: Loading partitions for cooler: day15_primativeCardiomyocyte_pool.hg38.mapq_30.100.mcool::/resolutions/50000 2024-04-13 12:07:08,575::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:08,575::DEBUG::partition: Loading partitions for cooler: day80_ventricularCardiomyocyte_pool.hg38.mapq_30.100.mcool::/resolutions/50000 2024-04-13 12:07:08,630::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:08,630::DEBUG::partition: Loading partitions for cooler: DE-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool::/resolutions/50000 2024-04-13 12:07:08,686::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:08,686::DEBUG::partition: Loading partitions for cooler: DE_pool.hg38.mapq_30.100.mcool::/resolutions/50000 2024-04-13 12:07:09,278::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:09,278::DEBUG::partition: Loading partitions for cooler: ENCFF004YZQ.mcool::/resolutions/50000 2024-04-13 12:07:09,419::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:09,419::DEBUG::partition: Loading partitions for cooler: ENCFF009ONH.mcool::/resolutions/50000 2024-04-13 12:07:09,558::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:09,558::DEBUG::partition: Loading partitions for cooler: ENCFF019YVI.mcool::/resolutions/50000 2024-04-13 12:07:09,674::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:09,674::DEBUG::partition: Loading partitions for cooler: ENCFF029UAL.mcool::/resolutions/50000 2024-04-13 12:07:09,830::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:09,830::DEBUG::partition: Loading partitions for cooler: ENCFF035BLF.mcool::/resolutions/50000 2024-04-13 12:07:09,932::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:09,933::DEBUG::partition: Loading partitions for cooler: ENCFF044TCQ.mcool::/resolutions/50000 2024-04-13 12:07:10,043::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:10,043::DEBUG::partition: Loading partitions for cooler: ENCFF059WMS.mcool::/resolutions/50000 2024-04-13 12:07:10,157::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:10,157::DEBUG::partition: Loading partitions for cooler: ENCFF076LWH.mcool::/resolutions/50000 2024-04-13 12:07:10,314::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:10,314::DEBUG::partition: Loading partitions for cooler: ENCFF081PMO.mcool::/resolutions/50000 2024-04-13 12:07:10,445::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:10,445::DEBUG::partition: Loading partitions for cooler: ENCFF094KKX.mcool::/resolutions/50000 2024-04-13 12:07:10,564::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:10,564::DEBUG::partition: Loading partitions for cooler: ENCFF136XCV.mcool::/resolutions/50000 2024-04-13 12:07:10,661::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:10,661::DEBUG::partition: Loading partitions for cooler: ENCFF140ROU.mcool::/resolutions/50000 2024-04-13 12:07:10,775::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:10,775::DEBUG::partition: Loading partitions for cooler: ENCFF149IHN.mcool::/resolutions/50000 2024-04-13 12:07:10,892::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:10,892::DEBUG::partition: Loading partitions for cooler: ENCFF176LIZ.mcool::/resolutions/50000 2024-04-13 12:07:11,024::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:11,024::DEBUG::partition: Loading partitions for cooler: ENCFF185AYZ.mcool::/resolutions/50000 2024-04-13 12:07:11,173::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:11,173::DEBUG::partition: Loading partitions for cooler: ENCFF193CQL.mcool::/resolutions/50000 2024-04-13 12:07:11,278::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:11,278::DEBUG::partition: Loading partitions for cooler: ENCFF197OWW.mcool::/resolutions/50000 2024-04-13 12:07:11,428::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:11,428::DEBUG::partition: Loading partitions for cooler: ENCFF224HKR.mcool::/resolutions/50000 2024-04-13 12:07:11,537::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:11,537::DEBUG::partition: Loading partitions for cooler: ENCFF235LCO.mcool::/resolutions/50000 2024-04-13 12:07:11,653::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:11,653::DEBUG::partition: Loading partitions for cooler: ENCFF251VFA.mcool::/resolutions/50000 2024-04-13 12:07:11,811::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:11,811::DEBUG::partition: Loading partitions for cooler: ENCFF252ANV.mcool::/resolutions/50000 2024-04-13 12:07:11,966::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:11,966::DEBUG::partition: Loading partitions for cooler: ENCFF273XBU.mcool::/resolutions/50000 2024-04-13 12:07:12,104::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:12,104::DEBUG::partition: Loading partitions for cooler: ENCFF284OEA.mcool::/resolutions/50000 2024-04-13 12:07:12,245::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:12,245::DEBUG::partition: Loading partitions for cooler: ENCFF309UNV.mcool::/resolutions/50000 2024-04-13 12:07:12,361::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:12,361::DEBUG::partition: Loading partitions for cooler: ENCFF333WCK.mcool::/resolutions/50000 2024-04-13 12:07:12,490::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:12,490::DEBUG::partition: Loading partitions for cooler: ENCFF355NFJ.mcool::/resolutions/50000 2024-04-13 12:07:12,669::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:12,669::DEBUG::partition: Loading partitions for cooler: ENCFF355VJW.mcool::/resolutions/50000 2024-04-13 12:07:12,815::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:12,815::DEBUG::partition: Loading partitions for cooler: ENCFF395INO.mcool::/resolutions/50000 2024-04-13 12:07:12,978::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:12,978::DEBUG::partition: Loading partitions for cooler: ENCFF417GBZ.mcool::/resolutions/50000 2024-04-13 12:07:13,089::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:13,089::DEBUG::partition: Loading partitions for cooler: ENCFF442IGJ.mcool::/resolutions/50000 2024-04-13 12:07:13,210::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:13,210::DEBUG::partition: Loading partitions for cooler: ENCFF458VBB.mcool::/resolutions/50000 2024-04-13 12:07:13,387::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:13,387::DEBUG::partition: Loading partitions for cooler: ENCFF493SFI.mcool::/resolutions/50000 2024-04-13 12:07:13,525::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:13,525::DEBUG::partition: Loading partitions for cooler: ENCFF493YNC.mcool::/resolutions/50000 2024-04-13 12:07:13,659::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:13,659::DEBUG::partition: Loading partitions for cooler: ENCFF496GEU.mcool::/resolutions/50000 2024-04-13 12:07:13,804::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:13,804::DEBUG::partition: Loading partitions for cooler: ENCFF499BVX.mcool::/resolutions/50000 2024-04-13 12:07:13,960::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:13,960::DEBUG::partition: Loading partitions for cooler: ENCFF515ZBF.mcool::/resolutions/50000 2024-04-13 12:07:14,110::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:14,110::DEBUG::partition: Loading partitions for cooler: ENCFF520GFL.mcool::/resolutions/50000 2024-04-13 12:07:14,223::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:14,223::DEBUG::partition: Loading partitions for cooler: ENCFF545GBW.mcool::/resolutions/50000 2024-04-13 12:07:14,383::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:14,384::DEBUG::partition: Loading partitions for cooler: ENCFF556RLR.mcool::/resolutions/50000 2024-04-13 12:07:14,529::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:14,529::DEBUG::partition: Loading partitions for cooler: ENCFF558DYU.mcool::/resolutions/50000 2024-04-13 12:07:14,772::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:14,772::DEBUG::partition: Loading partitions for cooler: ENCFF571GTF.mcool::/resolutions/50000 2024-04-13 12:07:14,890::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:14,890::DEBUG::partition: Loading partitions for cooler: ENCFF579CAR.mcool::/resolutions/50000 2024-04-13 12:07:15,021::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:15,021::DEBUG::partition: Loading partitions for cooler: ENCFF586MQY.mcool::/resolutions/50000 2024-04-13 12:07:15,173::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:15,173::DEBUG::partition: Loading partitions for cooler: ENCFF591MHA.mcool::/resolutions/50000 2024-04-13 12:07:15,277::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:15,277::DEBUG::partition: Loading partitions for cooler: ENCFF605CEN.mcool::/resolutions/50000 2024-04-13 12:07:15,390::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:15,390::DEBUG::partition: Loading partitions for cooler: ENCFF614IPZ.mcool::/resolutions/50000 2024-04-13 12:07:15,509::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:15,509::DEBUG::partition: Loading partitions for cooler: ENCFF625VNK.mcool::/resolutions/50000 2024-04-13 12:07:15,661::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:15,661::DEBUG::partition: Loading partitions for cooler: ENCFF628LQQ.mcool::/resolutions/50000 2024-04-13 12:07:15,870::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:15,870::DEBUG::partition: Loading partitions for cooler: ENCFF653HCO.mcool::/resolutions/50000 2024-04-13 12:07:16,001::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:16,001::DEBUG::partition: Loading partitions for cooler: ENCFF654YIQ.mcool::/resolutions/50000 2024-04-13 12:07:16,144::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:16,144::DEBUG::partition: Loading partitions for cooler: ENCFF660JWA.mcool::/resolutions/50000 2024-04-13 12:07:16,233::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:16,233::DEBUG::partition: Loading partitions for cooler: ENCFF663FRL.mcool::/resolutions/50000 2024-04-13 12:07:16,388::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:16,388::DEBUG::partition: Loading partitions for cooler: ENCFF684YCT.mcool::/resolutions/50000 2024-04-13 12:07:16,509::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:16,509::DEBUG::partition: Loading partitions for cooler: ENCFF687ATD.mcool::/resolutions/50000 2024-04-13 12:07:16,678::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:16,678::DEBUG::partition: Loading partitions for cooler: ENCFF700CYI.mcool::/resolutions/50000 2024-04-13 12:07:16,824::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:16,824::DEBUG::partition: Loading partitions for cooler: ENCFF705YZH.mcool::/resolutions/50000 2024-04-13 12:07:16,983::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:16,983::DEBUG::partition: Loading partitions for cooler: ENCFF711XSR.mcool::/resolutions/50000 2024-04-13 12:07:17,123::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:17,124::DEBUG::partition: Loading partitions for cooler: ENCFF736ITL.mcool::/resolutions/50000 2024-04-13 12:07:17,222::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:17,222::DEBUG::partition: Loading partitions for cooler: ENCFF782WVZ.mcool::/resolutions/50000 2024-04-13 12:07:17,374::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:17,374::DEBUG::partition: Loading partitions for cooler: ENCFF783KQI.mcool::/resolutions/50000 2024-04-13 12:07:17,494::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:17,495::DEBUG::partition: Loading partitions for cooler: ENCFF791UZC.mcool::/resolutions/50000 2024-04-13 12:07:17,602::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:17,602::DEBUG::partition: Loading partitions for cooler: ENCFF839VMS.mcool::/resolutions/50000 2024-04-13 12:07:17,740::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:17,740::DEBUG::partition: Loading partitions for cooler: ENCFF842DUO.mcool::/resolutions/50000 2024-04-13 12:07:17,897::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:17,897::DEBUG::partition: Loading partitions for cooler: ENCFF883XXW.mcool::/resolutions/50000 2024-04-13 12:07:18,025::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:18,025::DEBUG::partition: Loading partitions for cooler: ENCFF897KRI.mcool::/resolutions/50000 2024-04-13 12:07:18,248::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:18,248::DEBUG::partition: Loading partitions for cooler: ENCFF911AHQ.mcool::/resolutions/50000 2024-04-13 12:07:18,374::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:18,374::DEBUG::partition: Loading partitions for cooler: ENCFF925QIF.mcool::/resolutions/50000 2024-04-13 12:07:18,495::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:18,495::DEBUG::partition: Loading partitions for cooler: ENCFF943JRY.mcool::/resolutions/50000 2024-04-13 12:07:18,599::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:18,600::DEBUG::partition: Loading partitions for cooler: ENCFF952JZV.mcool::/resolutions/50000 2024-04-13 12:07:18,742::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:18,742::DEBUG::partition: Loading partitions for cooler: ENCFF958DWQ.mcool::/resolutions/50000 2024-04-13 12:07:18,921::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:18,921::DEBUG::partition: Loading partitions for cooler: ENCFF962EDB.mcool::/resolutions/50000 2024-04-13 12:07:19,046::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:19,046::DEBUG::partition: Loading partitions for cooler: ENCFF965BPU.mcool::/resolutions/50000 2024-04-13 12:07:19,149::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:19,149::DEBUG::partition: Loading partitions for cooler: ENCFF980NXK.mcool::/resolutions/50000 2024-04-13 12:07:19,281::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:19,281::DEBUG::partition: Loading partitions for cooler: ESC-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool::/resolutions/50000 2024-04-13 12:07:19,408::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:19,408::DEBUG::partition: Loading partitions for cooler: HB-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool::/resolutions/50000 2024-04-13 12:07:19,853::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:19,853::DEBUG::partition: Loading partitions for cooler: hESC_pool.hg38.mapq_30.100.mcool::/resolutions/50000 2024-04-13 12:07:20,381::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:20,381::DEBUG::partition: Loading partitions for cooler: iHEP-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool::/resolutions/50000 2024-04-13 12:07:20,755::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:20,755::DEBUG::partition: Loading partitions for cooler: mHEP-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool::/resolutions/50000 2024-04-13 12:07:21,321::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:21,321::DEBUG::partition: Loading partitions for cooler: PGT_pool.hg38.mapq_30.100.mcool::/resolutions/50000 2024-04-13 12:07:22,035::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:22,035::DEBUG::partition: Loading partitions for cooler: PH_pool.hg38.mapq_30.100.mcool::/resolutions/50000 2024-04-13 12:07:22,702::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:22,702::DEBUG::partition: Loading partitions for cooler: PP_pool.hg38.mapq_30.100.mcool::/resolutions/50000 2024-04-13 12:07:23,295::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:23,295::DEBUG::partition: Loading partitions for cooler: SC_Beta_pool.hg38.mapq_30.100.mcool::/resolutions/50000 2024-04-13 12:07:23,923::DEBUG::partition: Loaded partitions: [0, 4980, 9824, 13790, 17595, 21226, 24643, 27830, 30733, 33501, 36177, 38879, 41545, 43833, 45974, 48014, 49821, 51487, 53095, 54268, 55557, 56492, 57509] 2024-04-13 12:07:23,965::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'day00_ESC_pool.hg38.mapq_30.100.mcool' with shape '(57509, 4)'. 2024-04-13 12:07:23,965::DEBUG::set_union_bad_bins: Percent bad bins: 10.98958423898868. 2024-04-13 12:07:24,000::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'day02_mesoderm_pool.hg38.mapq_30.100.mcool' with shape '(57509, 4)'. 2024-04-13 12:07:24,000::DEBUG::set_union_bad_bins: Percent bad bins: 11.000017388582657. 2024-04-13 12:07:24,064::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'day05_cardiacMesoderm_pool.hg38.mapq_30.100.mcool' with shape '(57509, 4)'. 2024-04-13 12:07:24,065::DEBUG::set_union_bad_bins: Percent bad bins: 11.017405971239285. 2024-04-13 12:07:24,094::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'day07_cardiacProgenitor_pool.hg38.mapq_30.100.mcool' with shape '(57509, 4)'. 2024-04-13 12:07:24,095::DEBUG::set_union_bad_bins: Percent bad bins: 11.119998608913388. 2024-04-13 12:07:24,151::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'day15_primativeCardiomyocyte_pool.hg38.mapq_30.100.mcool' with shape '(57509, 4)'. 2024-04-13 12:07:24,151::DEBUG::set_union_bad_bins: Percent bad bins: 11.318228451198943. 2024-04-13 12:07:24,208::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'day80_ventricularCardiomyocyte_pool.hg38.mapq_30.100.mcool' with shape '(57509, 4)'. 2024-04-13 12:07:24,209::DEBUG::set_union_bad_bins: Percent bad bins: 11.32344502599593. 2024-04-13 12:07:24,253::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'DE-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool' with shape '(57509, 4)'. 2024-04-13 12:07:24,254::DEBUG::set_union_bad_bins: Percent bad bins: 11.76337616720861. 2024-04-13 12:07:24,269::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'DE_pool.hg38.mapq_30.100.mcool' with shape '(57509, 4)'. 2024-04-13 12:07:24,269::DEBUG::set_union_bad_bins: Percent bad bins: 11.88857396233633. 2024-04-13 12:07:24,814::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF004YZQ.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:24,814::DEBUG::set_union_bad_bins: Percent bad bins: 11.905962544992958. 2024-04-13 12:07:25,372::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF009ONH.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:25,373::DEBUG::set_union_bad_bins: Percent bad bins: 11.984211166947782. 2024-04-13 12:07:25,886::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF019YVI.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:25,887::DEBUG::set_union_bad_bins: Percent bad bins: 11.987688883479107. 2024-04-13 12:07:26,178::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF029UAL.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:26,178::DEBUG::set_union_bad_bins: Percent bad bins: 12.039854631448991. 2024-04-13 12:07:26,736::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF035BLF.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:26,736::DEBUG::set_union_bad_bins: Percent bad bins: 12.5858561268671. 2024-04-13 12:07:27,231::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF044TCQ.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:27,231::DEBUG::set_union_bad_bins: Percent bad bins: 12.591072701664087. 2024-04-13 12:07:27,745::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF059WMS.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:27,746::DEBUG::set_union_bad_bins: Percent bad bins: 12.8379905753882. 2024-04-13 12:07:27,994::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF076LWH.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:27,995::DEBUG::set_union_bad_bins: Percent bad bins: 12.874506598967118. 2024-04-13 12:07:28,263::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF081PMO.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:28,263::DEBUG::set_union_bad_bins: Percent bad bins: 12.879723173764107. 2024-04-13 12:07:28,526::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF094KKX.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:28,526::DEBUG::set_union_bad_bins: Percent bad bins: 12.90754490601471. 2024-04-13 12:07:28,848::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF136XCV.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:28,848::DEBUG::set_union_bad_bins: Percent bad bins: 12.9127614808117. 2024-04-13 12:07:29,090::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF140ROU.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:29,090::DEBUG::set_union_bad_bins: Percent bad bins: 12.9127614808117. 2024-04-13 12:07:29,560::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF149IHN.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:29,561::DEBUG::set_union_bad_bins: Percent bad bins: 12.937105496530977. 2024-04-13 12:07:29,795::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF176LIZ.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:29,795::DEBUG::set_union_bad_bins: Percent bad bins: 12.937105496530977. 2024-04-13 12:07:30,098::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF185AYZ.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:30,098::DEBUG::set_union_bad_bins: Percent bad bins: 12.944060929593629. 2024-04-13 12:07:30,336::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF193CQL.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:30,336::DEBUG::set_union_bad_bins: Percent bad bins: 12.945799787859292. 2024-04-13 12:07:30,559::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF197OWW.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:30,560::DEBUG::set_union_bad_bins: Percent bad bins: 12.947538646124954. 2024-04-13 12:07:31,097::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF224HKR.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:31,097::DEBUG::set_union_bad_bins: Percent bad bins: 12.949277504390617. 2024-04-13 12:07:31,318::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF235LCO.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:31,318::DEBUG::set_union_bad_bins: Percent bad bins: 13.105774748300266. 2024-04-13 12:07:31,519::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF251VFA.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:31,519::DEBUG::set_union_bad_bins: Percent bad bins: 13.107513606565929. 2024-04-13 12:07:31,789::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF252ANV.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:31,789::DEBUG::set_union_bad_bins: Percent bad bins: 13.107513606565929. 2024-04-13 12:07:32,007::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF273XBU.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:32,008::DEBUG::set_union_bad_bins: Percent bad bins: 13.107513606565929. 2024-04-13 12:07:32,216::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF284OEA.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:32,216::DEBUG::set_union_bad_bins: Percent bad bins: 13.110991323097254. 2024-04-13 12:07:32,469::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF309UNV.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:32,469::DEBUG::set_union_bad_bins: Percent bad bins: 13.110991323097254. 2024-04-13 12:07:32,749::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF333WCK.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:32,749::DEBUG::set_union_bad_bins: Percent bad bins: 13.110991323097254. 2024-04-13 12:07:32,913::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF355NFJ.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:32,913::DEBUG::set_union_bad_bins: Percent bad bins: 13.121424472691231. 2024-04-13 12:07:33,144::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF355VJW.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:33,144::DEBUG::set_union_bad_bins: Percent bad bins: 13.123163330956894. 2024-04-13 12:07:33,672::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF395INO.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:33,672::DEBUG::set_union_bad_bins: Percent bad bins: 13.123163330956894. 2024-04-13 12:07:33,975::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF417GBZ.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:33,975::DEBUG::set_union_bad_bins: Percent bad bins: 13.142290771879184. 2024-04-13 12:07:34,497::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF442IGJ.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:34,498::DEBUG::set_union_bad_bins: Percent bad bins: 13.159679354535811. 2024-04-13 12:07:34,731::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF458VBB.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:34,732::DEBUG::set_union_bad_bins: Percent bad bins: 13.159679354535811. 2024-04-13 12:07:35,312::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF493SFI.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:35,312::DEBUG::set_union_bad_bins: Percent bad bins: 13.161418212801475. 2024-04-13 12:07:35,545::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF493YNC.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:35,546::DEBUG::set_union_bad_bins: Percent bad bins: 13.161418212801475. 2024-04-13 12:07:35,821::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF496GEU.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:35,822::DEBUG::set_union_bad_bins: Percent bad bins: 13.161418212801475. 2024-04-13 12:07:36,104::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF499BVX.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:36,104::DEBUG::set_union_bad_bins: Percent bad bins: 13.161418212801475. 2024-04-13 12:07:36,364::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF515ZBF.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:36,364::DEBUG::set_union_bad_bins: Percent bad bins: 13.161418212801475. 2024-04-13 12:07:36,635::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF520GFL.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:36,635::DEBUG::set_union_bad_bins: Percent bad bins: 13.170112504129788. 2024-04-13 12:07:36,928::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF545GBW.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:36,928::DEBUG::set_union_bad_bins: Percent bad bins: 13.170112504129788. 2024-04-13 12:07:37,446::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF556RLR.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:37,446::DEBUG::set_union_bad_bins: Percent bad bins: 13.204889669443043. 2024-04-13 12:07:37,675::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF558DYU.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:37,675::DEBUG::set_union_bad_bins: Percent bad bins: 13.204889669443043. 2024-04-13 12:07:38,209::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF571GTF.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:38,209::DEBUG::set_union_bad_bins: Percent bad bins: 13.204889669443043. 2024-04-13 12:07:38,422::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF579CAR.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:38,422::DEBUG::set_union_bad_bins: Percent bad bins: 13.222278252099672. 2024-04-13 12:07:38,723::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF586MQY.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:38,723::DEBUG::set_union_bad_bins: Percent bad bins: 13.225755968630997. 2024-04-13 12:07:38,908::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF591MHA.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:38,909::DEBUG::set_union_bad_bins: Percent bad bins: 13.225755968630997. 2024-04-13 12:07:39,480::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF605CEN.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:39,480::DEBUG::set_union_bad_bins: Percent bad bins: 13.225755968630997. 2024-04-13 12:07:39,731::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF614IPZ.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:39,732::DEBUG::set_union_bad_bins: Percent bad bins: 13.225755968630997. 2024-04-13 12:07:40,081::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF625VNK.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:40,082::DEBUG::set_union_bad_bins: Percent bad bins: 13.225755968630997. 2024-04-13 12:07:40,326::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF628LQQ.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:40,326::DEBUG::set_union_bad_bins: Percent bad bins: 13.225755968630997. 2024-04-13 12:07:40,547::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF653HCO.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:40,547::DEBUG::set_union_bad_bins: Percent bad bins: 13.225755968630997. 2024-04-13 12:07:40,767::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF654YIQ.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:40,767::DEBUG::set_union_bad_bins: Percent bad bins: 13.34747604722739. 2024-04-13 12:07:41,307::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF660JWA.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:41,308::DEBUG::set_union_bad_bins: Percent bad bins: 13.34747604722739. 2024-04-13 12:07:41,552::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF663FRL.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:41,553::DEBUG::set_union_bad_bins: Percent bad bins: 13.34747604722739. 2024-04-13 12:07:41,780::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF684YCT.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:41,780::DEBUG::set_union_bad_bins: Percent bad bins: 13.363125771618355. 2024-04-13 12:07:41,957::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF687ATD.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:41,958::DEBUG::set_union_bad_bins: Percent bad bins: 13.364864629884018. 2024-04-13 12:07:42,160::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF700CYI.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:42,160::DEBUG::set_union_bad_bins: Percent bad bins: 13.364864629884018. 2024-04-13 12:07:42,447::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF705YZH.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:42,448::DEBUG::set_union_bad_bins: Percent bad bins: 13.38399207080631. 2024-04-13 12:07:42,663::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF711XSR.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:42,663::DEBUG::set_union_bad_bins: Percent bad bins: 13.38399207080631. 2024-04-13 12:07:43,131::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF736ITL.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:43,132::DEBUG::set_union_bad_bins: Percent bad bins: 13.387469787337634. 2024-04-13 12:07:43,355::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF782WVZ.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:43,355::DEBUG::set_union_bad_bins: Percent bad bins: 13.387469787337634. 2024-04-13 12:07:43,610::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF783KQI.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:43,610::DEBUG::set_union_bad_bins: Percent bad bins: 13.387469787337634. 2024-04-13 12:07:43,852::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF791UZC.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:43,852::DEBUG::set_union_bad_bins: Percent bad bins: 13.387469787337634. 2024-04-13 12:07:44,427::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF839VMS.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:44,427::DEBUG::set_union_bad_bins: Percent bad bins: 13.389208645603297. 2024-04-13 12:07:44,711::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF842DUO.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:44,712::DEBUG::set_union_bad_bins: Percent bad bins: 13.389208645603297. 2024-04-13 12:07:45,029::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF883XXW.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:45,029::DEBUG::set_union_bad_bins: Percent bad bins: 13.389208645603297. 2024-04-13 12:07:45,285::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF897KRI.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:45,285::DEBUG::set_union_bad_bins: Percent bad bins: 13.389208645603297. 2024-04-13 12:07:45,470::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF911AHQ.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:45,471::DEBUG::set_union_bad_bins: Percent bad bins: 13.589177346154514. 2024-04-13 12:07:45,711::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF925QIF.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:45,711::DEBUG::set_union_bad_bins: Percent bad bins: 13.589177346154514. 2024-04-13 12:07:45,938::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF943JRY.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:45,938::DEBUG::set_union_bad_bins: Percent bad bins: 13.608304787076806. 2024-04-13 12:07:46,116::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF952JZV.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:46,116::DEBUG::set_union_bad_bins: Percent bad bins: 13.616999078405119. 2024-04-13 12:07:46,304::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF958DWQ.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:46,304::DEBUG::set_union_bad_bins: Percent bad bins: 13.66220939331235. 2024-04-13 12:07:46,478::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF962EDB.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:46,478::DEBUG::set_union_bad_bins: Percent bad bins: 13.665687109843677. 2024-04-13 12:07:46,673::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF965BPU.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:46,673::DEBUG::set_union_bad_bins: Percent bad bins: 13.665687109843677. 2024-04-13 12:07:46,861::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ENCFF980NXK.mcool' with shape '(57509, 9)'. 2024-04-13 12:07:46,861::DEBUG::set_union_bad_bins: Percent bad bins: 13.665687109843677. 2024-04-13 12:07:46,938::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'ESC-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool' with shape '(57509, 4)'. 2024-04-13 12:07:46,939::DEBUG::set_union_bad_bins: Percent bad bins: 13.695247700359944. 2024-04-13 12:07:46,978::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'HB-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool' with shape '(57509, 4)'. 2024-04-13 12:07:46,978::DEBUG::set_union_bad_bins: Percent bad bins: 13.863916952129232. 2024-04-13 12:07:46,992::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'hESC_pool.hg38.mapq_30.100.mcool' with shape '(57509, 4)'. 2024-04-13 12:07:46,992::DEBUG::set_union_bad_bins: Percent bad bins: 13.88130553478586. 2024-04-13 12:07:47,036::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'iHEP-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool' with shape '(57509, 4)'. 2024-04-13 12:07:47,037::DEBUG::set_union_bad_bins: Percent bad bins: 13.923038133161766. 2024-04-13 12:07:47,073::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'mHEP-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool' with shape '(57509, 4)'. 2024-04-13 12:07:47,073::DEBUG::set_union_bad_bins: Percent bad bins: 13.928254707958754. 2024-04-13 12:07:47,087::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'PGT_pool.hg38.mapq_30.100.mcool' with shape '(57509, 4)'. 2024-04-13 12:07:47,087::DEBUG::set_union_bad_bins: Percent bad bins: 13.933471282755743. 2024-04-13 12:07:47,100::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'PH_pool.hg38.mapq_30.100.mcool' with shape '(57509, 4)'. 2024-04-13 12:07:47,101::DEBUG::set_union_bad_bins: Percent bad bins: 13.947382148881045. 2024-04-13 12:07:47,114::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'PP_pool.hg38.mapq_30.100.mcool' with shape '(57509, 4)'. 2024-04-13 12:07:47,114::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 12:07:47,127::DEBUG::set_union_bad_bins: Loaded bins from cooler file 'SC_Beta_pool.hg38.mapq_30.100.mcool' with shape '(57509, 4)'. 2024-04-13 12:07:47,127::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 12:11:57,916::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:04:10.788637. 2024-04-13 12:12:01,098::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 12:19:35,032::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:37.115259. 2024-04-13 12:19:47,035::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (48977, 48977) 2024-04-13 12:19:47,095::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 12:20:34,453::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:47.358688. 2024-04-13 12:20:37,449::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 12:27:26,612::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:52.158616. 2024-04-13 12:27:38,695::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (48755, 48755) 2024-04-13 12:27:38,755::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 12:28:36,023::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:57.267725. 2024-04-13 12:28:39,078::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 12:35:10,397::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:34.374725. 2024-04-13 12:35:22,334::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (48606, 48606) 2024-04-13 12:35:22,393::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 12:36:11,828::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:49.435003. 2024-04-13 12:36:14,830::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 12:42:59,254::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:47.425426. 2024-04-13 12:43:11,102::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (48524, 48524) 2024-04-13 12:43:11,160::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 12:43:51,603::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:40.442573. 2024-04-13 12:43:54,589::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 12:51:11,616::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:20.013008. 2024-04-13 12:51:23,400::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (48357, 48357) 2024-04-13 12:51:23,458::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 12:52:09,528::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:46.070263. 2024-04-13 12:52:12,505::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 12:59:43,955::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:34.426600. 2024-04-13 12:59:55,735::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (48249, 48249) 2024-04-13 12:59:55,793::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 13:00:32,131::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:36.337321. 2024-04-13 13:00:35,153::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 13:07:36,654::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:04.523065. 2024-04-13 13:07:48,429::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (48091, 48091) 2024-04-13 13:07:48,486::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 13:08:10,403::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:21.916723. 2024-04-13 13:08:13,422::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 13:15:05,831::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:55.427700. 2024-04-13 13:15:17,776::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (48011, 48011) 2024-04-13 13:15:17,833::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 13:16:35,286::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:01:17.452357. 2024-04-13 13:16:38,391::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 13:23:42,850::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:07.563884. 2024-04-13 13:23:54,761::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (47772, 47772) 2024-04-13 13:23:54,818::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 13:24:33,238::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:38.419761. 2024-04-13 13:24:36,293::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 13:31:23,746::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:50.507428. 2024-04-13 13:31:35,279::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (47533, 47533) 2024-04-13 13:31:35,336::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 13:32:23,493::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:48.157128. 2024-04-13 13:32:26,487::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 13:39:27,862::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:04.369102. 2024-04-13 13:39:39,688::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (47381, 47381) 2024-04-13 13:39:39,744::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 13:40:37,089::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:57.345641. 2024-04-13 13:40:40,148::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 13:47:23,933::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:46.843021. 2024-04-13 13:47:35,579::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (47269, 47269) 2024-04-13 13:47:35,635::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 13:48:42,747::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:01:07.110980. 2024-04-13 13:48:45,839::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 13:55:30,284::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:47.537113. 2024-04-13 13:55:41,906::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (47151, 47151) 2024-04-13 13:55:41,968::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 13:56:17,391::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:35.422372. 2024-04-13 13:56:20,436::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 14:03:43,555::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:26.163841. 2024-04-13 14:03:55,028::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (46919, 46919) 2024-04-13 14:03:55,082::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 14:04:31,355::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:36.272388. 2024-04-13 14:04:34,424::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 14:12:04,583::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:33.227662. 2024-04-13 14:12:16,071::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (46890, 46890) 2024-04-13 14:12:16,126::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 14:13:06,882::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:50.755398. 2024-04-13 14:13:09,937::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 14:19:53,402::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:46.519768. 2024-04-13 14:20:04,884::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (46683, 46683) 2024-04-13 14:20:04,945::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 14:21:09,043::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:01:04.097859. 2024-04-13 14:21:12,105::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 14:28:06,208::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:57.165211. 2024-04-13 14:28:17,605::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (46555, 46555) 2024-04-13 14:28:17,659::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 14:29:11,426::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:53.766849. 2024-04-13 14:29:14,496::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 14:35:48,252::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:36.825802. 2024-04-13 14:35:59,654::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (46505, 46505) 2024-04-13 14:35:59,707::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 14:36:51,603::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:51.895636. 2024-04-13 14:36:54,669::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 14:43:47,094::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:55.491046. 2024-04-13 14:43:58,382::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (46405, 46405) 2024-04-13 14:43:58,435::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 14:44:52,774::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:54.338548. 2024-04-13 14:44:55,835::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 14:51:44,274::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:51.499924. 2024-04-13 14:51:55,410::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (46381, 46381) 2024-04-13 14:51:55,463::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 14:52:29,483::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:34.019693. 2024-04-13 14:52:32,515::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 14:59:37,267::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:07.783793. 2024-04-13 14:59:48,633::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (46378, 46378) 2024-04-13 14:59:48,686::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 15:00:36,171::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:47.484505. 2024-04-13 15:00:39,225::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 15:07:19,875::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:43.703452. 2024-04-13 15:07:31,078::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (46358, 46358) 2024-04-13 15:07:31,132::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 15:08:17,405::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:46.273031. 2024-04-13 15:08:20,430::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 15:15:33,333::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:15.927280. 2024-04-13 15:15:44,505::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (46085, 46085) 2024-04-13 15:15:44,557::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 15:16:51,940::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:01:07.382404. 2024-04-13 15:16:55,031::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 15:23:19,163::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:27.222971. 2024-04-13 15:23:30,426::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45965, 45965) 2024-04-13 15:23:30,479::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 15:24:21,633::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:51.153985. 2024-04-13 15:24:24,671::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 15:31:05,495::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:43.862242. 2024-04-13 15:31:16,477::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45910, 45910) 2024-04-13 15:31:16,529::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 15:32:03,320::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:46.790411. 2024-04-13 15:32:06,325::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 15:39:13,811::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:10.490467. 2024-04-13 15:39:24,993::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45899, 45899) 2024-04-13 15:39:25,045::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 15:40:16,209::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:51.163086. 2024-04-13 15:40:19,294::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 15:47:29,439::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:13.229891. 2024-04-13 15:47:40,549::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45894, 45894) 2024-04-13 15:47:40,609::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 15:48:34,139::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:53.529880. 2024-04-13 15:48:37,200::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 15:55:05,998::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:31.859185. 2024-04-13 15:55:16,981::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45888, 45888) 2024-04-13 15:55:17,040::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 15:56:05,277::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:48.236866. 2024-04-13 15:56:08,297::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 16:03:00,803::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:55.525278. 2024-04-13 16:03:11,764::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45872, 45872) 2024-04-13 16:03:11,816::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 16:04:09,323::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:57.506850. 2024-04-13 16:04:12,347::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 16:10:53,106::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:43.782456. 2024-04-13 16:11:04,077::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45869, 45869) 2024-04-13 16:11:04,129::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 16:12:03,924::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:59.794697. 2024-04-13 16:12:06,953::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 16:18:34,200::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:30.275376. 2024-04-13 16:18:45,164::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45819, 45819) 2024-04-13 16:18:45,216::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 16:19:48,660::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:01:03.443698. 2024-04-13 16:19:51,746::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 16:26:45,791::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:57.131218. 2024-04-13 16:26:56,734::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45735, 45735) 2024-04-13 16:26:56,786::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 16:28:04,150::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:01:07.363702. 2024-04-13 16:28:07,220::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 16:34:57,166::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:53.015750. 2024-04-13 16:35:08,158::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45673, 45673) 2024-04-13 16:35:08,210::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 16:36:03,629::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:55.418804. 2024-04-13 16:36:06,676::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 16:42:48,037::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:44.408462. 2024-04-13 16:42:58,933::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45627, 45627) 2024-04-13 16:42:58,985::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 16:44:03,301::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:01:04.315028. 2024-04-13 16:44:06,367::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 16:50:21,779::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:18.478069. 2024-04-13 16:50:32,683::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45516, 45516) 2024-04-13 16:50:32,734::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 16:51:42,944::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:01:10.209447. 2024-04-13 16:51:46,023::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 16:58:13,729::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:30.785233. 2024-04-13 16:58:24,589::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45438, 45438) 2024-04-13 16:58:24,641::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 16:59:21,282::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:56.640766. 2024-04-13 16:59:24,340::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 17:06:13,304::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:52.021685. 2024-04-13 17:06:24,224::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45407, 45407) 2024-04-13 17:06:24,276::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 17:07:06,999::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:42.723228. 2024-04-13 17:07:10,021::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 17:14:05,328::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:58.328245. 2024-04-13 17:14:16,112::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45395, 45395) 2024-04-13 17:14:16,170::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 17:14:59,405::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:43.234331. 2024-04-13 17:15:02,419::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 17:22:25,462::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:26.056600. 2024-04-13 17:22:36,315::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45368, 45368) 2024-04-13 17:22:36,366::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 17:23:12,288::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:35.921802. 2024-04-13 17:23:15,421::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 17:30:10,864::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:58.575295. 2024-04-13 17:30:21,665::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45325, 45325) 2024-04-13 17:30:21,716::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 17:31:16,777::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:55.060395. 2024-04-13 17:31:19,819::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 17:38:10,637::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:53.859840. 2024-04-13 17:38:21,592::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45291, 45291) 2024-04-13 17:38:21,650::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 17:39:17,842::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:56.192423. 2024-04-13 17:39:20,883::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 17:46:33,455::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:15.612399. 2024-04-13 17:46:44,199::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45204, 45204) 2024-04-13 17:46:44,250::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 17:47:37,857::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:53.606066. 2024-04-13 17:47:40,910::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 17:54:35,672::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:57.814683. 2024-04-13 17:54:46,365::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45161, 45161) 2024-04-13 17:54:46,415::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 17:55:32,021::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:45.605416. 2024-04-13 17:55:35,019::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 18:02:36,587::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:04.565685. 2024-04-13 18:02:47,261::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45154, 45154) 2024-04-13 18:02:47,312::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 18:03:50,328::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:01:03.015807. 2024-04-13 18:03:53,366::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 18:10:54,966::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:04.638062. 2024-04-13 18:11:05,667::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45148, 45148) 2024-04-13 18:11:05,718::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 18:11:55,097::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:49.379123. 2024-04-13 18:11:58,148::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 18:19:10,157::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:15.059859. 2024-04-13 18:19:20,868::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45142, 45142) 2024-04-13 18:19:20,921::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 18:20:06,647::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:45.725326. 2024-04-13 18:20:09,670::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 18:26:36,297::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:29.649368. 2024-04-13 18:26:46,981::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45116, 45116) 2024-04-13 18:26:47,032::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 18:27:29,449::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:42.416826. 2024-04-13 18:27:32,447::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 18:34:23,910::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:54.460947. 2024-04-13 18:34:34,609::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45095, 45095) 2024-04-13 18:34:34,660::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 18:35:10,646::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:35.986054. 2024-04-13 18:35:13,678::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 18:42:09,275::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:58.628779. 2024-04-13 18:42:20,132::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45046, 45046) 2024-04-13 18:42:20,183::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 18:43:13,973::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:53.790390. 2024-04-13 18:43:17,041::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 18:50:15,644::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:01.670957. 2024-04-13 18:50:26,479::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (45044, 45044) 2024-04-13 18:50:26,535::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 18:51:48,911::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:01:22.375472. 2024-04-13 18:51:52,022::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 18:58:30,393::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:41.481289. 2024-04-13 18:58:41,162::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (44971, 44971) 2024-04-13 18:58:41,219::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 18:59:31,595::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:50.375574. 2024-04-13 18:59:34,646::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 19:06:21,113::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:49.517443. 2024-04-13 19:06:31,891::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (44969, 44969) 2024-04-13 19:06:31,941::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 19:07:24,999::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:53.057811. 2024-04-13 19:07:28,061::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 19:14:09,153::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:44.153629. 2024-04-13 19:14:19,794::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (44925, 44925) 2024-04-13 19:14:19,845::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 19:15:16,878::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:57.033118. 2024-04-13 19:15:19,943::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 19:22:14,023::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:57.145111. 2024-04-13 19:22:24,735::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (44922, 44922) 2024-04-13 19:22:24,792::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 19:23:14,424::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:49.631402. 2024-04-13 19:23:17,488::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 19:30:23,709::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:09.285193. 2024-04-13 19:30:34,400::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (44906, 44906) 2024-04-13 19:30:34,450::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 19:31:23,482::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:49.031155. 2024-04-13 19:31:26,524::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 19:37:57,599::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:34.116647. 2024-04-13 19:38:08,206::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (44894, 44894) 2024-04-13 19:38:08,256::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 19:39:01,700::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:53.443790. 2024-04-13 19:39:04,743::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 19:46:01,096::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:59.396008. 2024-04-13 19:46:11,854::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (44863, 44863) 2024-04-13 19:46:11,904::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 19:46:49,750::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:37.846141. 2024-04-13 19:46:52,808::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 19:53:50,432::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:00.681649. 2024-04-13 19:54:01,022::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (44863, 44863) 2024-04-13 19:54:01,071::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 19:55:09,909::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:01:08.837622. 2024-04-13 19:55:12,964::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 20:01:43,909::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:33.999351. 2024-04-13 20:01:54,595::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (44748, 44748) 2024-04-13 20:01:54,651::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 20:02:48,375::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:53.723907. 2024-04-13 20:02:51,438::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 20:09:29,642::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:41.266805. 2024-04-13 20:09:40,220::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (44746, 44746) 2024-04-13 20:09:40,270::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 20:10:30,899::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:50.628347. 2024-04-13 20:10:33,924::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 20:17:18,311::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:47.411547. 2024-04-13 20:17:28,904::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (44710, 44710) 2024-04-13 20:17:28,954::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 20:18:33,087::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:01:04.132783. 2024-04-13 20:18:36,165::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 20:25:42,538::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:09.450817. 2024-04-13 20:25:53,050::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (44680, 44680) 2024-04-13 20:25:53,106::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 20:26:57,237::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:01:04.130262. 2024-04-13 20:27:00,308::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 20:34:28,640::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:31.403465. 2024-04-13 20:34:39,348::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (44637, 44637) 2024-04-13 20:34:39,398::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 20:35:41,857::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:01:02.458712. 2024-04-13 20:35:44,938::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 20:42:25,202::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:43.344640. 2024-04-13 20:42:35,616::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (44355, 44355) 2024-04-13 20:42:35,666::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 20:43:28,608::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:52.942574. 2024-04-13 20:43:31,664::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 20:50:17,676::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:49.067167. 2024-04-13 20:50:28,108::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (44289, 44289) 2024-04-13 20:50:28,157::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 20:51:29,544::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:01:01.387335. 2024-04-13 20:51:32,623::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 20:58:34,148::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:04.603531. 2024-04-13 20:58:44,624::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (44239, 44239) 2024-04-13 20:58:44,672::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 20:59:34,498::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:49.826139. 2024-04-13 20:59:37,536::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 21:06:39,847::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:05.347920. 2024-04-13 21:06:50,206::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (44237, 44237) 2024-04-13 21:06:50,255::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 21:07:22,424::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:32.169030. 2024-04-13 21:07:25,455::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 21:14:15,294::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:52.869828. 2024-04-13 21:14:25,660::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (44106, 44106) 2024-04-13 21:14:25,708::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 21:15:12,138::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:46.429580. 2024-04-13 21:15:15,157::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 21:22:13,774::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:01.635412. 2024-04-13 21:22:24,161::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (44065, 44065) 2024-04-13 21:22:24,216::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 21:23:17,887::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:53.670974. 2024-04-13 21:23:20,911::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 21:30:23,674::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:05.786501. 2024-04-13 21:30:33,960::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (44057, 44057) 2024-04-13 21:30:34,009::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 21:31:26,572::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:52.563368. 2024-04-13 21:31:29,583::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 21:38:33,509::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:06.935986. 2024-04-13 21:38:43,863::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (44055, 44055) 2024-04-13 21:38:43,911::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 21:39:32,067::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:48.155874. 2024-04-13 21:39:35,100::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 21:46:15,119::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:43.051845. 2024-04-13 21:46:25,494::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (44047, 44047) 2024-04-13 21:46:25,548::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 21:47:07,626::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:42.077102. 2024-04-13 21:47:10,659::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 21:54:42,079::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:34.453433. 2024-04-13 21:54:52,441::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (44037, 44037) 2024-04-13 21:54:52,496::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 21:55:35,305::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:42.808839. 2024-04-13 21:55:38,367::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 22:02:46,333::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:11.027810. 2024-04-13 22:02:56,689::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (44032, 44032) 2024-04-13 22:02:56,737::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 22:03:58,773::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:01:02.035653. 2024-04-13 22:04:01,847::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 22:10:38,233::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:39.460221. 2024-04-13 22:10:48,604::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (44020, 44020) 2024-04-13 22:10:48,652::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 22:11:26,067::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:37.414890. 2024-04-13 22:11:29,074::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 22:18:59,359::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:33.291858. 2024-04-13 22:19:09,799::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43995, 43995) 2024-04-13 22:19:09,847::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 22:20:10,367::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:01:00.519884. 2024-04-13 22:20:13,447::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 22:26:52,115::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:41.746921. 2024-04-13 22:27:02,488::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43922, 43922) 2024-04-13 22:27:02,537::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 22:27:45,016::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:42.478932. 2024-04-13 22:27:48,022::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 22:34:36,173::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:51.157310. 2024-04-13 22:34:46,365::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43906, 43906) 2024-04-13 22:34:46,419::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 22:35:31,129::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:44.709754. 2024-04-13 22:35:34,183::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 22:42:38,729::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:07.599965. 2024-04-13 22:42:48,965::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43899, 43899) 2024-04-13 22:42:49,013::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 22:43:44,162::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:55.149279. 2024-04-13 22:43:47,186::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 22:50:06,940::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:22.777440. 2024-04-13 22:50:17,254::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43898, 43898) 2024-04-13 22:50:17,302::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 22:51:07,299::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:49.997024. 2024-04-13 22:51:10,339::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 22:57:34,397::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:27.097520. 2024-04-13 22:57:44,752::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43817, 43817) 2024-04-13 22:57:44,799::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 22:58:18,944::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:34.144015. 2024-04-13 22:58:22,001::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 23:04:52,591::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:33.646741. 2024-04-13 23:05:02,936::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43721, 43721) 2024-04-13 23:05:02,984::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 23:05:28,332::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:25.348209. 2024-04-13 23:05:31,439::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 23:12:43,694::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:15.361027. 2024-04-13 23:12:54,021::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43662, 43662) 2024-04-13 23:12:54,068::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 23:13:15,799::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:21.730414. 2024-04-13 23:13:18,888::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 23:20:23,971::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:08.171529. 2024-04-13 23:20:34,231::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43602, 43602) 2024-04-13 23:20:34,279::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 23:20:56,240::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:21.961417. 2024-04-13 23:20:59,324::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 23:28:20,610::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:24.369255. 2024-04-13 23:28:30,894::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43578, 43578) 2024-04-13 23:28:30,948::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 23:29:07,019::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:36.071784. 2024-04-13 23:29:10,062::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 23:36:46,117::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:39.097450. 2024-04-13 23:36:56,397::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43577, 43577) 2024-04-13 23:36:56,444::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 23:37:20,622::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:24.177661. 2024-04-13 23:37:23,728::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 23:44:37,541::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:16.919727. 2024-04-13 23:44:47,701::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43568, 43568) 2024-04-13 23:44:47,754::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 23:45:11,053::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:23.298436. 2024-04-13 23:45:14,055::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 23:52:11,263::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:00.210069. 2024-04-13 23:52:21,435::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43530, 43530) 2024-04-13 23:52:21,482::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-13 23:52:42,395::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:20.912834. 2024-04-13 23:52:45,420::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-13 23:59:56,870::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:07:14.474654. 2024-04-14 00:00:07,094::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43509, 43509) 2024-04-14 00:00:07,141::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-14 00:00:29,540::DEBUG::preprocess_matrix: Loaded contact frequency matrix with shape '(57509, 57509)' in 0:00:22.398742. 2024-04-14 00:00:32,549::DEBUG::normalized_affinity_matrix_from_trans: contact_matrix.shape: (57509, 57509) 2024-04-14 00:07:10,498::DEBUG::preprocess_matrix: Computed cis-masked, balanced, affinity matrix of shape '(57509, 57509)' in 0:06:40.957455. 2024-04-14 00:07:20,562::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 00:07:20,609::DEBUG::set_union_bad_bins: Percent bad bins: 13.954337581943696. 2024-04-14 00:07:20,609::INFO::set_union_bad_bins: Loaded union set of bad bins in: 12:00:12.472726. 2024-04-14 00:07:20,609::INFO::set_union_bad_bins: Percent of bins that are bad: 24.363143160201012. 2024-04-14 00:07:20,609::DEBUG::set_union_bad_bins: Shape of bad_bin array: (57509,). 2024-04-14 00:07:20,610::DEBUG::set_union_bad_bins: Shape of bins dataframe: (57509, 5). 2024-04-14 00:07:20,610::DEBUG::set_union_bad_bins: Saving bins to file... 2024-04-14 00:07:21,346::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'day00_ESC_pool.hg38.mapq_30.100.mcool'... 2024-04-14 00:07:21,393::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 00:08:41,093::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:19.746587. 2024-04-14 00:08:49,513::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 00:08:49,514::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'day00_ESC_pool.hg38.mapq_30.100.mcool' in 0:01:28.167523. 2024-04-14 00:08:49,514::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 00:08:50,494::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 00:11:39,174::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:49.660193 seconds. 2024-04-14 00:11:40,218::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 00:14:24,989::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:45.815062 seconds. 2024-04-14 00:14:26,030::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 00:17:10,063::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:45.073697 seconds. 2024-04-14 00:17:11,099::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 00:19:57,485::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:47.421529 seconds. 2024-04-14 00:19:58,531::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 00:22:44,737::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:47.251503 seconds. 2024-04-14 00:22:44,748::INFO::decompose_cooler_file: Finished decomposition for 'day00_ESC_pool.hg38.mapq_30.100.mcool' in 0:15:23.401626. 2024-04-14 00:22:44,795::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'day02_mesoderm_pool.hg38.mapq_30.100.mcool'... 2024-04-14 00:22:44,857::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 00:24:07,418::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:22.623070. 2024-04-14 00:25:09,716::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 00:25:09,716::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'day02_mesoderm_pool.hg38.mapq_30.100.mcool' in 0:02:24.920933. 2024-04-14 00:25:09,716::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 00:25:10,707::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 00:27:53,173::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:43.457166 seconds. 2024-04-14 00:27:54,200::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 00:30:36,120::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:42.945845 seconds. 2024-04-14 00:30:37,155::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 00:33:19,816::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:43.695994 seconds. 2024-04-14 00:33:20,856::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 00:36:06,126::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:46.309983 seconds. 2024-04-14 00:36:07,157::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 00:38:51,983::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:45.857408 seconds. 2024-04-14 00:38:51,993::INFO::decompose_cooler_file: Finished decomposition for 'day02_mesoderm_pool.hg38.mapq_30.100.mcool' in 0:16:07.198328. 2024-04-14 00:38:52,041::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'day05_cardiacMesoderm_pool.hg38.mapq_30.100.mcool'... 2024-04-14 00:38:52,071::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 00:40:14,931::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:22.890150. 2024-04-14 00:41:23,857::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 00:41:23,857::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'day05_cardiacMesoderm_pool.hg38.mapq_30.100.mcool' in 0:02:31.816335. 2024-04-14 00:41:23,858::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 00:41:24,880::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 00:44:07,329::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:43.471238 seconds. 2024-04-14 00:44:08,359::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 00:46:51,016::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:43.686879 seconds. 2024-04-14 00:46:52,135::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 00:49:35,604::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:44.588087 seconds. 2024-04-14 00:49:36,636::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 00:52:22,519::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:46.914167 seconds. 2024-04-14 00:52:23,550::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 00:55:09,949::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:47.430059 seconds. 2024-04-14 00:55:09,960::INFO::decompose_cooler_file: Finished decomposition for 'day05_cardiacMesoderm_pool.hg38.mapq_30.100.mcool' in 0:16:17.918854. 2024-04-14 00:55:10,008::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'day07_cardiacProgenitor_pool.hg38.mapq_30.100.mcool'... 2024-04-14 00:55:10,087::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 00:56:30,656::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:20.646971. 2024-04-14 00:58:18,677::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 00:58:18,677::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'day07_cardiacProgenitor_pool.hg38.mapq_30.100.mcool' in 0:03:08.668665. 2024-04-14 00:58:18,677::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 00:58:19,694::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 01:00:58,713::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:40.035800 seconds. 2024-04-14 01:00:59,755::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 01:03:38,892::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:40.178696 seconds. 2024-04-14 01:03:39,932::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 01:06:19,135::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:40.243029 seconds. 2024-04-14 01:06:20,174::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 01:09:01,343::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:42.207572 seconds. 2024-04-14 01:09:02,381::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 01:11:43,628::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:42.284789 seconds. 2024-04-14 01:11:43,638::INFO::decompose_cooler_file: Finished decomposition for 'day07_cardiacProgenitor_pool.hg38.mapq_30.100.mcool' in 0:16:33.629386. 2024-04-14 01:11:43,685::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'day15_primativeCardiomyocyte_pool.hg38.mapq_30.100.mcool'... 2024-04-14 01:11:43,746::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 01:13:02,452::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:18.767136. 2024-04-14 01:14:53,700::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 01:14:53,700::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'day15_primativeCardiomyocyte_pool.hg38.mapq_30.100.mcool' in 0:03:10.015334. 2024-04-14 01:14:53,701::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 01:14:54,717::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 01:17:33,424::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:39.723432 seconds. 2024-04-14 01:17:34,457::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 01:20:13,411::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:39.986350 seconds. 2024-04-14 01:20:14,457::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 01:22:53,745::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:40.334386 seconds. 2024-04-14 01:22:54,792::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 01:25:36,190::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:42.444419 seconds. 2024-04-14 01:25:37,238::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 01:28:18,448::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:42.257549 seconds. 2024-04-14 01:28:18,459::INFO::decompose_cooler_file: Finished decomposition for 'day15_primativeCardiomyocyte_pool.hg38.mapq_30.100.mcool' in 0:16:34.773528. 2024-04-14 01:28:18,506::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'day80_ventricularCardiomyocyte_pool.hg38.mapq_30.100.mcool'... 2024-04-14 01:28:18,534::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 01:29:38,268::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:19.762312. 2024-04-14 01:31:10,609::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 01:31:10,609::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'day80_ventricularCardiomyocyte_pool.hg38.mapq_30.100.mcool' in 0:02:52.103357. 2024-04-14 01:31:10,609::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 01:31:11,625::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 01:33:51,036::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:40.426839 seconds. 2024-04-14 01:33:52,064::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 01:36:31,368::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:40.330958 seconds. 2024-04-14 01:36:32,405::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 01:39:12,277::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:40.908845 seconds. 2024-04-14 01:39:13,308::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 01:41:55,537::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:43.260046 seconds. 2024-04-14 01:41:56,572::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 01:44:38,086::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:42.548609 seconds. 2024-04-14 01:44:38,097::INFO::decompose_cooler_file: Finished decomposition for 'day80_ventricularCardiomyocyte_pool.hg38.mapq_30.100.mcool' in 0:16:19.590800. 2024-04-14 01:44:38,144::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'DE-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool'... 2024-04-14 01:44:38,180::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 01:45:57,307::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:19.162268. 2024-04-14 01:47:42,474::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 01:47:42,475::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'DE-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool' in 0:03:04.330170. 2024-04-14 01:47:42,475::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 01:47:43,494::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 01:50:23,077::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:40.601927 seconds. 2024-04-14 01:50:24,109::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 01:53:03,779::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:40.702040 seconds. 2024-04-14 01:53:04,808::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 01:55:43,914::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:40.134924 seconds. 2024-04-14 01:55:44,948::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 01:58:27,188::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:43.273548 seconds. 2024-04-14 01:58:28,217::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 02:01:10,151::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:42.963222 seconds. 2024-04-14 02:01:10,161::INFO::decompose_cooler_file: Finished decomposition for 'DE-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool' in 0:16:32.016740. 2024-04-14 02:01:10,208::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'DE_pool.hg38.mapq_30.100.mcool'... 2024-04-14 02:01:10,254::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 02:02:22,472::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:12.263068. 2024-04-14 02:03:58,302::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 02:03:58,302::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'DE_pool.hg38.mapq_30.100.mcool' in 0:02:48.093516. 2024-04-14 02:03:58,302::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 02:03:59,320::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 02:06:38,672::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:40.369841 seconds. 2024-04-14 02:06:39,711::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 02:09:19,272::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:40.599911 seconds. 2024-04-14 02:09:20,306::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 02:12:00,005::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:40.732892 seconds. 2024-04-14 02:12:01,046::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 02:14:42,593::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:42.587862 seconds. 2024-04-14 02:14:43,628::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 02:17:25,836::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:43.242350 seconds. 2024-04-14 02:17:25,847::INFO::decompose_cooler_file: Finished decomposition for 'DE_pool.hg38.mapq_30.100.mcool' in 0:16:15.638391. 2024-04-14 02:17:25,894::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF004YZQ.mcool'... 2024-04-14 02:17:25,954::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 02:18:57,469::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:31.575086. 2024-04-14 02:20:41,581::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 02:20:41,581::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF004YZQ.mcool' in 0:03:15.687267. 2024-04-14 02:20:41,581::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 02:20:42,599::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 02:23:22,686::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:41.104149 seconds. 2024-04-14 02:23:23,717::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 02:26:04,001::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:41.314733 seconds. 2024-04-14 02:26:05,033::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 02:28:44,424::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:40.422763 seconds. 2024-04-14 02:28:45,452::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 02:31:26,912::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:42.488627 seconds. 2024-04-14 02:31:27,947::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 02:34:09,572::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:42.659403 seconds. 2024-04-14 02:34:09,582::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF004YZQ.mcool' in 0:16:43.687797. 2024-04-14 02:34:09,629::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF009ONH.mcool'... 2024-04-14 02:34:09,687::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 02:35:31,944::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:22.314752. 2024-04-14 02:37:05,085::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 02:37:05,085::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF009ONH.mcool' in 0:02:55.455989. 2024-04-14 02:37:05,085::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 02:37:06,098::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 02:39:45,265::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:40.179488 seconds. 2024-04-14 02:39:46,301::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 02:42:24,541::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:39.276277 seconds. 2024-04-14 02:42:25,571::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 02:45:03,724::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:39.182708 seconds. 2024-04-14 02:45:04,756::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 02:47:46,011::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:42.286575 seconds. 2024-04-14 02:47:47,050::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 02:50:27,716::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:41.705183 seconds. 2024-04-14 02:50:27,727::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF009ONH.mcool' in 0:16:18.098332. 2024-04-14 02:50:27,780::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF019YVI.mcool'... 2024-04-14 02:50:27,859::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 02:51:51,484::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:23.704125. 2024-04-14 02:53:13,774::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 02:53:13,774::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF019YVI.mcool' in 0:02:45.994017. 2024-04-14 02:53:13,774::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 02:53:14,790::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 02:55:52,544::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:38.769927 seconds. 2024-04-14 02:55:53,590::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 02:58:31,160::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:38.616126 seconds. 2024-04-14 02:58:32,203::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 03:01:09,584::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:38.424104 seconds. 2024-04-14 03:01:10,623::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 03:03:51,263::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:41.678332 seconds. 2024-04-14 03:03:52,308::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 03:06:32,733::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:41.469542 seconds. 2024-04-14 03:06:32,743::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF019YVI.mcool' in 0:16:04.962977. 2024-04-14 03:06:32,790::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF029UAL.mcool'... 2024-04-14 03:06:32,854::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 03:07:56,383::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:23.592479. 2024-04-14 03:09:41,642::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 03:09:41,642::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF029UAL.mcool' in 0:03:08.852189. 2024-04-14 03:09:41,642::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 03:09:42,650::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 03:12:21,504::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:39.861363 seconds. 2024-04-14 03:12:22,539::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 03:15:01,104::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:39.599525 seconds. 2024-04-14 03:15:02,148::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 03:17:40,788::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:39.683855 seconds. 2024-04-14 03:17:41,829::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 03:20:23,369::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:42.581358 seconds. 2024-04-14 03:20:24,408::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 03:23:06,031::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:42.661689 seconds. 2024-04-14 03:23:06,041::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF029UAL.mcool' in 0:16:33.250769. 2024-04-14 03:23:06,088::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF035BLF.mcool'... 2024-04-14 03:23:06,240::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 03:24:36,430::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:30.341755. 2024-04-14 03:25:57,396::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 03:25:57,397::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF035BLF.mcool' in 0:02:51.308354. 2024-04-14 03:25:57,397::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 03:25:58,420::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 03:28:37,765::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:40.368447 seconds. 2024-04-14 03:28:38,801::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 03:31:17,887::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:40.121136 seconds. 2024-04-14 03:31:18,924::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 03:33:58,604::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:40.717223 seconds. 2024-04-14 03:33:59,642::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 03:36:42,472::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:43.868167 seconds. 2024-04-14 03:36:43,491::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 03:39:26,294::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:43.821811 seconds. 2024-04-14 03:39:26,305::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF035BLF.mcool' in 0:16:20.217202. 2024-04-14 03:39:26,353::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF044TCQ.mcool'... 2024-04-14 03:39:26,391::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 03:40:45,835::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:19.482260. 2024-04-14 03:41:10,398::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 03:41:10,399::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF044TCQ.mcool' in 0:01:44.045998. 2024-04-14 03:41:10,399::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 03:41:11,381::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 03:43:50,935::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:40.535805 seconds. 2024-04-14 03:43:51,976::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 03:46:31,309::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:40.373703 seconds. 2024-04-14 03:46:32,348::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 03:49:12,150::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:40.841597 seconds. 2024-04-14 03:49:13,182::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 03:51:55,723::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:43.572302 seconds. 2024-04-14 03:51:56,709::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 03:54:39,486::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:43.763188 seconds. 2024-04-14 03:54:39,497::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF044TCQ.mcool' in 0:15:13.144657. 2024-04-14 03:54:39,545::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF059WMS.mcool'... 2024-04-14 03:54:39,595::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 03:56:02,283::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:22.738144. 2024-04-14 03:56:57,344::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 03:56:57,344::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF059WMS.mcool' in 0:02:17.799377. 2024-04-14 03:56:57,344::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 03:56:58,333::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 03:59:37,940::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:40.595315 seconds. 2024-04-14 03:59:38,980::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 04:02:18,827::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:40.887281 seconds. 2024-04-14 04:02:19,876::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 04:04:59,498::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:40.670699 seconds. 2024-04-14 04:05:00,544::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 04:07:43,416::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:43.917732 seconds. 2024-04-14 04:07:44,451::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 04:10:27,204::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:43.787659 seconds. 2024-04-14 04:10:27,214::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF059WMS.mcool' in 0:15:47.668842. 2024-04-14 04:10:27,261::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF076LWH.mcool'... 2024-04-14 04:10:27,340::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 04:11:55,704::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:28.443023. 2024-04-14 04:13:16,152::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 04:13:16,152::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF076LWH.mcool' in 0:02:48.891184. 2024-04-14 04:13:16,152::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 04:13:17,174::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 04:15:56,882::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:40.729596 seconds. 2024-04-14 04:15:57,907::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 04:18:37,372::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:40.489513 seconds. 2024-04-14 04:18:38,402::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 04:21:18,493::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:41.121540 seconds. 2024-04-14 04:21:19,521::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 04:24:02,389::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:43.895594 seconds. 2024-04-14 04:24:03,424::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 04:26:46,455::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:44.065782 seconds. 2024-04-14 04:26:46,466::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF076LWH.mcool' in 0:16:19.205356. 2024-04-14 04:26:46,514::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF081PMO.mcool'... 2024-04-14 04:26:46,602::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 04:28:13,382::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:26.868552. 2024-04-14 04:29:31,256::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 04:29:31,256::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF081PMO.mcool' in 0:02:44.742321. 2024-04-14 04:29:31,256::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 04:29:32,280::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 04:32:12,032::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:40.775231 seconds. 2024-04-14 04:32:13,061::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 04:34:52,840::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:40.808169 seconds. 2024-04-14 04:34:53,882::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 04:37:33,703::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:40.863065 seconds. 2024-04-14 04:37:34,736::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 04:40:17,507::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:43.803581 seconds. 2024-04-14 04:40:18,546::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 04:43:01,549::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:44.041859 seconds. 2024-04-14 04:43:01,560::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF081PMO.mcool' in 0:16:15.046379. 2024-04-14 04:43:01,610::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF094KKX.mcool'... 2024-04-14 04:43:01,640::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 04:44:26,949::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:25.339621. 2024-04-14 04:46:06,131::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 04:46:06,131::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF094KKX.mcool' in 0:03:04.521683. 2024-04-14 04:46:06,132::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 04:46:07,133::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 04:48:47,229::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:41.097191 seconds. 2024-04-14 04:48:48,259::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 04:51:28,559::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:41.330497 seconds. 2024-04-14 04:51:29,596::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 04:54:09,695::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:41.134931 seconds. 2024-04-14 04:54:10,734::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 04:56:53,572::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:43.877582 seconds. 2024-04-14 04:56:54,615::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 04:59:37,621::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:44.048000 seconds. 2024-04-14 04:59:37,637::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF094KKX.mcool' in 0:16:36.027440. 2024-04-14 04:59:37,691::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF136XCV.mcool'... 2024-04-14 04:59:37,759::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 05:00:59,341::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:21.649695. 2024-04-14 05:02:50,803::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 05:02:50,804::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF136XCV.mcool' in 0:03:13.112116. 2024-04-14 05:02:50,804::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 05:02:51,826::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 05:05:32,640::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:41.836475 seconds. 2024-04-14 05:05:33,674::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 05:08:14,527::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:41.886339 seconds. 2024-04-14 05:08:15,564::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 05:10:56,465::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:41.937810 seconds. 2024-04-14 05:10:57,498::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 05:13:40,869::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:44.404331 seconds. 2024-04-14 05:13:41,908::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 05:16:25,213::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:44.343590 seconds. 2024-04-14 05:16:25,224::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF136XCV.mcool' in 0:16:47.532764. 2024-04-14 05:16:25,278::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF140ROU.mcool'... 2024-04-14 05:16:25,307::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 05:17:51,730::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:26.452517. 2024-04-14 05:19:11,603::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 05:19:11,603::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF140ROU.mcool' in 0:02:46.325702. 2024-04-14 05:19:11,604::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 05:19:12,617::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 05:21:53,463::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:41.858955 seconds. 2024-04-14 05:21:54,499::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 05:24:34,934::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:41.470754 seconds. 2024-04-14 05:24:35,967::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 05:27:16,715::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:41.780895 seconds. 2024-04-14 05:27:17,749::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 05:30:01,135::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:44.420581 seconds. 2024-04-14 05:30:02,176::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 05:32:45,573::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:44.437683 seconds. 2024-04-14 05:32:45,584::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF140ROU.mcool' in 0:16:20.306707. 2024-04-14 05:32:45,638::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF149IHN.mcool'... 2024-04-14 05:32:45,672::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 05:34:05,846::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:20.207999. 2024-04-14 05:35:44,370::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 05:35:44,370::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF149IHN.mcool' in 0:02:58.732692. 2024-04-14 05:35:44,371::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 05:35:45,371::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 05:38:25,410::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:41.039014 seconds. 2024-04-14 05:38:26,431::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 05:41:06,407::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:40.997575 seconds. 2024-04-14 05:41:07,435::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 05:43:47,558::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:41.150364 seconds. 2024-04-14 05:43:48,600::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 05:46:31,546::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:43.987759 seconds. 2024-04-14 05:46:32,582::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 05:49:15,324::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:43.777964 seconds. 2024-04-14 05:49:15,335::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF149IHN.mcool' in 0:16:29.697426. 2024-04-14 05:49:15,383::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF176LIZ.mcool'... 2024-04-14 05:49:15,417::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 05:50:37,361::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:21.978324. 2024-04-14 05:52:09,377::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 05:52:09,377::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF176LIZ.mcool' in 0:02:53.993883. 2024-04-14 05:52:09,377::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 05:52:10,374::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 05:54:50,100::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:40.723455 seconds. 2024-04-14 05:54:51,099::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 05:57:30,758::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:40.657515 seconds. 2024-04-14 05:57:31,749::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 06:00:11,377::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:40.619102 seconds. 2024-04-14 06:00:12,360::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 06:02:55,324::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:43.946567 seconds. 2024-04-14 06:02:56,323::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 06:05:39,020::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:43.695551 seconds. 2024-04-14 06:05:39,031::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF176LIZ.mcool' in 0:16:23.648152. 2024-04-14 06:05:39,078::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF185AYZ.mcool'... 2024-04-14 06:05:39,110::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 06:06:59,776::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:20.697358. 2024-04-14 06:08:41,691::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 06:08:41,691::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF185AYZ.mcool' in 0:03:02.612531. 2024-04-14 06:08:41,691::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 06:08:42,712::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 06:11:22,710::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:41.018617 seconds. 2024-04-14 06:11:23,738::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 06:14:03,730::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:41.019688 seconds. 2024-04-14 06:14:04,763::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 06:16:44,999::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:41.268863 seconds. 2024-04-14 06:16:46,020::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 06:19:28,782::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:43.783034 seconds. 2024-04-14 06:19:29,828::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 06:22:12,621::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:43.838843 seconds. 2024-04-14 06:22:12,632::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF185AYZ.mcool' in 0:16:33.553725. 2024-04-14 06:22:12,680::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF193CQL.mcool'... 2024-04-14 06:22:12,714::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 06:23:38,136::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:25.456425. 2024-04-14 06:24:49,620::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 06:24:49,620::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF193CQL.mcool' in 0:02:36.940559. 2024-04-14 06:24:49,620::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 06:24:50,637::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 06:27:30,405::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:40.783964 seconds. 2024-04-14 06:27:31,448::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 06:30:11,262::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:40.856822 seconds. 2024-04-14 06:30:12,293::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 06:32:51,858::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:40.596271 seconds. 2024-04-14 06:32:52,896::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 06:35:35,076::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:43.217903 seconds. 2024-04-14 06:35:36,116::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 06:38:18,673::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:43.596427 seconds. 2024-04-14 06:38:18,684::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF193CQL.mcool' in 0:16:06.004127. 2024-04-14 06:38:18,731::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF197OWW.mcool'... 2024-04-14 06:38:18,770::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 06:39:42,716::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:23.984546. 2024-04-14 06:41:18,553::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 06:41:18,553::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF197OWW.mcool' in 0:02:59.821413. 2024-04-14 06:41:18,553::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 06:41:19,563::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 06:43:59,565::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:41.012212 seconds. 2024-04-14 06:44:00,589::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 06:46:40,688::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:41.122290 seconds. 2024-04-14 06:46:41,712::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 06:49:21,779::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:41.091239 seconds. 2024-04-14 06:49:22,820::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 06:52:05,530::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:43.750589 seconds. 2024-04-14 06:52:06,557::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 06:54:49,290::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:43.759866 seconds. 2024-04-14 06:54:49,301::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF197OWW.mcool' in 0:16:30.569843. 2024-04-14 06:54:49,349::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF224HKR.mcool'... 2024-04-14 06:54:49,407::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 06:56:11,117::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:21.767346. 2024-04-14 06:57:42,564::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 06:57:42,564::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF224HKR.mcool' in 0:02:53.215287. 2024-04-14 06:57:42,565::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 06:57:43,569::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 07:00:23,817::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:41.252287 seconds. 2024-04-14 07:00:24,841::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 07:03:04,708::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:40.890728 seconds. 2024-04-14 07:03:05,744::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 07:05:45,911::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:41.202926 seconds. 2024-04-14 07:05:46,924::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 07:08:29,721::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:43.810299 seconds. 2024-04-14 07:08:30,758::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 07:11:13,557::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:43.834915 seconds. 2024-04-14 07:11:13,568::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF224HKR.mcool' in 0:16:24.218571. 2024-04-14 07:11:13,615::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF235LCO.mcool'... 2024-04-14 07:11:13,684::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 07:12:36,579::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:22.964088. 2024-04-14 07:13:34,462::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 07:13:34,462::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF235LCO.mcool' in 0:02:20.846560. 2024-04-14 07:13:34,462::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 07:13:35,465::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 07:16:13,507::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:39.045025 seconds. 2024-04-14 07:16:14,528::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 07:18:52,927::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:39.419267 seconds. 2024-04-14 07:18:53,973::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 07:21:31,616::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:38.689739 seconds. 2024-04-14 07:21:32,662::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 07:24:13,094::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:41.477476 seconds. 2024-04-14 07:24:14,142::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 07:26:54,697::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:41.603175 seconds. 2024-04-14 07:26:54,707::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF235LCO.mcool' in 0:15:41.092119. 2024-04-14 07:26:54,755::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF251VFA.mcool'... 2024-04-14 07:26:54,819::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 07:28:20,081::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:25.326548. 2024-04-14 07:28:54,012::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 07:28:54,012::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF251VFA.mcool' in 0:01:59.257182. 2024-04-14 07:28:54,012::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 07:28:55,034::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 07:31:32,645::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:38.633016 seconds. 2024-04-14 07:31:33,681::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 07:34:11,612::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:38.966307 seconds. 2024-04-14 07:34:12,638::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 07:36:50,359::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:38.747557 seconds. 2024-04-14 07:36:51,398::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 07:39:32,396::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:42.036179 seconds. 2024-04-14 07:39:33,437::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 07:42:13,677::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:41.280694 seconds. 2024-04-14 07:42:13,687::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF251VFA.mcool' in 0:15:18.931977. 2024-04-14 07:42:13,735::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF252ANV.mcool'... 2024-04-14 07:42:13,821::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 07:43:47,951::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:34.215451. 2024-04-14 07:44:32,851::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 07:44:32,851::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF252ANV.mcool' in 0:02:19.115954. 2024-04-14 07:44:32,852::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 07:44:33,874::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 07:47:11,909::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:39.057092 seconds. 2024-04-14 07:47:12,944::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 07:49:50,603::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:38.693915 seconds. 2024-04-14 07:49:51,641::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 07:52:29,414::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:38.811318 seconds. 2024-04-14 07:52:30,444::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 07:55:11,003::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:41.588875 seconds. 2024-04-14 07:55:12,045::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 07:57:53,122::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:42.118844 seconds. 2024-04-14 07:57:53,132::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF252ANV.mcool' in 0:15:39.396918. 2024-04-14 07:57:53,180::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF273XBU.mcool'... 2024-04-14 07:57:53,249::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 07:59:24,350::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:31.170098. 2024-04-14 08:01:09,598::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 08:01:09,598::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF273XBU.mcool' in 0:03:16.418221. 2024-04-14 08:01:09,599::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 08:01:10,608::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 08:03:47,907::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:38.308308 seconds. 2024-04-14 08:03:48,952::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 08:06:26,536::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:38.628362 seconds. 2024-04-14 08:06:27,579::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 08:09:05,118::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:38.582648 seconds. 2024-04-14 08:09:06,154::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 08:11:46,568::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:41.449286 seconds. 2024-04-14 08:11:47,603::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 08:14:31,198::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:44.630216 seconds. 2024-04-14 08:14:31,208::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF273XBU.mcool' in 0:16:38.027958. 2024-04-14 08:14:31,261::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF284OEA.mcool'... 2024-04-14 08:14:31,343::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 08:15:57,686::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:26.424298. 2024-04-14 08:17:04,270::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 08:17:04,270::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF284OEA.mcool' in 0:02:33.008896. 2024-04-14 08:17:04,271::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 08:17:05,269::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 08:19:46,057::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:41.786414 seconds. 2024-04-14 08:19:47,091::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 08:22:27,555::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:41.497757 seconds. 2024-04-14 08:22:28,590::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 08:25:09,044::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:41.488390 seconds. 2024-04-14 08:25:10,079::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 08:27:54,032::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:44.988610 seconds. 2024-04-14 08:27:55,058::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 08:30:38,964::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:44.931729 seconds. 2024-04-14 08:30:38,975::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF284OEA.mcool' in 0:16:07.713830. 2024-04-14 08:30:39,023::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF309UNV.mcool'... 2024-04-14 08:30:39,090::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 08:32:05,800::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:26.777101. 2024-04-14 08:34:09,523::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 08:34:09,523::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF309UNV.mcool' in 0:03:30.500625. 2024-04-14 08:34:09,524::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 08:34:10,539::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 08:36:52,014::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:42.490728 seconds. 2024-04-14 08:36:53,058::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 08:39:34,378::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:42.363540 seconds. 2024-04-14 08:39:35,409::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 08:42:16,528::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:42.150090 seconds. 2024-04-14 08:42:17,557::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 08:45:01,456::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:44.927167 seconds. 2024-04-14 08:45:02,484::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 08:47:46,306::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:44.850301 seconds. 2024-04-14 08:47:46,317::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF309UNV.mcool' in 0:17:07.294543. 2024-04-14 08:47:46,371::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF333WCK.mcool'... 2024-04-14 08:47:46,471::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 08:49:15,836::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:29.465568. 2024-04-14 08:50:53,951::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 08:50:53,952::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF333WCK.mcool' in 0:03:07.580882. 2024-04-14 08:50:53,952::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 08:50:54,968::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 08:53:36,198::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:42.246571 seconds. 2024-04-14 08:53:37,226::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 08:56:18,439::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:42.240168 seconds. 2024-04-14 08:56:19,465::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 08:59:00,225::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:41.786561 seconds. 2024-04-14 08:59:01,259::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 09:01:45,255::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:45.029784 seconds. 2024-04-14 09:01:46,301::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 09:04:30,505::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:45.249686 seconds. 2024-04-14 09:04:30,516::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF333WCK.mcool' in 0:16:44.145735. 2024-04-14 09:04:30,570::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF355NFJ.mcool'... 2024-04-14 09:04:30,637::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 09:05:55,272::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:24.702521. 2024-04-14 09:07:12,975::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 09:07:12,975::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF355NFJ.mcool' in 0:02:42.405289. 2024-04-14 09:07:12,975::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 09:07:13,976::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 09:09:54,863::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:41.887375 seconds. 2024-04-14 09:09:55,899::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 09:12:37,314::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:42.451165 seconds. 2024-04-14 09:12:38,353::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 09:15:19,172::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:41.858321 seconds. 2024-04-14 09:15:20,206::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 09:18:03,947::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:44.774260 seconds. 2024-04-14 09:18:04,984::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 09:20:49,028::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:45.080964 seconds. 2024-04-14 09:20:49,038::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF355NFJ.mcool' in 0:16:18.468212. 2024-04-14 09:20:49,085::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF355VJW.mcool'... 2024-04-14 09:20:49,153::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 09:22:15,686::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:26.600729. 2024-04-14 09:23:45,706::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 09:23:45,707::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF355VJW.mcool' in 0:02:56.621417. 2024-04-14 09:23:45,707::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 09:23:46,724::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 09:26:27,709::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:42.002629 seconds. 2024-04-14 09:26:28,748::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 09:29:10,145::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:42.435457 seconds. 2024-04-14 09:29:11,186::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 09:31:52,414::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:42.268984 seconds. 2024-04-14 09:31:53,451::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 09:34:37,408::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:44.993543 seconds. 2024-04-14 09:34:38,444::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 09:37:22,608::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:45.199470 seconds. 2024-04-14 09:37:22,619::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF355VJW.mcool' in 0:16:33.533984. 2024-04-14 09:37:22,673::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF395INO.mcool'... 2024-04-14 09:37:22,755::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 09:38:51,114::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:28.440642. 2024-04-14 09:40:18,015::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 09:40:18,015::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF395INO.mcool' in 0:02:55.342524. 2024-04-14 09:40:18,016::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 09:40:19,035::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 09:42:58,325::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:40.309035 seconds. 2024-04-14 09:42:59,343::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 09:45:38,314::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:39.988663 seconds. 2024-04-14 09:45:39,343::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 09:48:18,225::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:39.911082 seconds. 2024-04-14 09:48:19,246::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 09:51:01,288::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:43.062770 seconds. 2024-04-14 09:51:02,325::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 09:53:44,070::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:42.782022 seconds. 2024-04-14 09:53:44,080::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF395INO.mcool' in 0:16:21.406985. 2024-04-14 09:53:44,133::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF417GBZ.mcool'... 2024-04-14 09:53:44,199::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 09:55:08,374::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:24.241342. 2024-04-14 09:57:03,751::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 09:57:03,751::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF417GBZ.mcool' in 0:03:19.617761. 2024-04-14 09:57:03,751::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 09:57:04,736::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 09:59:43,878::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:40.126892 seconds. 2024-04-14 09:59:44,908::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 10:02:25,056::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:41.177856 seconds. 2024-04-14 10:02:26,084::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 10:05:05,893::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:40.837137 seconds. 2024-04-14 10:05:06,909::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 10:07:49,514::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:43.620849 seconds. 2024-04-14 10:07:50,546::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 10:10:32,757::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:43.242868 seconds. 2024-04-14 10:10:32,767::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF417GBZ.mcool' in 0:16:48.634253. 2024-04-14 10:10:32,815::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF442IGJ.mcool'... 2024-04-14 10:10:32,867::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 10:11:53,372::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:20.556899. 2024-04-14 10:12:53,139::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 10:12:53,139::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF442IGJ.mcool' in 0:02:20.324179. 2024-04-14 10:12:53,139::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 10:12:54,172::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 10:15:34,148::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:41.008457 seconds. 2024-04-14 10:15:35,174::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 10:18:14,977::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:40.829516 seconds. 2024-04-14 10:18:16,012::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 10:21:00,231::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:45.253513 seconds. 2024-04-14 10:21:01,271::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 10:23:48,211::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:47.979631 seconds. 2024-04-14 10:23:49,246::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 10:26:35,793::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:47.582251 seconds. 2024-04-14 10:26:35,803::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF442IGJ.mcool' in 0:16:02.988422. 2024-04-14 10:26:35,850::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF458VBB.mcool'... 2024-04-14 10:26:35,910::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 10:27:57,223::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:21.372052. 2024-04-14 10:30:06,598::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 10:30:06,598::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF458VBB.mcool' in 0:03:30.747336. 2024-04-14 10:30:06,598::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 10:30:07,612::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 10:32:52,063::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:45.464627 seconds. 2024-04-14 10:32:53,111::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 10:35:37,390::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:45.327344 seconds. 2024-04-14 10:35:38,434::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 10:38:22,652::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:45.261714 seconds. 2024-04-14 10:38:23,697::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 10:41:10,438::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:47.785507 seconds. 2024-04-14 10:41:11,472::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 10:43:58,257::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:47.819432 seconds. 2024-04-14 10:43:58,269::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF458VBB.mcool' in 0:17:22.417961. 2024-04-14 10:43:58,322::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF493SFI.mcool'... 2024-04-14 10:43:58,372::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 10:45:17,464::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:19.142284. 2024-04-14 10:46:31,796::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 10:46:31,796::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF493SFI.mcool' in 0:02:33.474336. 2024-04-14 10:46:31,796::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 10:46:32,815::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 10:49:17,041::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:45.244354 seconds. 2024-04-14 10:49:18,084::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 10:52:01,963::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:44.921933 seconds. 2024-04-14 10:52:02,999::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 10:54:47,019::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:45.055508 seconds. 2024-04-14 10:54:48,061::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 10:57:34,544::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:47.525174 seconds. 2024-04-14 10:57:35,583::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 11:00:22,201::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:47.656830 seconds. 2024-04-14 11:00:22,211::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF493SFI.mcool' in 0:16:23.888950. 2024-04-14 11:00:22,258::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF493YNC.mcool'... 2024-04-14 11:00:22,319::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 11:01:46,746::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:24.487633. 2024-04-14 11:02:36,567::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 11:02:36,567::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF493YNC.mcool' in 0:02:14.308845. 2024-04-14 11:02:36,567::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 11:02:37,581::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 11:05:21,701::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:45.133664 seconds. 2024-04-14 11:05:22,741::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 11:08:07,514::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:45.812912 seconds. 2024-04-14 11:08:08,554::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 11:10:53,367::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:45.853184 seconds. 2024-04-14 11:10:54,405::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 11:13:41,040::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:47.672549 seconds. 2024-04-14 11:13:42,080::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 11:16:28,835::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:47.794948 seconds. 2024-04-14 11:16:28,846::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF493YNC.mcool' in 0:16:06.588003. 2024-04-14 11:16:28,893::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF496GEU.mcool'... 2024-04-14 11:16:28,954::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 11:17:52,304::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:23.411404. 2024-04-14 11:18:53,614::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 11:18:53,614::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF496GEU.mcool' in 0:02:24.721582. 2024-04-14 11:18:53,614::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 11:18:54,627::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 11:21:38,538::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:44.923446 seconds. 2024-04-14 11:21:39,578::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 11:24:23,345::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:44.806811 seconds. 2024-04-14 11:24:24,387::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 11:27:08,831::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:45.485655 seconds. 2024-04-14 11:27:09,871::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 11:29:56,345::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:47.514329 seconds. 2024-04-14 11:29:57,385::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 11:32:44,127::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:47.781037 seconds. 2024-04-14 11:32:44,138::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF496GEU.mcool' in 0:16:15.244813. 2024-04-14 11:32:44,185::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF499BVX.mcool'... 2024-04-14 11:32:44,264::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 11:34:08,282::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:24.097540. 2024-04-14 11:34:51,306::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 11:34:51,306::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF499BVX.mcool' in 0:02:07.120954. 2024-04-14 11:34:51,306::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 11:34:52,325::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 11:37:36,322::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:45.016050 seconds. 2024-04-14 11:37:37,353::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 11:40:21,743::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:45.420628 seconds. 2024-04-14 11:40:22,791::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 11:43:07,163::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:45.419760 seconds. 2024-04-14 11:43:08,203::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 11:45:54,837::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:47.673591 seconds. 2024-04-14 11:45:55,870::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 11:48:42,876::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:48.039157 seconds. 2024-04-14 11:48:42,887::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF499BVX.mcool' in 0:15:58.702167. 2024-04-14 11:48:42,934::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF515ZBF.mcool'... 2024-04-14 11:48:43,015::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 11:50:07,381::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:24.447118. 2024-04-14 11:51:29,007::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 11:51:29,007::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF515ZBF.mcool' in 0:02:46.073312. 2024-04-14 11:51:29,008::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 11:51:30,011::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 11:54:13,896::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:44.888149 seconds. 2024-04-14 11:54:14,939::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 11:56:58,845::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:44.949100 seconds. 2024-04-14 11:56:59,879::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 11:59:43,796::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:44.950866 seconds. 2024-04-14 11:59:44,836::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 12:02:31,543::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:47.746748 seconds. 2024-04-14 12:02:32,578::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 12:05:19,206::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:47.662319 seconds. 2024-04-14 12:05:19,217::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF515ZBF.mcool' in 0:16:36.282655. 2024-04-14 12:05:19,264::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF520GFL.mcool'... 2024-04-14 12:05:19,338::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 12:06:46,182::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:26.917422. 2024-04-14 12:08:04,428::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 12:08:04,428::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF520GFL.mcool' in 0:02:45.163880. 2024-04-14 12:08:04,428::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 12:08:05,440::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 12:10:48,361::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:43.932467 seconds. 2024-04-14 12:10:49,399::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 12:13:32,722::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:44.360881 seconds. 2024-04-14 12:13:33,735::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 12:16:17,485::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:44.762969 seconds. 2024-04-14 12:16:18,512::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 12:19:03,898::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:46.413016 seconds. 2024-04-14 12:19:04,907::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 12:21:49,660::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:45.761442 seconds. 2024-04-14 12:21:49,671::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF520GFL.mcool' in 0:16:30.406798. 2024-04-14 12:21:49,722::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF545GBW.mcool'... 2024-04-14 12:21:49,783::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 12:23:11,784::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:22.061890. 2024-04-14 12:25:07,848::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 12:25:07,848::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF545GBW.mcool' in 0:03:18.125557. 2024-04-14 12:25:07,848::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 12:25:08,862::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 12:27:49,901::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:42.052628 seconds. 2024-04-14 12:27:50,935::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 12:30:32,486::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:42.585276 seconds. 2024-04-14 12:30:33,527::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 12:33:14,493::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:42.007021 seconds. 2024-04-14 12:33:15,489::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 12:35:59,284::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:44.789926 seconds. 2024-04-14 12:36:00,284::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 12:38:44,307::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:45.022971 seconds. 2024-04-14 12:38:44,318::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF545GBW.mcool' in 0:16:54.595451. 2024-04-14 12:38:44,365::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF556RLR.mcool'... 2024-04-14 12:38:44,429::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 12:40:06,192::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:21.826439. 2024-04-14 12:41:43,354::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 12:41:43,355::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF556RLR.mcool' in 0:02:58.989044. 2024-04-14 12:41:43,355::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 12:41:44,337::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 12:44:25,292::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:41.936933 seconds. 2024-04-14 12:44:26,329::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 12:47:07,147::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:41.855190 seconds. 2024-04-14 12:47:08,184::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 12:49:49,381::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:42.233551 seconds. 2024-04-14 12:49:50,507::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 12:52:35,042::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:45.661150 seconds. 2024-04-14 12:52:36,073::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 12:55:19,667::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:44.624475 seconds. 2024-04-14 12:55:19,677::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF556RLR.mcool' in 0:16:35.311333. 2024-04-14 12:55:19,724::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF558DYU.mcool'... 2024-04-14 12:55:19,791::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 12:56:41,159::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:21.434238. 2024-04-14 12:57:54,716::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 12:57:54,716::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF558DYU.mcool' in 0:02:34.991974. 2024-04-14 12:57:54,717::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 12:57:55,732::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 13:00:31,923::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:37.206169 seconds. 2024-04-14 13:00:32,955::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 13:03:08,602::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:36.678964 seconds. 2024-04-14 13:03:09,650::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 13:05:45,355::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:36.752948 seconds. 2024-04-14 13:05:46,393::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 13:08:24,850::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:39.494623 seconds. 2024-04-14 13:08:25,887::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 13:11:04,220::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:39.370218 seconds. 2024-04-14 13:11:04,231::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF558DYU.mcool' in 0:15:44.506956. 2024-04-14 13:11:04,279::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF571GTF.mcool'... 2024-04-14 13:11:04,334::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 13:12:25,245::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:20.965990. 2024-04-14 13:13:58,183::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 13:13:58,183::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF571GTF.mcool' in 0:02:53.904354. 2024-04-14 13:13:58,183::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 13:13:59,198::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 13:16:34,964::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:36.780177 seconds. 2024-04-14 13:16:36,004::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 13:19:11,979::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:37.015365 seconds. 2024-04-14 13:19:13,017::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 13:21:49,165::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:37.185856 seconds. 2024-04-14 13:21:50,205::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 13:24:28,928::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:39.762108 seconds. 2024-04-14 13:24:29,974::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 13:27:08,503::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:39.575412 seconds. 2024-04-14 13:27:08,514::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF571GTF.mcool' in 0:16:04.235442. 2024-04-14 13:27:08,568::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF579CAR.mcool'... 2024-04-14 13:27:08,632::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 13:28:33,821::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:25.253367. 2024-04-14 13:29:57,669::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 13:29:57,669::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF579CAR.mcool' in 0:02:49.101565. 2024-04-14 13:29:57,670::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 13:29:58,685::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 13:32:34,637::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:36.967444 seconds. 2024-04-14 13:32:35,680::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 13:35:11,806::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:37.168518 seconds. 2024-04-14 13:35:12,842::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 13:37:48,700::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:36.894116 seconds. 2024-04-14 13:37:49,769::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 13:40:28,131::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:39.431151 seconds. 2024-04-14 13:40:29,166::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 13:43:07,942::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:39.810290 seconds. 2024-04-14 13:43:07,953::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF579CAR.mcool' in 0:15:59.385202. 2024-04-14 13:43:08,006::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF586MQY.mcool'... 2024-04-14 13:43:08,080::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 13:44:33,498::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:25.491137. 2024-04-14 13:46:08,783::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 13:46:08,784::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF586MQY.mcool' in 0:03:00.777086. 2024-04-14 13:46:08,784::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 13:46:09,795::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 13:48:46,045::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:37.261562 seconds. 2024-04-14 13:48:47,085::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 13:51:23,433::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:37.386947 seconds. 2024-04-14 13:51:24,466::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 13:54:00,669::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:37.236436 seconds. 2024-04-14 13:54:01,711::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 13:56:40,723::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:40.054068 seconds. 2024-04-14 13:56:41,765::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 13:59:20,574::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:39.850577 seconds. 2024-04-14 13:59:20,584::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF586MQY.mcool' in 0:16:12.577670. 2024-04-14 13:59:20,632::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF591MHA.mcool'... 2024-04-14 13:59:20,691::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 14:00:42,359::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:21.727084. 2024-04-14 14:01:27,623::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 14:01:27,623::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF591MHA.mcool' in 0:02:06.991262. 2024-04-14 14:01:27,623::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 14:01:28,637::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 14:04:04,574::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:36.950742 seconds. 2024-04-14 14:04:05,610::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 14:06:41,389::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:36.815025 seconds. 2024-04-14 14:06:42,431::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 14:09:18,452::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:37.062362 seconds. 2024-04-14 14:09:19,486::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 14:11:58,492::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:40.039791 seconds. 2024-04-14 14:11:59,531::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 14:14:38,170::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:39.677933 seconds. 2024-04-14 14:14:38,181::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF591MHA.mcool' in 0:15:17.549198. 2024-04-14 14:14:38,228::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF605CEN.mcool'... 2024-04-14 14:14:38,293::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 14:16:06,193::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:27.964669. 2024-04-14 14:17:38,694::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 14:17:38,694::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF605CEN.mcool' in 0:03:00.465591. 2024-04-14 14:17:38,694::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 14:17:39,711::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 14:20:16,328::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:37.633892 seconds. 2024-04-14 14:20:17,368::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 14:22:53,533::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:37.205043 seconds. 2024-04-14 14:22:54,546::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 14:25:31,100::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:37.566754 seconds. 2024-04-14 14:25:32,113::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 14:28:35,501::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:03:04.400234 seconds. 2024-04-14 14:28:36,531::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 14:31:18,665::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:43.163676 seconds. 2024-04-14 14:31:18,674::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF605CEN.mcool' in 0:16:40.445950. 2024-04-14 14:31:18,721::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF614IPZ.mcool'... 2024-04-14 14:31:18,779::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 14:33:23,202::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:02:04.480062. 2024-04-14 14:34:19,579::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 14:34:19,579::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF614IPZ.mcool' in 0:03:00.857406. 2024-04-14 14:34:19,579::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 14:34:20,590::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 14:36:59,658::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:40.078970 seconds. 2024-04-14 14:37:00,683::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 14:39:39,637::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:39.978976 seconds. 2024-04-14 14:39:40,660::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 14:42:30,852::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:51.214540 seconds. 2024-04-14 14:42:31,890::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 14:45:13,872::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:43.020087 seconds. 2024-04-14 14:45:14,913::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 14:47:56,101::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:42.228562 seconds. 2024-04-14 14:47:56,112::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF614IPZ.mcool' in 0:16:37.390561. 2024-04-14 14:47:56,159::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF625VNK.mcool'... 2024-04-14 14:47:56,216::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 14:49:40,989::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:44.829910. 2024-04-14 14:50:59,356::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 14:50:59,356::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF625VNK.mcool' in 0:03:03.196802. 2024-04-14 14:50:59,356::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 14:51:00,360::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 14:53:38,778::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:39.421459 seconds. 2024-04-14 14:53:39,806::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 14:56:18,461::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:39.682754 seconds. 2024-04-14 14:56:19,490::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 14:58:58,290::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:39.829348 seconds. 2024-04-14 14:58:59,317::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 15:01:40,414::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:42.123490 seconds. 2024-04-14 15:01:41,463::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 15:04:19,457::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:39.043018 seconds. 2024-04-14 15:04:19,467::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF625VNK.mcool' in 0:16:23.307682. 2024-04-14 15:04:19,520::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF628LQQ.mcool'... 2024-04-14 15:04:19,576::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 15:05:41,452::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:21.931852. 2024-04-14 15:06:24,286::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 15:06:24,286::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF628LQQ.mcool' in 0:02:04.765871. 2024-04-14 15:06:24,286::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 15:06:25,305::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 15:09:01,355::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:37.068791 seconds. 2024-04-14 15:09:02,402::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 15:11:38,449::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:37.093798 seconds. 2024-04-14 15:11:39,500::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 15:14:15,493::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:37.043547 seconds. 2024-04-14 15:14:16,541::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 15:16:54,551::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:39.057611 seconds. 2024-04-14 15:16:55,592::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 15:19:33,531::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:38.980277 seconds. 2024-04-14 15:19:33,541::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF628LQQ.mcool' in 0:15:14.020827. 2024-04-14 15:19:33,589::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF653HCO.mcool'... 2024-04-14 15:19:33,657::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 15:20:59,184::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:25.594620. 2024-04-14 15:23:02,141::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 15:23:02,141::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF653HCO.mcool' in 0:03:28.552331. 2024-04-14 15:23:02,141::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 15:23:03,157::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 15:25:39,196::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:37.054225 seconds. 2024-04-14 15:25:40,239::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 15:28:16,325::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:37.128955 seconds. 2024-04-14 15:28:17,371::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 15:30:53,115::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:36.790011 seconds. 2024-04-14 15:30:54,155::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 15:33:32,889::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:39.773298 seconds. 2024-04-14 15:33:33,921::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 15:36:12,271::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:39.381792 seconds. 2024-04-14 15:36:12,282::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF653HCO.mcool' in 0:16:38.692651. 2024-04-14 15:36:12,335::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF654YIQ.mcool'... 2024-04-14 15:36:12,385::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 15:37:32,736::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:20.401417. 2024-04-14 15:38:51,705::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 15:38:51,705::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF654YIQ.mcool' in 0:02:39.369924. 2024-04-14 15:38:51,705::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 15:38:52,721::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 15:41:28,678::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:36.973005 seconds. 2024-04-14 15:41:29,712::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 15:44:05,444::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:36.766145 seconds. 2024-04-14 15:44:06,490::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 15:46:42,159::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:36.714697 seconds. 2024-04-14 15:46:43,207::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 15:49:21,876::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:39.716931 seconds. 2024-04-14 15:49:22,910::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 15:52:01,524::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:39.647507 seconds. 2024-04-14 15:52:01,534::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF654YIQ.mcool' in 0:15:49.199105. 2024-04-14 15:52:01,581::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF660JWA.mcool'... 2024-04-14 15:52:01,652::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 15:53:27,956::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:26.375169. 2024-04-14 15:54:53,980::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 15:54:53,980::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF660JWA.mcool' in 0:02:52.398536. 2024-04-14 15:54:53,980::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 15:54:54,999::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 15:57:31,239::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:37.258938 seconds. 2024-04-14 15:57:32,277::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 16:00:08,399::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:37.159544 seconds. 2024-04-14 16:00:09,440::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 16:02:45,476::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:37.077500 seconds. 2024-04-14 16:02:46,521::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 16:05:25,535::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:40.058864 seconds. 2024-04-14 16:05:26,572::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 16:08:05,306::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:39.770024 seconds. 2024-04-14 16:08:05,317::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF660JWA.mcool' in 0:16:03.735425. 2024-04-14 16:08:05,370::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF663FRL.mcool'... 2024-04-14 16:08:05,437::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 16:09:30,598::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:25.228136. 2024-04-14 16:11:06,013::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 16:11:06,013::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF663FRL.mcool' in 0:03:00.642677. 2024-04-14 16:11:06,013::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 16:11:07,028::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 16:13:43,323::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:37.310409 seconds. 2024-04-14 16:13:44,370::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 16:16:20,582::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:37.258505 seconds. 2024-04-14 16:16:21,628::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 16:18:57,799::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:37.216640 seconds. 2024-04-14 16:18:58,841::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 16:21:37,520::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:39.720522 seconds. 2024-04-14 16:21:38,562::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 16:24:16,998::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:39.478197 seconds. 2024-04-14 16:24:17,009::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF663FRL.mcool' in 0:16:11.639018. 2024-04-14 16:24:17,062::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF684YCT.mcool'... 2024-04-14 16:24:17,127::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 16:25:39,120::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:22.057698. 2024-04-14 16:27:04,112::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 16:27:04,112::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF684YCT.mcool' in 0:02:47.049674. 2024-04-14 16:27:04,112::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 16:27:05,129::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 16:29:41,518::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:37.405268 seconds. 2024-04-14 16:29:42,563::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 16:32:19,003::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:37.485616 seconds. 2024-04-14 16:32:20,044::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 16:34:56,712::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:37.708802 seconds. 2024-04-14 16:34:57,758::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 16:37:36,760::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:40.047160 seconds. 2024-04-14 16:37:37,803::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 16:40:19,044::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:42.283742 seconds. 2024-04-14 16:40:19,054::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF684YCT.mcool' in 0:16:01.991059. 2024-04-14 16:40:19,101::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF687ATD.mcool'... 2024-04-14 16:40:19,168::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 16:41:48,447::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:29.345702. 2024-04-14 16:43:00,787::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 16:43:00,787::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF687ATD.mcool' in 0:02:41.686166. 2024-04-14 16:43:00,787::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 16:43:01,804::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 16:45:40,721::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:39.933608 seconds. 2024-04-14 16:45:41,760::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 16:48:20,372::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:39.651363 seconds. 2024-04-14 16:48:21,412::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 16:51:00,058::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:39.685686 seconds. 2024-04-14 16:51:01,086::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 16:53:42,648::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:42.589216 seconds. 2024-04-14 16:53:43,690::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 16:56:25,100::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:42.452190 seconds. 2024-04-14 16:56:25,111::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF687ATD.mcool' in 0:16:06.010332. 2024-04-14 16:56:25,158::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF700CYI.mcool'... 2024-04-14 16:56:25,230::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 16:57:50,457::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:25.298420. 2024-04-14 16:59:06,929::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 16:59:06,929::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF700CYI.mcool' in 0:02:41.770408. 2024-04-14 16:59:06,929::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 16:59:07,946::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 17:01:47,500::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:40.570966 seconds. 2024-04-14 17:01:48,536::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 17:04:27,444::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:39.943763 seconds. 2024-04-14 17:04:28,476::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 17:07:07,578::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:40.134038 seconds. 2024-04-14 17:07:08,617::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 17:09:50,311::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:42.732886 seconds. 2024-04-14 17:09:51,339::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 17:12:32,964::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:42.652581 seconds. 2024-04-14 17:12:32,975::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF700CYI.mcool' in 0:16:07.816847. 2024-04-14 17:12:33,023::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF705YZH.mcool'... 2024-04-14 17:12:33,088::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 17:14:00,785::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:27.762035. 2024-04-14 17:14:41,073::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 17:14:41,073::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF705YZH.mcool' in 0:02:08.050202. 2024-04-14 17:14:41,074::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 17:14:42,076::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 17:17:22,733::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:41.659187 seconds. 2024-04-14 17:17:23,767::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 17:20:04,394::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:41.660604 seconds. 2024-04-14 17:20:05,410::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 17:22:46,799::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:42.404894 seconds. 2024-04-14 17:22:47,831::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 17:25:30,243::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:43.443690 seconds. 2024-04-14 17:25:31,272::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 17:28:13,585::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:43.342515 seconds. 2024-04-14 17:28:13,597::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF705YZH.mcool' in 0:15:40.573294. 2024-04-14 17:28:13,651::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF711XSR.mcool'... 2024-04-14 17:28:13,716::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 17:29:45,638::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:31.987693. 2024-04-14 17:30:31,870::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 17:30:31,871::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF711XSR.mcool' in 0:02:18.219905. 2024-04-14 17:30:31,871::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 17:30:32,880::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 17:33:13,702::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:41.830812 seconds. 2024-04-14 17:33:14,737::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 17:35:55,483::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:41.781200 seconds. 2024-04-14 17:35:56,516::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 17:38:37,358::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:41.874905 seconds. 2024-04-14 17:38:38,392::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 17:41:19,939::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:42.581095 seconds. 2024-04-14 17:41:20,932::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 17:44:02,184::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:42.244869 seconds. 2024-04-14 17:44:02,194::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF711XSR.mcool' in 0:15:48.543657. 2024-04-14 17:44:02,248::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF736ITL.mcool'... 2024-04-14 17:44:02,317::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 17:45:30,777::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:28.528930. 2024-04-14 17:47:00,239::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 17:47:00,239::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF736ITL.mcool' in 0:02:57.991410. 2024-04-14 17:47:00,239::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 17:47:01,258::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 17:49:40,586::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:40.346752 seconds. 2024-04-14 17:49:41,589::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 17:52:21,056::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:40.469371 seconds. 2024-04-14 17:52:22,063::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 17:55:01,474::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:40.418025 seconds. 2024-04-14 17:55:02,521::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 17:57:40,372::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:38.898112 seconds. 2024-04-14 17:57:41,404::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 18:00:19,185::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:38.812275 seconds. 2024-04-14 18:00:19,196::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF736ITL.mcool' in 0:16:16.948078. 2024-04-14 18:00:19,250::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF782WVZ.mcool'... 2024-04-14 18:00:19,307::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 18:01:42,994::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:23.744648. 2024-04-14 18:02:55,838::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 18:02:55,838::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF782WVZ.mcool' in 0:02:36.588536. 2024-04-14 18:02:55,838::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 18:02:56,848::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 18:05:32,800::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:36.961712 seconds. 2024-04-14 18:05:33,851::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 18:08:09,935::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:37.134845 seconds. 2024-04-14 18:08:10,965::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 18:10:46,796::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:36.860096 seconds. 2024-04-14 18:10:47,833::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 18:13:26,250::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:39.454413 seconds. 2024-04-14 18:13:27,283::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 18:16:05,778::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:39.527375 seconds. 2024-04-14 18:16:05,789::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF782WVZ.mcool' in 0:15:46.539213. 2024-04-14 18:16:05,843::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF783KQI.mcool'... 2024-04-14 18:16:05,889::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 18:17:24,984::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:19.141354. 2024-04-14 18:19:17,474::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 18:19:17,474::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF783KQI.mcool' in 0:03:11.631724. 2024-04-14 18:19:17,475::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 18:19:18,486::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 18:21:54,693::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:37.217903 seconds. 2024-04-14 18:21:55,734::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 18:24:31,846::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:37.153426 seconds. 2024-04-14 18:24:32,886::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 18:27:08,934::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:37.087368 seconds. 2024-04-14 18:27:09,975::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 18:29:47,320::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:38.385908 seconds. 2024-04-14 18:29:48,351::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 18:32:26,120::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:38.799550 seconds. 2024-04-14 18:32:26,130::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF783KQI.mcool' in 0:16:20.286854. 2024-04-14 18:32:26,184::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF791UZC.mcool'... 2024-04-14 18:32:26,250::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 18:33:45,296::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:19.111936. 2024-04-14 18:34:45,233::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 18:34:45,233::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF791UZC.mcool' in 0:02:19.049091. 2024-04-14 18:34:45,233::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 18:34:46,222::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 18:37:21,946::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:36.713103 seconds. 2024-04-14 18:37:22,975::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 18:39:58,409::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:36.463019 seconds. 2024-04-14 18:39:59,450::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 18:42:35,134::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:36.724568 seconds. 2024-04-14 18:42:36,141::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 18:45:13,535::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:38.400369 seconds. 2024-04-14 18:45:14,577::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 18:47:52,075::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:38.540216 seconds. 2024-04-14 18:47:52,086::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF791UZC.mcool' in 0:15:25.902562. 2024-04-14 18:47:52,140::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF839VMS.mcool'... 2024-04-14 18:47:52,200::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 18:49:15,414::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:23.273699. 2024-04-14 18:50:50,718::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 18:50:50,718::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF839VMS.mcool' in 0:02:58.578555. 2024-04-14 18:50:50,719::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 18:50:51,713::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 18:53:27,358::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:36.639239 seconds. 2024-04-14 18:53:28,430::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 18:56:06,000::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:38.641994 seconds. 2024-04-14 18:56:07,036::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 18:58:44,758::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:38.758079 seconds. 2024-04-14 18:58:45,785::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 19:01:26,218::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:41.459735 seconds. 2024-04-14 19:01:27,260::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 19:04:08,293::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:42.074584 seconds. 2024-04-14 19:04:08,304::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF839VMS.mcool' in 0:16:16.164143. 2024-04-14 19:04:08,351::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF842DUO.mcool'... 2024-04-14 19:04:08,419::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 19:05:31,061::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:22.709185. 2024-04-14 19:06:23,396::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 19:06:23,396::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF842DUO.mcool' in 0:02:15.044938. 2024-04-14 19:06:23,396::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 19:06:24,408::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 19:09:02,116::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:38.719262 seconds. 2024-04-14 19:09:03,112::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 19:11:41,795::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:39.678991 seconds. 2024-04-14 19:11:42,795::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 19:14:21,817::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:40.021444 seconds. 2024-04-14 19:14:22,815::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 19:17:02,527::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:40.710731 seconds. 2024-04-14 19:17:03,544::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 19:19:42,556::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:40.028802 seconds. 2024-04-14 19:19:42,566::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF842DUO.mcool' in 0:15:34.214990. 2024-04-14 19:19:42,613::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF883XXW.mcool'... 2024-04-14 19:19:42,669::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 19:21:05,465::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:22.851472. 2024-04-14 19:22:43,354::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 19:22:43,354::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF883XXW.mcool' in 0:03:00.740938. 2024-04-14 19:22:43,355::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 19:22:44,341::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 19:25:20,580::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:37.224921 seconds. 2024-04-14 19:25:21,579::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 19:27:57,552::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:36.972151 seconds. 2024-04-14 19:27:58,556::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 19:30:34,394::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:36.841378 seconds. 2024-04-14 19:30:35,427::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 19:33:14,463::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:40.069439 seconds. 2024-04-14 19:33:15,475::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 19:35:54,798::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:40.334508 seconds. 2024-04-14 19:35:54,809::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF883XXW.mcool' in 0:16:12.195546. 2024-04-14 19:35:54,863::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF897KRI.mcool'... 2024-04-14 19:35:54,923::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 19:37:12,949::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:18.085911. 2024-04-14 19:37:53,936::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 19:37:53,937::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF897KRI.mcool' in 0:01:59.073778. 2024-04-14 19:37:53,937::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 19:37:54,924::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 19:40:31,190::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:37.253051 seconds. 2024-04-14 19:40:32,178::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 19:43:08,280::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:37.090094 seconds. 2024-04-14 19:43:09,272::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 19:45:45,792::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:37.511914 seconds. 2024-04-14 19:45:46,823::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 19:48:25,585::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:39.792437 seconds. 2024-04-14 19:48:26,625::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 19:51:06,112::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:40.527399 seconds. 2024-04-14 19:51:06,124::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF897KRI.mcool' in 0:15:11.260914. 2024-04-14 19:51:06,172::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF911AHQ.mcool'... 2024-04-14 19:51:06,227::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 19:52:30,111::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:23.939608. 2024-04-14 19:53:48,509::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 19:53:48,510::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF911AHQ.mcool' in 0:02:42.337955. 2024-04-14 19:53:48,510::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 19:53:49,517::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 19:56:26,242::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:37.731737 seconds. 2024-04-14 19:56:27,258::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 19:59:03,754::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:37.512619 seconds. 2024-04-14 19:59:04,780::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 20:01:41,448::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:37.693537 seconds. 2024-04-14 20:01:42,472::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 20:04:21,775::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:40.327026 seconds. 2024-04-14 20:04:22,808::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 20:07:00,818::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:39.042219 seconds. 2024-04-14 20:07:00,829::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF911AHQ.mcool' in 0:15:54.657137. 2024-04-14 20:07:00,876::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF925QIF.mcool'... 2024-04-14 20:07:00,946::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 20:08:27,146::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:26.270452. 2024-04-14 20:09:22,827::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 20:09:22,827::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF925QIF.mcool' in 0:02:21.951228. 2024-04-14 20:09:22,827::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 20:09:23,843::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 20:11:58,844::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:36.016554 seconds. 2024-04-14 20:11:59,852::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 20:14:34,816::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:35.972222 seconds. 2024-04-14 20:14:35,841::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 20:17:11,199::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:36.382278 seconds. 2024-04-14 20:17:12,226::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 20:19:50,270::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:39.070673 seconds. 2024-04-14 20:19:51,294::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 20:22:29,532::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:39.261843 seconds. 2024-04-14 20:22:29,541::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF925QIF.mcool' in 0:15:28.665593. 2024-04-14 20:22:29,593::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF943JRY.mcool'... 2024-04-14 20:22:29,644::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 20:23:50,503::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:20.909848. 2024-04-14 20:24:30,493::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 20:24:30,494::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF943JRY.mcool' in 0:02:00.900479. 2024-04-14 20:24:30,494::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 20:24:31,515::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 20:27:06,871::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:36.376872 seconds. 2024-04-14 20:27:07,890::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 20:29:43,379::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:36.508157 seconds. 2024-04-14 20:29:44,406::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 20:32:19,900::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:36.520346 seconds. 2024-04-14 20:32:20,945::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 20:34:58,928::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:39.028419 seconds. 2024-04-14 20:34:59,961::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 20:37:37,797::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:38.868232 seconds. 2024-04-14 20:37:37,807::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF943JRY.mcool' in 0:15:08.213379. 2024-04-14 20:37:37,854::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF952JZV.mcool'... 2024-04-14 20:37:37,928::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 20:39:12,289::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:34.434787. 2024-04-14 20:41:05,927::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 20:41:05,927::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF952JZV.mcool' in 0:03:28.072746. 2024-04-14 20:41:05,927::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 20:41:06,941::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 20:43:42,127::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:36.199797 seconds. 2024-04-14 20:43:43,165::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 20:46:18,729::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:36.602062 seconds. 2024-04-14 20:46:19,766::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 20:48:55,043::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:36.313748 seconds. 2024-04-14 20:48:56,078::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 20:51:34,362::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:39.318327 seconds. 2024-04-14 20:51:35,401::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 20:54:13,627::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:39.264921 seconds. 2024-04-14 20:54:13,638::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF952JZV.mcool' in 0:16:35.783592. 2024-04-14 20:54:13,685::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF958DWQ.mcool'... 2024-04-14 20:54:13,738::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 20:55:34,561::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:20.876058. 2024-04-14 20:56:32,716::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 20:56:32,716::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF958DWQ.mcool' in 0:02:19.030614. 2024-04-14 20:56:32,716::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 20:56:33,734::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 20:59:09,068::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:36.352068 seconds. 2024-04-14 20:59:10,113::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 21:01:45,376::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:36.307946 seconds. 2024-04-14 21:01:46,410::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 21:04:21,656::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:36.280004 seconds. 2024-04-14 21:04:22,691::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 21:07:02,044::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:40.387965 seconds. 2024-04-14 21:07:03,073::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 21:09:42,049::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:40.004275 seconds. 2024-04-14 21:09:42,059::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF958DWQ.mcool' in 0:15:28.373672. 2024-04-14 21:09:42,106::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF962EDB.mcool'... 2024-04-14 21:09:42,163::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 21:11:04,193::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:22.087020. 2024-04-14 21:12:49,418::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 21:12:49,418::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF962EDB.mcool' in 0:03:07.312158. 2024-04-14 21:12:49,418::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 21:12:50,423::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 21:15:26,541::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:37.122129 seconds. 2024-04-14 21:15:27,582::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 21:18:03,517::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:36.975869 seconds. 2024-04-14 21:18:04,555::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 21:20:40,308::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:36.790846 seconds. 2024-04-14 21:20:41,354::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 21:23:19,529::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:39.221281 seconds. 2024-04-14 21:23:20,574::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 21:25:59,484::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:39.954653 seconds. 2024-04-14 21:25:59,495::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF962EDB.mcool' in 0:16:17.389043. 2024-04-14 21:25:59,543::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF965BPU.mcool'... 2024-04-14 21:25:59,604::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 21:27:23,459::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:23.915801. 2024-04-14 21:28:12,302::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 21:28:12,302::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF965BPU.mcool' in 0:02:12.759393. 2024-04-14 21:28:12,302::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 21:28:13,324::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 21:30:49,469::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:37.166221 seconds. 2024-04-14 21:30:50,499::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 21:33:26,548::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:37.079137 seconds. 2024-04-14 21:33:27,575::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 21:36:03,757::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:37.208365 seconds. 2024-04-14 21:36:04,767::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 21:38:43,527::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:39.770017 seconds. 2024-04-14 21:38:44,554::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 21:41:23,486::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:39.959035 seconds. 2024-04-14 21:41:23,496::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF965BPU.mcool' in 0:15:23.952979. 2024-04-14 21:41:23,543::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ENCFF980NXK.mcool'... 2024-04-14 21:41:23,623::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 21:42:47,247::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:23.703682. 2024-04-14 21:44:32,452::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 21:44:32,452::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ENCFF980NXK.mcool' in 0:03:08.908876. 2024-04-14 21:44:32,453::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 21:44:33,468::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 21:47:09,491::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:37.038202 seconds. 2024-04-14 21:47:10,522::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 21:49:46,487::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:36.996409 seconds. 2024-04-14 21:49:47,514::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 21:52:23,691::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:37.203602 seconds. 2024-04-14 21:52:24,727::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 21:55:03,448::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:39.756738 seconds. 2024-04-14 21:55:04,478::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 21:57:43,598::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:40.150105 seconds. 2024-04-14 21:57:43,610::INFO::decompose_cooler_file: Finished decomposition for 'ENCFF980NXK.mcool' in 0:16:20.065993. 2024-04-14 21:57:43,658::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'ESC-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool'... 2024-04-14 21:57:43,724::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 21:58:59,869::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:16.211484. 2024-04-14 22:00:14,417::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 22:00:14,417::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'ESC-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool' in 0:02:30.758986. 2024-04-14 22:00:14,417::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 22:00:15,428::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 22:02:51,045::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:36.627692 seconds. 2024-04-14 22:02:52,083::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 22:05:27,498::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:36.453015 seconds. 2024-04-14 22:05:28,539::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 22:08:04,104::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:36.605632 seconds. 2024-04-14 22:08:05,140::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 22:10:43,507::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:39.402860 seconds. 2024-04-14 22:10:44,547::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 22:13:22,698::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:39.190704 seconds. 2024-04-14 22:13:22,709::INFO::decompose_cooler_file: Finished decomposition for 'ESC-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool' in 0:15:39.050790. 2024-04-14 22:13:22,762::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'HB-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool'... 2024-04-14 22:13:22,804::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 22:14:38,553::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:15.791682. 2024-04-14 22:16:14,895::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 22:16:14,895::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'HB-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool' in 0:02:52.133401. 2024-04-14 22:16:14,895::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 22:16:15,915::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 22:18:51,809::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:36.913613 seconds. 2024-04-14 22:18:52,862::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 22:21:28,598::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:36.789323 seconds. 2024-04-14 22:21:29,651::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 22:24:05,259::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:36.660175 seconds. 2024-04-14 22:24:06,303::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 22:26:44,585::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:39.325939 seconds. 2024-04-14 22:26:45,626::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 22:29:24,181::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:39.595423 seconds. 2024-04-14 22:29:24,192::INFO::decompose_cooler_file: Finished decomposition for 'HB-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool' in 0:16:01.429912. 2024-04-14 22:29:24,239::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'hESC_pool.hg38.mapq_30.100.mcool'... 2024-04-14 22:29:24,275::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 22:30:36,993::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:12.754136. 2024-04-14 22:31:10,768::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 22:31:10,768::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'hESC_pool.hg38.mapq_30.100.mcool' in 0:01:46.529167. 2024-04-14 22:31:10,769::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 22:31:11,785::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 22:33:47,436::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:36.667772 seconds. 2024-04-14 22:33:48,483::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 22:36:24,160::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:36.723580 seconds. 2024-04-14 22:36:25,202::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 22:39:00,473::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:36.312752 seconds. 2024-04-14 22:39:01,522::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 22:41:40,103::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:39.629295 seconds. 2024-04-14 22:41:41,142::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 22:44:19,406::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:39.303358 seconds. 2024-04-14 22:44:19,417::INFO::decompose_cooler_file: Finished decomposition for 'hESC_pool.hg38.mapq_30.100.mcool' in 0:14:55.177878. 2024-04-14 22:44:19,464::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'iHEP-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool'... 2024-04-14 22:44:19,499::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 22:45:36,209::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:16.744879. 2024-04-14 22:46:54,265::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 22:46:54,265::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'iHEP-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool' in 0:02:34.801514. 2024-04-14 22:46:54,266::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 22:46:55,273::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 22:49:32,483::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:38.217742 seconds. 2024-04-14 22:49:33,525::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 22:52:09,315::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:36.831675 seconds. 2024-04-14 22:52:10,352::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 22:54:46,589::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:37.273660 seconds. 2024-04-14 22:54:47,638::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 22:57:31,461::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:44.872002 seconds. 2024-04-14 22:57:32,510::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 23:00:16,440::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:44.978919 seconds. 2024-04-14 23:00:16,451::INFO::decompose_cooler_file: Finished decomposition for 'iHEP-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool' in 0:15:56.987576. 2024-04-14 23:00:16,505::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'mHEP-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool'... 2024-04-14 23:00:16,574::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 23:01:36,439::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:19.934404. 2024-04-14 23:02:14,495::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 23:02:14,495::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'mHEP-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool' in 0:01:57.990649. 2024-04-14 23:02:14,496::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 23:02:15,513::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 23:04:56,633::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:42.137660 seconds. 2024-04-14 23:04:57,670::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 23:07:38,725::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:42.091121 seconds. 2024-04-14 23:07:39,775::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 23:10:20,576::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:41.850746 seconds. 2024-04-14 23:10:21,620::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 23:13:05,309::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:44.733275 seconds. 2024-04-14 23:13:06,356::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 23:15:50,154::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:44.844641 seconds. 2024-04-14 23:15:50,165::INFO::decompose_cooler_file: Finished decomposition for 'mHEP-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool' in 0:15:33.660326. 2024-04-14 23:15:50,219::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'PGT_pool.hg38.mapq_30.100.mcool'... 2024-04-14 23:15:50,245::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 23:17:11,228::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:21.009260. 2024-04-14 23:17:54,508::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 23:17:54,508::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'PGT_pool.hg38.mapq_30.100.mcool' in 0:02:04.289363. 2024-04-14 23:17:54,508::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 23:17:55,517::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 23:20:36,736::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:42.227873 seconds. 2024-04-14 23:20:37,785::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 23:23:18,898::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:42.161264 seconds. 2024-04-14 23:23:19,947::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 23:26:01,124::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:42.225906 seconds. 2024-04-14 23:26:02,169::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 23:28:46,238::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:45.114017 seconds. 2024-04-14 23:28:47,286::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 23:31:31,470::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:45.231661 seconds. 2024-04-14 23:31:31,480::INFO::decompose_cooler_file: Finished decomposition for 'PGT_pool.hg38.mapq_30.100.mcool' in 0:15:41.261079. 2024-04-14 23:31:31,534::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'PH_pool.hg38.mapq_30.100.mcool'... 2024-04-14 23:31:31,561::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 23:32:54,232::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:22.697306. 2024-04-14 23:34:45,147::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 23:34:45,147::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'PH_pool.hg38.mapq_30.100.mcool' in 0:03:13.612695. 2024-04-14 23:34:45,147::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 23:34:46,126::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 23:37:27,660::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:42.512917 seconds. 2024-04-14 23:37:28,716::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 23:40:10,285::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:42.624814 seconds. 2024-04-14 23:40:11,293::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 23:42:51,943::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:41.658143 seconds. 2024-04-14 23:42:52,950::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-14 23:45:36,678::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:44.734749 seconds. 2024-04-14 23:45:37,689::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-14 23:48:21,766::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:45.087504 seconds. 2024-04-14 23:48:21,776::INFO::decompose_cooler_file: Finished decomposition for 'PH_pool.hg38.mapq_30.100.mcool' in 0:16:50.241579. 2024-04-14 23:48:21,829::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'PP_pool.hg38.mapq_30.100.mcool'... 2024-04-14 23:48:21,863::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-14 23:49:32,735::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:10.905452. 2024-04-14 23:50:12,739::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-14 23:50:12,740::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'PP_pool.hg38.mapq_30.100.mcool' in 0:01:50.910436. 2024-04-14 23:50:12,740::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-14 23:50:13,752::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-14 23:52:53,354::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:40.613852 seconds. 2024-04-14 23:52:54,397::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-14 23:55:33,154::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:39.800243 seconds. 2024-04-14 23:55:34,192::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-14 23:58:13,115::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:39.960865 seconds. 2024-04-14 23:58:14,159::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-15 00:00:55,976::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:42.861051 seconds. 2024-04-15 00:00:57,018::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-15 00:03:40,022::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:44.045441 seconds. 2024-04-15 00:03:40,033::INFO::decompose_cooler_file: Finished decomposition for 'PP_pool.hg38.mapq_30.100.mcool' in 0:15:18.204049. 2024-04-15 00:03:40,086::INFO::decompose_cooler_file: Computing dimensionality reduction for input file: 'SC_Beta_pool.hg38.mapq_30.100.mcool'... 2024-04-15 00:03:40,131::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 00:05:01,303::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:21.216493. 2024-04-15 00:06:24,929::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 00:06:24,929::DEBUG::decompose_cooler_file: Finished preprocessing matrix for 'SC_Beta_pool.hg38.mapq_30.100.mcool' in 0:02:44.842927. 2024-04-15 00:06:24,930::DEBUG::minibatch_fit: Split matrix into 5 batches. 2024-04-15 00:06:25,915::DEBUG::minibatch_fit: Fitting batch: 1 with nrows: 8700. 2024-04-15 00:09:06,410::DEBUG::minibatch_fit: Finished fitting batch: 1 in 0:02:41.480242 seconds. 2024-04-15 00:09:07,460::DEBUG::minibatch_fit: Fitting batch: 2 with nrows: 8700. 2024-04-15 00:11:48,276::DEBUG::minibatch_fit: Finished fitting batch: 2 in 0:02:41.866192 seconds. 2024-04-15 00:11:49,318::DEBUG::minibatch_fit: Fitting batch: 3 with nrows: 8700. 2024-04-15 00:14:29,938::DEBUG::minibatch_fit: Finished fitting batch: 3 in 0:02:41.661911 seconds. 2024-04-15 00:14:30,984::DEBUG::minibatch_fit: Fitting batch: 4 with nrows: 8699. 2024-04-15 00:17:13,903::DEBUG::minibatch_fit: Finished fitting batch: 4 in 0:02:43.963990 seconds. 2024-04-15 00:17:14,937::DEBUG::minibatch_fit: Fitting batch: 5 with nrows: 8699. 2024-04-15 00:19:58,052::DEBUG::minibatch_fit: Finished fitting batch: 5 in 0:02:44.149299 seconds. 2024-04-15 00:19:58,063::INFO::decompose_cooler_file: Finished decomposition for 'SC_Beta_pool.hg38.mapq_30.100.mcool' in 0:16:17.976638. 2024-04-15 00:19:58,111::INFO::run: Model training complete. Training time: 1 day, 12:12:49.974158. 2024-04-15 00:19:58,111::INFO::run: Computing embeddings using fully trained model... 2024-04-15 00:19:58,111::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'day00_ESC_pool.hg38.mapq_30.100.mcool'... 2024-04-15 00:19:58,137::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 00:21:17,562::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:19.451329. 2024-04-15 00:22:27,523::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 00:22:30,854::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'day02_mesoderm_pool.hg38.mapq_30.100.mcool'... 2024-04-15 00:22:30,865::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 00:23:53,961::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:23.106286. 2024-04-15 00:25:08,552::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 00:25:11,786::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'day05_cardiacMesoderm_pool.hg38.mapq_30.100.mcool'... 2024-04-15 00:25:11,796::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 00:26:36,050::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:24.263689. 2024-04-15 00:27:47,738::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 00:27:50,990::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'day07_cardiacProgenitor_pool.hg38.mapq_30.100.mcool'... 2024-04-15 00:27:51,018::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 00:29:12,266::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:21.275088. 2024-04-15 00:30:50,883::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 00:30:54,103::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'day15_primativeCardiomyocyte_pool.hg38.mapq_30.100.mcool'... 2024-04-15 00:30:54,112::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 00:32:14,383::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:20.279370. 2024-04-15 00:32:58,534::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 00:33:01,775::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'day80_ventricularCardiomyocyte_pool.hg38.mapq_30.100.mcool'... 2024-04-15 00:33:01,784::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 00:34:29,990::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:28.215072. 2024-04-15 00:36:05,872::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 00:36:09,107::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'DE-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool'... 2024-04-15 00:36:09,116::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 00:37:30,842::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:21.734342. 2024-04-15 00:38:03,797::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 00:38:07,045::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'DE_pool.hg38.mapq_30.100.mcool'... 2024-04-15 00:38:07,053::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 00:39:31,868::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:24.823665. 2024-04-15 00:40:37,055::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 00:40:40,315::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF004YZQ.mcool'... 2024-04-15 00:40:40,326::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 00:42:09,899::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:29.583471. 2024-04-15 00:43:46,340::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 00:43:49,740::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF009ONH.mcool'... 2024-04-15 00:43:49,752::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 00:45:11,047::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:21.306329. 2024-04-15 00:45:45,541::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 00:45:48,932::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF019YVI.mcool'... 2024-04-15 00:45:48,943::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 00:47:16,216::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:27.283950. 2024-04-15 00:48:49,008::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 00:48:52,386::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF029UAL.mcool'... 2024-04-15 00:48:52,398::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 00:50:18,872::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:26.485477. 2024-04-15 00:51:24,520::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 00:51:27,874::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF035BLF.mcool'... 2024-04-15 00:51:27,884::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 00:52:54,345::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:26.470891. 2024-04-15 00:54:39,717::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 00:54:43,051::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF044TCQ.mcool'... 2024-04-15 00:54:43,062::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 00:56:04,055::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:21.004010. 2024-04-15 00:57:15,641::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 00:57:19,025::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF059WMS.mcool'... 2024-04-15 00:57:19,034::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 00:58:37,048::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:18.022572. 2024-04-15 00:59:55,390::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 00:59:58,728::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF076LWH.mcool'... 2024-04-15 00:59:58,739::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 01:01:21,891::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:23.162431. 2024-04-15 01:02:06,645::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 01:02:09,995::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF081PMO.mcool'... 2024-04-15 01:02:10,006::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 01:03:34,966::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:24.970417. 2024-04-15 01:04:52,634::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 01:04:55,929::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF094KKX.mcool'... 2024-04-15 01:04:55,939::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 01:06:19,041::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:23.111572. 2024-04-15 01:06:52,798::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 01:06:56,151::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF136XCV.mcool'... 2024-04-15 01:06:56,164::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 01:08:20,000::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:23.848919. 2024-04-15 01:09:09,226::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 01:09:12,609::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF140ROU.mcool'... 2024-04-15 01:09:12,619::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 01:10:33,779::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:21.169654. 2024-04-15 01:12:18,373::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 01:12:21,798::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF149IHN.mcool'... 2024-04-15 01:12:21,808::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 01:13:39,185::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:17.386279. 2024-04-15 01:14:08,927::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 01:14:12,283::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF176LIZ.mcool'... 2024-04-15 01:14:12,294::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 01:15:38,170::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:25.886833. 2024-04-15 01:17:13,707::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 01:17:17,038::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF185AYZ.mcool'... 2024-04-15 01:17:17,049::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 01:18:37,670::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:20.631791. 2024-04-15 01:19:42,954::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 01:19:46,362::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF193CQL.mcool'... 2024-04-15 01:19:46,373::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 01:21:13,719::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:27.356163. 2024-04-15 01:22:52,600::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 01:22:55,967::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF197OWW.mcool'... 2024-04-15 01:22:55,978::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 01:24:19,796::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:23.828352. 2024-04-15 01:25:22,673::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 01:25:26,038::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF224HKR.mcool'... 2024-04-15 01:25:26,048::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 01:26:47,342::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:21.303425. 2024-04-15 01:28:27,335::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 01:28:30,746::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF235LCO.mcool'... 2024-04-15 01:28:30,757::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 01:29:53,402::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:22.655638. 2024-04-15 01:30:26,401::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 01:30:29,709::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF251VFA.mcool'... 2024-04-15 01:30:29,721::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 01:31:55,213::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:25.504221. 2024-04-15 01:33:10,430::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 01:33:13,739::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF252ANV.mcool'... 2024-04-15 01:33:13,749::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 01:34:32,981::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:19.242202. 2024-04-15 01:35:06,928::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 01:35:10,252::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF273XBU.mcool'... 2024-04-15 01:35:10,263::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 01:36:40,023::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:29.770565. 2024-04-15 01:37:56,490::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 01:37:59,852::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF284OEA.mcool'... 2024-04-15 01:37:59,864::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 01:39:24,682::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:24.830322. 2024-04-15 01:41:13,613::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 01:41:16,950::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF309UNV.mcool'... 2024-04-15 01:41:16,961::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 01:42:43,769::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:26.818921. 2024-04-15 01:43:04,778::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 01:43:08,086::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF333WCK.mcool'... 2024-04-15 01:43:08,100::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 01:44:41,379::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:33.292075. 2024-04-15 01:46:12,403::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 01:46:15,728::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF355NFJ.mcool'... 2024-04-15 01:46:15,742::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 01:47:40,548::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:24.819594. 2024-04-15 01:48:36,897::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 01:48:40,221::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF355VJW.mcool'... 2024-04-15 01:48:40,234::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 01:50:08,020::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:27.799635. 2024-04-15 01:51:47,381::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 01:51:50,759::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF395INO.mcool'... 2024-04-15 01:51:50,772::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 01:53:21,746::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:30.986968. 2024-04-15 01:54:18,445::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 01:54:21,983::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF417GBZ.mcool'... 2024-04-15 01:54:21,996::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 01:55:47,750::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:25.766364. 2024-04-15 01:57:24,088::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 01:57:27,410::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF442IGJ.mcool'... 2024-04-15 01:57:27,424::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 01:58:48,916::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:21.505540. 2024-04-15 01:59:25,708::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 01:59:29,037::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF458VBB.mcool'... 2024-04-15 01:59:29,058::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 02:00:53,516::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:24.478170. 2024-04-15 02:02:11,791::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 02:02:15,116::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF493SFI.mcool'... 2024-04-15 02:02:15,129::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 02:03:33,783::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:18.666335. 2024-04-15 02:04:09,897::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 02:04:13,274::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF493YNC.mcool'... 2024-04-15 02:04:13,287::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 02:05:42,973::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:29.698738. 2024-04-15 02:06:51,490::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 02:06:54,861::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF496GEU.mcool'... 2024-04-15 02:06:54,873::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 02:08:17,309::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:22.448113. 2024-04-15 02:10:05,204::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 02:10:08,643::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF499BVX.mcool'... 2024-04-15 02:10:08,671::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 02:11:32,574::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:23.930521. 2024-04-15 02:11:53,230::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 02:11:56,551::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF515ZBF.mcool'... 2024-04-15 02:11:56,562::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 02:13:21,865::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:25.313552. 2024-04-15 02:14:55,814::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 02:14:59,191::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF520GFL.mcool'... 2024-04-15 02:14:59,202::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 02:16:27,079::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:27.888023. 2024-04-15 02:17:18,798::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 02:17:22,177::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF545GBW.mcool'... 2024-04-15 02:17:22,190::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 02:18:46,106::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:23.928917. 2024-04-15 02:20:32,915::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 02:20:36,309::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF556RLR.mcool'... 2024-04-15 02:20:36,323::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 02:21:55,634::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:19.324404. 2024-04-15 02:22:46,585::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 02:22:49,900::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF558DYU.mcool'... 2024-04-15 02:22:49,913::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 02:24:11,744::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:21.843529. 2024-04-15 02:25:35,366::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 02:25:38,745::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF571GTF.mcool'... 2024-04-15 02:25:38,758::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 02:26:58,572::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:19.826333. 2024-04-15 02:27:35,928::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 02:27:39,258::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF579CAR.mcool'... 2024-04-15 02:27:39,271::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 02:29:08,299::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:29.040932. 2024-04-15 02:30:24,187::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 02:30:27,599::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF586MQY.mcool'... 2024-04-15 02:30:27,611::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 02:31:57,314::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:29.715166. 2024-04-15 02:32:32,103::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 02:32:35,430::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF591MHA.mcool'... 2024-04-15 02:32:35,444::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 02:34:05,766::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:30.335038. 2024-04-15 02:35:30,422::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 02:35:33,735::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF605CEN.mcool'... 2024-04-15 02:35:33,747::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 02:36:57,289::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:23.553744. 2024-04-15 02:38:27,851::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 02:38:31,262::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF614IPZ.mcool'... 2024-04-15 02:38:31,275::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 02:39:57,493::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:26.229952. 2024-04-15 02:40:20,526::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 02:40:23,856::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF625VNK.mcool'... 2024-04-15 02:40:23,866::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 02:41:55,661::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:31.804729. 2024-04-15 02:43:37,477::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 02:43:40,893::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF628LQQ.mcool'... 2024-04-15 02:43:40,903::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 02:45:03,009::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:22.116279. 2024-04-15 02:45:52,685::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 02:45:56,025::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF653HCO.mcool'... 2024-04-15 02:45:56,038::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 02:47:21,352::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:25.326836. 2024-04-15 02:49:20,773::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 02:49:24,154::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF654YIQ.mcool'... 2024-04-15 02:49:24,166::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 02:50:42,981::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:18.826756. 2024-04-15 02:51:23,220::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 02:51:26,532::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF660JWA.mcool'... 2024-04-15 02:51:26,545::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 02:52:54,829::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:28.296321. 2024-04-15 02:54:40,042::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 02:54:43,331::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF663FRL.mcool'... 2024-04-15 02:54:43,344::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 02:56:07,398::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:24.066521. 2024-04-15 02:56:40,429::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 02:56:43,796::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF684YCT.mcool'... 2024-04-15 02:56:43,810::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 02:58:13,919::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:30.122480. 2024-04-15 02:59:36,662::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 02:59:40,000::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF687ATD.mcool'... 2024-04-15 02:59:40,014::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 03:01:09,118::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:29.118076. 2024-04-15 03:01:47,966::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 03:01:51,318::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF700CYI.mcool'... 2024-04-15 03:01:51,332::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 03:03:23,436::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:32.117657. 2024-04-15 03:04:44,777::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 03:04:48,114::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF705YZH.mcool'... 2024-04-15 03:04:48,126::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 03:06:12,340::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:24.226154. 2024-04-15 03:07:35,327::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 03:07:38,679::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF711XSR.mcool'... 2024-04-15 03:07:38,693::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 03:09:01,708::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:23.027846. 2024-04-15 03:09:28,771::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 03:09:32,185::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF736ITL.mcool'... 2024-04-15 03:09:32,199::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 03:11:13,465::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:41.280147. 2024-04-15 03:13:08,695::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 03:13:12,160::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF782WVZ.mcool'... 2024-04-15 03:13:12,173::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 03:14:33,352::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:21.191343. 2024-04-15 03:15:19,858::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 03:15:23,265::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF783KQI.mcool'... 2024-04-15 03:15:23,279::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 03:16:44,944::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:21.678490. 2024-04-15 03:18:35,961::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 03:18:39,396::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF791UZC.mcool'... 2024-04-15 03:18:39,411::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 03:20:01,067::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:21.670642. 2024-04-15 03:20:45,951::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 03:20:49,291::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF839VMS.mcool'... 2024-04-15 03:20:49,305::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 03:22:13,359::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:24.067490. 2024-04-15 03:23:46,878::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 03:23:50,284::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF842DUO.mcool'... 2024-04-15 03:23:50,298::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 03:25:13,095::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:22.810000. 2024-04-15 03:25:43,573::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 03:25:46,977::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF883XXW.mcool'... 2024-04-15 03:25:46,990::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 03:27:11,767::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:24.790462. 2024-04-15 03:28:54,940::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 03:28:58,326::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF897KRI.mcool'... 2024-04-15 03:28:58,340::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 03:30:19,263::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:20.936785. 2024-04-15 03:30:49,727::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 03:30:53,107::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF911AHQ.mcool'... 2024-04-15 03:30:53,121::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 03:32:16,000::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:22.892082. 2024-04-15 03:33:38,074::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 03:33:41,422::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF925QIF.mcool'... 2024-04-15 03:33:41,437::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 03:35:07,826::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:26.403136. 2024-04-15 03:36:39,989::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 03:36:43,290::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF943JRY.mcool'... 2024-04-15 03:36:43,303::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 03:38:01,486::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:18.195219. 2024-04-15 03:38:28,310::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 03:38:31,696::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF952JZV.mcool'... 2024-04-15 03:38:31,709::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 03:40:04,531::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:32.834543. 2024-04-15 03:41:52,975::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 03:41:56,397::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF958DWQ.mcool'... 2024-04-15 03:41:56,410::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 03:43:18,065::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:21.668718. 2024-04-15 03:44:04,969::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 03:44:08,449::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF962EDB.mcool'... 2024-04-15 03:44:08,462::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 03:45:29,524::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:21.075172. 2024-04-15 03:47:08,274::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 03:47:11,699::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF965BPU.mcool'... 2024-04-15 03:47:11,712::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 03:48:36,551::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:24.851350. 2024-04-15 03:49:25,931::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 03:49:29,282::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ENCFF980NXK.mcool'... 2024-04-15 03:49:29,321::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 03:50:52,183::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:22.900650. 2024-04-15 03:52:24,097::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 03:52:27,434::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'ESC-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool'... 2024-04-15 03:52:27,444::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 03:53:46,508::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:19.074200. 2024-04-15 03:54:15,380::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 03:54:18,663::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'HB-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool'... 2024-04-15 03:54:18,674::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 03:55:36,270::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:17.606950. 2024-04-15 03:57:11,370::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 03:57:14,615::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'hESC_pool.hg38.mapq_30.100.mcool'... 2024-04-15 03:57:14,624::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 03:58:25,324::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:10.709405. 2024-04-15 03:58:54,849::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 03:58:58,102::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'iHEP-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool'... 2024-04-15 03:58:58,112::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 04:00:14,058::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:15.955671. 2024-04-15 04:01:26,616::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 04:01:29,913::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'mHEP-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool'... 2024-04-15 04:01:29,943::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 04:02:49,948::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:20.035397. 2024-04-15 04:04:15,636::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 04:04:18,894::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'PGT_pool.hg38.mapq_30.100.mcool'... 2024-04-15 04:04:18,905::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 04:05:37,175::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:18.280536. 2024-04-15 04:06:02,689::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 04:06:06,011::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'PH_pool.hg38.mapq_30.100.mcool'... 2024-04-15 04:06:06,020::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 04:07:29,128::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:23.117286. 2024-04-15 04:09:20,178::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 04:09:23,927::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'PP_pool.hg38.mapq_30.100.mcool'... 2024-04-15 04:09:23,936::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 04:10:25,796::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:01.869192. 2024-04-15 04:11:07,757::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 04:11:11,027::INFO::compute_output_embeddings_single_file: Computing embeddings for input file: 'SC_Beta_pool.hg38.mapq_30.100.mcool'... 2024-04-15 04:11:11,036::INFO::preprocess_matrix: Loading preprocessed matrix from disk... 2024-04-15 04:12:28,521::DEBUG::preprocess_matrix: Loaded preprocessed matrix with shape '(57509, 57509)' from disk in 0:01:17.494519. 2024-04-15 04:14:08,948::DEBUG::preprocess_matrix: Removed bad bins from matrix. New shape: (43498, 43498) 2024-04-15 04:14:13,603::INFO::run: Saving results... 2024-04-15 04:14:14,034::INFO::save_model: Saved model to 'output_2024_04_13_12_07_PCA-32_50000bp_hg38_model.pkl.gz' in 0:00:00.431050. 2024-04-15 04:24:14,331::DEBUG::run: Output embeddings for filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:24:14,331::INFO::run: Saved embeddings to 'output_2024_04_13_12_07_PCA-32_50000bp_hg38_embeddings.csv.gz' and 'output_2024_04_13_12_07_PCA-32_50000bp_hg38_embeddings.pq'. 2024-04-15 04:24:14,331::INFO::run: Finished joint PCA in 1 day, 16:17:06.194836. 2024-04-15 04:24:14,562::INFO::__init__: PostProcessor :: configuration: ==================== Post Processor Configuration ==================== parquet_file : output_2024_04_13_12_07_PCA-32_50000bp_hg38_embeddings.pq output : output_2024_04_13_12_07_PCA-32_50000bp_hg38 umap_neighbours : [30, 100, 500] kmeans_clusters : [5, 6, 7, 8, 9, 10, 15, 20] leiden_resolutions : [0.1, 0.2, 0.3, 0.5, 0.8, 1.0] method : PCA log_level : DEBUG ======================================================================== 2024-04-15 04:24:15,300::INFO::run: Running post-processing 2024-04-15 04:24:16,866::INFO::normalize_embeddings: Normalizing embeddings for DE-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool 2024-04-15 04:24:19,164::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:24:19,165::INFO::normalize_embeddings: Normalizing embeddings for DE_pool.hg38.mapq_30.100.mcool 2024-04-15 04:24:21,420::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:24:21,421::INFO::normalize_embeddings: Normalizing embeddings for ENCFF004YZQ.mcool 2024-04-15 04:24:23,766::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:24:23,767::INFO::normalize_embeddings: Normalizing embeddings for ENCFF009ONH.mcool 2024-04-15 04:24:26,118::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:24:26,119::INFO::normalize_embeddings: Normalizing embeddings for ENCFF019YVI.mcool 2024-04-15 04:24:28,481::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:24:28,482::INFO::normalize_embeddings: Normalizing embeddings for ENCFF029UAL.mcool 2024-04-15 04:24:30,834::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:24:30,835::INFO::normalize_embeddings: Normalizing embeddings for ENCFF035BLF.mcool 2024-04-15 04:24:33,183::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:24:33,184::INFO::normalize_embeddings: Normalizing embeddings for ENCFF044TCQ.mcool 2024-04-15 04:24:35,533::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:24:35,534::INFO::normalize_embeddings: Normalizing embeddings for ENCFF059WMS.mcool 2024-04-15 04:24:37,890::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:24:37,891::INFO::normalize_embeddings: Normalizing embeddings for ENCFF076LWH.mcool 2024-04-15 04:24:40,244::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:24:40,245::INFO::normalize_embeddings: Normalizing embeddings for ENCFF081PMO.mcool 2024-04-15 04:24:42,602::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:24:42,603::INFO::normalize_embeddings: Normalizing embeddings for ENCFF094KKX.mcool 2024-04-15 04:24:44,950::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:24:44,951::INFO::normalize_embeddings: Normalizing embeddings for ENCFF136XCV.mcool 2024-04-15 04:24:47,299::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:24:47,300::INFO::normalize_embeddings: Normalizing embeddings for ENCFF140ROU.mcool 2024-04-15 04:24:49,657::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:24:49,658::INFO::normalize_embeddings: Normalizing embeddings for ENCFF149IHN.mcool 2024-04-15 04:24:52,010::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:24:52,011::INFO::normalize_embeddings: Normalizing embeddings for ENCFF176LIZ.mcool 2024-04-15 04:24:54,368::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:24:54,369::INFO::normalize_embeddings: Normalizing embeddings for ENCFF185AYZ.mcool 2024-04-15 04:24:56,717::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:24:56,718::INFO::normalize_embeddings: Normalizing embeddings for ENCFF193CQL.mcool 2024-04-15 04:24:59,071::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:24:59,072::INFO::normalize_embeddings: Normalizing embeddings for ENCFF197OWW.mcool 2024-04-15 04:25:01,421::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:25:01,422::INFO::normalize_embeddings: Normalizing embeddings for ENCFF224HKR.mcool 2024-04-15 04:25:03,771::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:25:03,773::INFO::normalize_embeddings: Normalizing embeddings for ENCFF235LCO.mcool 2024-04-15 04:25:06,131::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:25:06,132::INFO::normalize_embeddings: Normalizing embeddings for ENCFF251VFA.mcool 2024-04-15 04:25:08,481::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:25:08,482::INFO::normalize_embeddings: Normalizing embeddings for ENCFF252ANV.mcool 2024-04-15 04:25:10,836::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:25:10,837::INFO::normalize_embeddings: Normalizing embeddings for ENCFF273XBU.mcool 2024-04-15 04:25:13,192::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:25:13,193::INFO::normalize_embeddings: Normalizing embeddings for ENCFF284OEA.mcool 2024-04-15 04:25:15,545::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:25:15,547::INFO::normalize_embeddings: Normalizing embeddings for ENCFF309UNV.mcool 2024-04-15 04:25:17,900::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:25:17,901::INFO::normalize_embeddings: Normalizing embeddings for ENCFF333WCK.mcool 2024-04-15 04:25:20,251::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:25:20,252::INFO::normalize_embeddings: Normalizing embeddings for ENCFF355NFJ.mcool 2024-04-15 04:25:22,602::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:25:22,603::INFO::normalize_embeddings: Normalizing embeddings for ENCFF355VJW.mcool 2024-04-15 04:25:24,953::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:25:24,954::INFO::normalize_embeddings: Normalizing embeddings for ENCFF395INO.mcool 2024-04-15 04:25:27,305::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:25:27,306::INFO::normalize_embeddings: Normalizing embeddings for ENCFF417GBZ.mcool 2024-04-15 04:25:29,665::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:25:29,666::INFO::normalize_embeddings: Normalizing embeddings for ENCFF442IGJ.mcool 2024-04-15 04:25:32,017::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:25:32,018::INFO::normalize_embeddings: Normalizing embeddings for ENCFF458VBB.mcool 2024-04-15 04:25:34,360::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:25:34,361::INFO::normalize_embeddings: Normalizing embeddings for ENCFF493SFI.mcool 2024-04-15 04:25:36,718::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:25:36,719::INFO::normalize_embeddings: Normalizing embeddings for ENCFF493YNC.mcool 2024-04-15 04:25:39,070::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:25:39,071::INFO::normalize_embeddings: Normalizing embeddings for ENCFF496GEU.mcool 2024-04-15 04:25:41,419::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:25:41,420::INFO::normalize_embeddings: Normalizing embeddings for ENCFF499BVX.mcool 2024-04-15 04:25:43,767::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:25:43,768::INFO::normalize_embeddings: Normalizing embeddings for ENCFF515ZBF.mcool 2024-04-15 04:25:46,129::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:25:46,130::INFO::normalize_embeddings: Normalizing embeddings for ENCFF520GFL.mcool 2024-04-15 04:25:48,480::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:25:48,481::INFO::normalize_embeddings: Normalizing embeddings for ENCFF545GBW.mcool 2024-04-15 04:25:50,832::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:25:50,833::INFO::normalize_embeddings: Normalizing embeddings for ENCFF556RLR.mcool 2024-04-15 04:25:53,193::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:25:53,194::INFO::normalize_embeddings: Normalizing embeddings for ENCFF558DYU.mcool 2024-04-15 04:25:55,549::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:25:55,550::INFO::normalize_embeddings: Normalizing embeddings for ENCFF571GTF.mcool 2024-04-15 04:25:57,901::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:25:57,902::INFO::normalize_embeddings: Normalizing embeddings for ENCFF579CAR.mcool 2024-04-15 04:26:00,258::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:26:00,259::INFO::normalize_embeddings: Normalizing embeddings for ENCFF586MQY.mcool 2024-04-15 04:26:02,611::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:26:02,612::INFO::normalize_embeddings: Normalizing embeddings for ENCFF591MHA.mcool 2024-04-15 04:26:04,973::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:26:04,974::INFO::normalize_embeddings: Normalizing embeddings for ENCFF605CEN.mcool 2024-04-15 04:26:07,332::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:26:07,333::INFO::normalize_embeddings: Normalizing embeddings for ENCFF614IPZ.mcool 2024-04-15 04:26:09,682::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:26:09,683::INFO::normalize_embeddings: Normalizing embeddings for ENCFF625VNK.mcool 2024-04-15 04:26:12,034::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:26:12,035::INFO::normalize_embeddings: Normalizing embeddings for ENCFF628LQQ.mcool 2024-04-15 04:26:14,386::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:26:14,387::INFO::normalize_embeddings: Normalizing embeddings for ENCFF653HCO.mcool 2024-04-15 04:26:16,743::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:26:16,745::INFO::normalize_embeddings: Normalizing embeddings for ENCFF654YIQ.mcool 2024-04-15 04:26:19,102::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:26:19,103::INFO::normalize_embeddings: Normalizing embeddings for ENCFF660JWA.mcool 2024-04-15 04:26:21,454::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:26:21,455::INFO::normalize_embeddings: Normalizing embeddings for ENCFF663FRL.mcool 2024-04-15 04:26:23,801::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:26:23,802::INFO::normalize_embeddings: Normalizing embeddings for ENCFF684YCT.mcool 2024-04-15 04:26:26,153::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:26:26,154::INFO::normalize_embeddings: Normalizing embeddings for ENCFF687ATD.mcool 2024-04-15 04:26:28,503::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:26:28,504::INFO::normalize_embeddings: Normalizing embeddings for ENCFF700CYI.mcool 2024-04-15 04:26:30,856::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:26:30,857::INFO::normalize_embeddings: Normalizing embeddings for ENCFF705YZH.mcool 2024-04-15 04:26:33,207::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:26:33,208::INFO::normalize_embeddings: Normalizing embeddings for ENCFF711XSR.mcool 2024-04-15 04:26:35,564::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:26:35,565::INFO::normalize_embeddings: Normalizing embeddings for ENCFF736ITL.mcool 2024-04-15 04:26:37,922::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:26:37,923::INFO::normalize_embeddings: Normalizing embeddings for ENCFF782WVZ.mcool 2024-04-15 04:26:40,275::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:26:40,276::INFO::normalize_embeddings: Normalizing embeddings for ENCFF783KQI.mcool 2024-04-15 04:26:42,634::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:26:42,635::INFO::normalize_embeddings: Normalizing embeddings for ENCFF791UZC.mcool 2024-04-15 04:26:45,001::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:26:45,002::INFO::normalize_embeddings: Normalizing embeddings for ENCFF839VMS.mcool 2024-04-15 04:26:47,358::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:26:47,359::INFO::normalize_embeddings: Normalizing embeddings for ENCFF842DUO.mcool 2024-04-15 04:26:49,711::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:26:49,712::INFO::normalize_embeddings: Normalizing embeddings for ENCFF883XXW.mcool 2024-04-15 04:26:52,063::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:26:52,064::INFO::normalize_embeddings: Normalizing embeddings for ENCFF897KRI.mcool 2024-04-15 04:26:54,433::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:26:54,434::INFO::normalize_embeddings: Normalizing embeddings for ENCFF911AHQ.mcool 2024-04-15 04:26:56,791::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:26:56,792::INFO::normalize_embeddings: Normalizing embeddings for ENCFF925QIF.mcool 2024-04-15 04:26:59,140::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:26:59,141::INFO::normalize_embeddings: Normalizing embeddings for ENCFF943JRY.mcool 2024-04-15 04:27:01,501::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:27:01,502::INFO::normalize_embeddings: Normalizing embeddings for ENCFF952JZV.mcool 2024-04-15 04:27:03,853::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:27:03,854::INFO::normalize_embeddings: Normalizing embeddings for ENCFF958DWQ.mcool 2024-04-15 04:27:06,206::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:27:06,207::INFO::normalize_embeddings: Normalizing embeddings for ENCFF962EDB.mcool 2024-04-15 04:27:08,558::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:27:08,559::INFO::normalize_embeddings: Normalizing embeddings for ENCFF965BPU.mcool 2024-04-15 04:27:10,908::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:27:10,910::INFO::normalize_embeddings: Normalizing embeddings for ENCFF980NXK.mcool 2024-04-15 04:27:13,265::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:27:13,266::INFO::normalize_embeddings: Normalizing embeddings for ESC-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool 2024-04-15 04:27:15,522::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:27:15,523::INFO::normalize_embeddings: Normalizing embeddings for HB-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool 2024-04-15 04:27:17,782::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:27:17,783::INFO::normalize_embeddings: Normalizing embeddings for PGT_pool.hg38.mapq_30.100.mcool 2024-04-15 04:27:20,039::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:27:20,040::INFO::normalize_embeddings: Normalizing embeddings for PH_pool.hg38.mapq_30.100.mcool 2024-04-15 04:27:22,303::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:27:22,304::INFO::normalize_embeddings: Normalizing embeddings for PP_pool.hg38.mapq_30.100.mcool 2024-04-15 04:27:24,570::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:27:24,572::INFO::normalize_embeddings: Normalizing embeddings for SC_Beta_pool.hg38.mapq_30.100.mcool 2024-04-15 04:27:26,835::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:27:26,836::INFO::normalize_embeddings: Normalizing embeddings for day00_ESC_pool.hg38.mapq_30.100.mcool 2024-04-15 04:27:29,096::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:27:29,097::INFO::normalize_embeddings: Normalizing embeddings for day02_mesoderm_pool.hg38.mapq_30.100.mcool 2024-04-15 04:27:31,360::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:27:31,361::INFO::normalize_embeddings: Normalizing embeddings for day05_cardiacMesoderm_pool.hg38.mapq_30.100.mcool 2024-04-15 04:27:33,633::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:27:33,635::INFO::normalize_embeddings: Normalizing embeddings for day07_cardiacProgenitor_pool.hg38.mapq_30.100.mcool 2024-04-15 04:27:35,903::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:27:35,904::INFO::normalize_embeddings: Normalizing embeddings for day15_primativeCardiomyocyte_pool.hg38.mapq_30.100.mcool 2024-04-15 04:27:38,172::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:27:38,173::INFO::normalize_embeddings: Normalizing embeddings for day80_ventricularCardiomyocyte_pool.hg38.mapq_30.100.mcool 2024-04-15 04:27:40,432::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:27:40,433::INFO::normalize_embeddings: Normalizing embeddings for hESC_pool.hg38.mapq_30.100.mcool 2024-04-15 04:27:42,695::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:27:42,696::INFO::normalize_embeddings: Normalizing embeddings for iHEP-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool 2024-04-15 04:27:44,962::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:27:44,963::INFO::normalize_embeddings: Normalizing embeddings for mHEP-FA-DSG-DdeI-DpnII-P1P2.hg38.mapq_30.1000.mcool 2024-04-15 04:27:47,222::DEBUG::normalize_embeddings: Count of filenames: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-15 04:27:56,541::INFO::run: Components shape: (3914820, 32) 2024-04-15 04:27:56,541::INFO::run_kmeans: Running KMeans clustering with 5 clusters 2024-04-15 04:28:15,388::INFO::run_kmeans: Running KMeans clustering with 6 clusters 2024-04-15 04:28:43,072::INFO::run_kmeans: Running KMeans clustering with 7 clusters 2024-04-15 04:29:13,551::INFO::run_kmeans: Running KMeans clustering with 8 clusters 2024-04-15 04:29:45,306::INFO::run_kmeans: Running KMeans clustering with 9 clusters 2024-04-15 04:30:19,640::INFO::run_kmeans: Running KMeans clustering with 10 clusters 2024-04-15 04:30:51,051::INFO::run_kmeans: Running KMeans clustering with 15 clusters 2024-04-15 04:31:44,262::INFO::run_kmeans: Running KMeans clustering with 20 clusters 2024-04-15 04:32:43,079::INFO::run_leiden: Running Leiden clustering with 500 neighbors. 2024-04-15 15:57:54,323::INFO::run_leiden: Leiden clustering complete. 2024-04-15 15:58:22,286::INFO::run_leiden: Running Leiden clustering with 500 neighbors. 2024-04-16 02:25:34,084::INFO::run_leiden: Leiden clustering complete. 2024-04-16 02:25:55,185::INFO::run_leiden: Running Leiden clustering with 500 neighbors. 2024-04-16 13:05:43,047::INFO::run_leiden: Leiden clustering complete. 2024-04-16 13:06:03,912::INFO::run_leiden: Running Leiden clustering with 500 neighbors. 2024-04-17 03:50:09,310::INFO::run_leiden: Leiden clustering complete. 2024-04-17 03:50:30,640::INFO::run_leiden: Running Leiden clustering with 500 neighbors. 2024-04-17 22:45:15,828::INFO::run_leiden: Leiden clustering complete. 2024-04-17 22:45:37,382::INFO::run_leiden: Running Leiden clustering with 500 neighbors. 2024-04-18 13:05:04,808::INFO::run_leiden: Leiden clustering complete. 2024-04-18 13:05:26,061::INFO::run_umap: Running UMAP with 30 neighbors 2024-04-18 13:38:10,073::DEBUG::run_umap: Plotting UMAP for each filename in: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-18 13:38:41,786::INFO::run_umap: Running UMAP with 100 neighbors 2024-04-18 14:40:00,241::DEBUG::run_umap: Plotting UMAP for each filename in: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-18 14:40:26,923::INFO::run_umap: Running UMAP with 500 neighbors 2024-04-18 18:16:11,534::DEBUG::run_umap: Plotting UMAP for each filename in: day00_ESC_pool.hg38.mapq_30.100.mcool 57509 ENCFF783KQI.mcool 57509 ENCFF736ITL.mcool 57509 ENCFF711XSR.mcool 57509 ENCFF705YZH.mcool 57509 ... ENCFF252ANV.mcool 57509 ENCFF251VFA.mcool 57509 ENCFF235LCO.mcool 57509 ENCFF224HKR.mcool 57509 SC_Beta_pool.hg38.mapq_30.100.mcool 57509 Name: filename, Length: 90, dtype: int64 2024-04-18 18:16:38,175::INFO::plot_scores: Plotting scores 2024-04-18 18:17:11,643::INFO::run: Saving embeddings to parquet and csv 2024-04-18 18:28:25,234::INFO::run: Finished running post-processing 2024-04-18 18:28:25,238::INFO::__init__: TrajectoryAnalyzer :: configuration: ==================== Trajectory Analysis Configuration ==================== parquet_file : output_2024_04_13_12_07_PCA-32_50000bp_hg38_embeddings.pq output : output_2024_04_13_12_07_PCA-32_50000bp_hg38 kmeans_clusters : [5, 6, 7, 8, 9, 10, 15, 20] leiden_neighbors : 100 umap_neighbours : [30, 100, 500] method : PCA log_level : DEBUG ============================================================================= 2024-04-18 18:28:36,551::INFO::__init__: Shape of pivoted trajectory embeddings: (57509, 2884) 2024-04-18 18:28:36,551::INFO::run: Running trajectory analysis 2024-04-18 18:28:36,858::INFO::run_kmeans: Running KMeans clustering with 5 clusters 2024-04-18 18:28:49,012::INFO::run_kmeans: Running KMeans clustering with 6 clusters 2024-04-18 18:29:01,770::INFO::run_kmeans: Running KMeans clustering with 7 clusters 2024-04-18 18:29:20,581::INFO::run_kmeans: Running KMeans clustering with 8 clusters 2024-04-18 18:29:44,599::INFO::run_kmeans: Running KMeans clustering with 9 clusters 2024-04-18 18:30:07,325::INFO::run_kmeans: Running KMeans clustering with 10 clusters 2024-04-18 18:30:26,177::INFO::run_kmeans: Running KMeans clustering with 15 clusters 2024-04-18 18:30:49,898::INFO::run_kmeans: Running KMeans clustering with 20 clusters 2024-04-18 18:31:40,754::INFO::run_umap: Running UMAP with 30 neighbors 2024-04-18 18:32:02,696::INFO::run_umap: Running UMAP with 100 neighbors 2024-04-18 18:32:52,286::INFO::run_umap: Running UMAP with 500 neighbors 2024-04-18 18:43:28,060::INFO::run: Finished trajectory analysis 2024-04-18 18:43:29,151::INFO::main: Finished joint PCA